BMC Microbiology, Journal Year: 2025, Volume and Issue: 25(1)
Published: May 30, 2025
Language: Английский
Bioinorganic Chemistry and Applications, Journal Year: 2025, Volume and Issue: 2025(1)
Published: Jan. 1, 2025
To treat urinary tract infections (UTIs), biosynthesized silver and yttrium‐doped nanoparticles (AgNPs Y‐AgNPs) were synthesized from pine needle leaf extract (PNLE). The crystalline nature of the NPs was demonstrated by X‐ray diffraction. Transmission scanning electron microscopy showed that AgNPs Y‐AgNPs are dispersed spherical, with average particle sizes 18.43 26.58 nm, respectively. chemical composition oxidation states revealed photoelectron spectroscopy, while elemental compositions explored energy‐dispersive analysis. functional groups absorbance peaks Fourier transform infrared spectroscopy ultraviolet‐visible possessed luminescent behavior based on photoluminescence studies ferromagnetic according to vibrating sample magnetometer In addition, antibacterial activity against six uropathogenic bacteria assessed performing microdilution assays determine minimum inhibitory concentration (MIC) bactericidal (MBC) which ranged between 0.0625 2 mg/mL, agar well diffusion assay zones inhibition 8–17 mm, time‐kill test detecting after 3 h, antibiofilm screening at concentrations ranging 1 mg/mL. antioxidant determined 1,1, diphenyl 1‐2 picrylhydrazyl (DPPH) radical scavenging assay, a significant (14.2%–55.6%). Docking can inhibit vital enzymes DNA gyrase, penicillin‐binding proteins, carbapenemase, LasR‐binding protein, dihydropteroate synthase. These results highlight use as alternative approaches in battle antibiotic‐resistant UTIs. research illustrates increased bioactivity compared conventional AgNPs. It paves way for novel nanomaterials antimicrobial medicine.
Language: Английский
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The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100356 - 100356
Published: April 1, 2025
Language: Английский
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Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)
Published: May 6, 2025
Language: Английский
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Biomedicines, Journal Year: 2025, Volume and Issue: 13(5), P. 1184 - 1184
Published: May 13, 2025
Drug resistance is a serious problem for human health worldwide. Day by day this drug increasing and creating an anxious situation the treatment of both cancer infectious diseases caused pathogenic microorganisms. Researchers are trying to solve terrible overcome resistance. Biosynthesized gold nanoparticles (AuNPs) could be promising agent controlling drug-resistant microorganisms cells. AuNPs can synthesized via chemical physical approaches, carrying many threats ecosystem. Green synthesis using biological agents such as plants microbes most fascinating attractive alternative physicochemical it offers advantages, simplicity, non-toxicity, cost-effectiveness, eco-friendliness. Plant extracts contain numerous biomolecules, produce various metabolites that act reducing, capping, stabilizing during AuNPs. The characterization green-synthesized has been conducted multiple instruments including UV-Vis spectrophotometry (UV-Vis), transmission electron microscopy (TEM), scanning (SEM), atomic force (AFM), X-ray diffraction (XRD), DLS, Fourier transform infrared spectroscopy (FT-IR). have detrimental effects on bacterial cells disruption cell membranes, fragmentation DNA, production reactive oxygen species, impairment metabolism. biocompatibility biosafety must investigated proper in vitro vivo screening model system. In review, we emphasized green, facile, eco-friendly their potential antimicrobial anticancer applications highlighted antibacterial mechanisms. This study demonstrates may potentially used control bacteria well
Language: Английский
Citations
0
BMC Microbiology, Journal Year: 2025, Volume and Issue: 25(1)
Published: May 30, 2025
Language: Английский
Citations
0