Innovative strategies for overcoming blood-brain barrier challenges in Alzheimer’s disease: A focus on green-synthesized metallic nanoparticles DOI

Kushagra Nagori,

Kartik T. Nakhate, Krishna Yadav

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: unknown, P. 113604 - 113604

Published: Nov. 1, 2024

Language: Английский

Emerging role of exosomes in cancer therapy: progress and challenges DOI Creative Commons
Jiale Li,

Jiachong Wang,

Zigui Chen

et al.

Molecular Cancer, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 13, 2025

This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple types. As small extracellular vesicles, exosomes exhibit high biocompatibility low immunogenicity, making them ideal vehicles capable of efficiently targeting cells, minimizing off-target damage side effects. aims to explore the potential with a focus on applications chemotherapy, gene immunomodulation. Additionally, challenges related production standardization are analyzed, highlighting importance addressing these issues clinical application. In conclusion, systems offer promising future therapies. Further research should aim enhance efficiency facilitate translation, paving way innovative treatment strategies.

Language: Английский

Citations

25
Facile synthesis of silver nanoparticles using Calotropis procera leaves: unraveling biological and electrochemical potentials DOI Creative Commons
Pooja V. Nagime,

Nishat M. Shaikh,

Sohel B. Shaikh

et al.

Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)

Published: Sept. 3, 2024

Highlights CPL-AgNPs exhibited improved biomimetic attributes. Antibiotic resistance against pathogens were challenged through use of CPL-AgNPs. Supercapacitor application facile synthesized AgNPs for the first time demonstrated physical application.

Language: Английский

Citations

18
Biogenic selenium nanoparticles: a comprehensive update on the multifaceted application, stability, biocompatibility, risk, and opportunity DOI
Pooja V. Nagime,

Vinay Kumar Pandey,

Charu Rajpal

et al.

Zeitschrift für Naturforschung C, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 8, 2025

Abstract Biogenic selenium nanoparticles (SeNPs) have emerged as promising area of research due to their unique properties and potential multifaceted applications. The biosynthesis SeNPs through biological methods, such using microorganism, plant extracts, etc., offers a safe, eco-friendly, biocompatible approach, compared traditional chemical synthesis. Recent several studies demonstrated that application includes broad antibacterial, anticancer, antioxidant, antiviral, anti-inflammatory, antidiabetic, excellent wound healing activity. On the other hand, also shown in sensing inorganic toxic metals, electrochemistry, agro-industries, aqua-cultures, fabrication solar panels. Additionally, capability enhance efficacy antibiotics act effective agents against multidrug-resistant pathogens has addressing critical health challenges. Although, exhibit wide applicability, toxicity Se, particularly its various oxidative states, necessitates careful assessment environmental impacts associated with use. Therefore, understanding balance between beneficial risks is crucial for safe This review focuses exclusively on synthesized via eco-friendly process, excluding utilizing synthesis processes. Moreover, this aims offer an overview diverse applications, risks, stability requirement, cytocompatibility opportunities SeNPs. Ultimately, bridges gap knowledge by providing updated details applications

Language: Английский

Citations

2
Phyto-mediated biosynthesis of silver nanoparticles using Aloe barbadensis Miller leaves gel with improved antibacterial, anti-fungal, antioxidant, anti-inflammatory, anti-diabetic, and anti-cancer activities DOI
Pooja V. Nagime,

Dwi Marlina Syukri,

Tessa Sjahriani

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 40, P. 101368 - 101368

Published: Oct. 3, 2024

Language: Английский

Citations

12
Biogenic metallic nanoparticles: from green synthesis to clinical translation DOI
Disha D. Shah, Mehul R. Chorawala, Mohammad Kaif A. Mansuri

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: 397(11), P. 8603 - 8631

Published: June 27, 2024

Language: Английский

Citations

9
Nanotechnology-based drug delivery for breast cancer treatment: Current applications and future directions DOI Creative Commons
Md Abdus Samad, Iftikhar Ahmad, Torki A. Zughaibi

et al.

European Journal of Medicinal Chemistry Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100268 - 100268

Published: April 1, 2025

Language: Английский

Citations

1
Unlocking the multifaceted potential of lipid-based dispersion as a drug carrier: Targeted applications and stability improvement strategies DOI
Abhijeet Puri, Popat Mohite, Shubham Munde

et al.

Journal of Dispersion Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 33

Published: April 28, 2025

Language: Английский

Citations

1
Surfactant-Free Synthesis of Metal and Metal Oxide Nanomaterials: Sustainable and Eco-Synthesis Methods DOI

Sayali Churi,

Ushasi Das, Popat Mohite

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Bacterial synthesis of anisotropic gold nanoparticles DOI Creative Commons
Islam M. Ahmady, Javad B. M. Parambath, Elsiddig A. E. Elsheikh

et al.

Applied Microbiology and Biotechnology, Journal Year: 2025, Volume and Issue: 109(1)

Published: March 10, 2025

Abstract Pseudomonas aeruginosa was used to synthesize anisotropic gold nanoparticles from the unusually reducible aryldiazonium (III) salt of chemical formula [HOOC-4-C 6 H 4 N≡N]AuCl (abbreviated as DS-AuCl ). We investigated effect bacterial cell density, temperature, and pH on AuNP synthesis. The density 6.0 × 10 8 CFU/mL successfully reduced 0.5 mM AuNPs after incubation at 37 °C (24 h), 42 25 (48 h). Transmission electron microscopy (TEM) images revealed formation spherical, triangle, star, hexagon, truncated triangular morphologies for synthesized using P. bacteria. average size h) 39.0 ± 9.1 nm, 26.0 8.1 36.7 7.7 respectively. 3.7, 7.0, 12.7 14.7 3.8 7.3 2.5 respectively, with decreasing a 12.7. reduction confirmed X-ray photoelectron spectroscopy (XPS). significant peaks C1s, Au4f doublet, N1s, O1s are centered 285, 84–88, 400, 532 eV. ability inactivated bacteria (autoclave-dead mechanically lysed bacteria), peptidoglycan, lipopolysaccharides reduce also investigated. Anisotropic were peptidoglycan but not lipopolysaccharides. demonstrated biocompatibility human RBCs safe, no antibacterial activities against Escherichia coli Staphylococcus aureus . This is first report demonstrating synthesis gold(III) salts These promising candidates exploring potential applications in nanomedicine drug delivery. Key points • Dead residues AuNPs. hemocompatible. Graphical

Language: Английский

Citations

0
Fabrication of a nanoplatform based on chitosan and hyaluronic acid containing alkyne-functionalized gold nanoparticles for tumor targeted synergistic phototherapy DOI
Tan Ding,

Haixin Long,

M. C. Du

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142974 - 142974

Published: April 1, 2025

Language: Английский

Citations

0