Development of a digital intervention for psychedelic preparation (DIPP)

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 19, 2024

Abstract Psychedelic substances induce profound alterations in consciousness. Careful preparation is therefore essential to limit adverse reactions, enhance therapeutic benefits, and maintain user safety. This paper describes the development of a self-directed, digital intervention for psychedelic preparation. Drawing on elements from UK Medical Research Council (MRC) framework developing complex interventions, design was informed by four-factor model preparedness, using person-centred approach. Our mixed-methods investigation consisted two studies. The first involved interviews with 19 participants who had previously attended ‘high-dose’ psilocybin retreat, systematically exploring their behaviours perspectives proposed intervention. second study engaged 28 attendees an ongoing retreat co-design workshops, refining protocol insights initial interviews. outcome co-produced 21-day course (Digital Intervention Preparation (DIPP)), that organised into four modules: Knowledge–Expectation, Psychophysical–Readiness, Safety–Planning, Intention–Preparation. Fundamental components include daily meditation practice, supplementary exercises tied weekly modules, mood tracking. DIPP provides comprehensive scalable solution aligning broader shift towards mental health interventions.

Language: Английский

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Can psychedelic use benefit meditation practice? Examining individual, psychedelic, and meditation-related factors

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0310160 - e0310160

Published: Feb. 12, 2025

Meditation practice and psychedelic use have attracted increasing attention in the public sphere scientific research. Both methods induce non-ordinary states of consciousness that may significant therapeutic benefits. Thus, there is growing interest potential synergies between meditation with some research suggesting psychedelics benefit practice. The present study examined individual, psychedelic-related, meditation-related factors to determine under what conditions meditators perceive as beneficial for their Participants (N = 863) who had reported a regular (at least 3 times per week during last 12 months) were included study. To accommodate large number variables, machine learning (i.e., elastic net, random forest) was used analyze data. Most participants (n 634, 73.5%) found positive influence on quality meditation. Twenty-eight variables showed zero-order associations perceived benefits even following correction. Elastic net best performance (R2 .266) identify most important features. Across 53 model greater psychedelics, intention setting use, agreeableness, exposure N,N-Dimethyltryptamine (N,N-DMT) likely be associated perception results consistent across several different approaches Shapley values, feature ablation). Results suggest practice, with: 1) regularity 2) intentions 3) having an agreeable personality, 4) N,N-DMT being predictors perceiving beneficial. Longitudinal designs randomized trials manipulating are needed establish causality.

Language: Английский

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Acceptance and Self-Compassion: Mind-Body Approaches to Psychosomatic Disorders

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Psychosomatic disorders involve a complex interplay between psychological distress and physical symptoms, often exacerbated by maladaptive cognitive emotional responses. This chapter explores the role of Acceptance Commitment Therapy (ACT) self-compassion as effective mind-body interventions for managing these conditions. ACT fosters flexibility, enabling individuals to accept distressing thoughts bodily sensations without avoidance while engaging in values-based actions. Self-compassion, on other hand, helps reduce self-criticism, distress, coping mechanisms promoting self-kindness, mindfulness, sense shared humanity. Empirical research highlights efficacy reducing symptom anxiety, depression, functional impairment with chronic pain psychosomatic disorders. Clinical applications, including group therapy models, online interventions, assessment tools, demonstrate their adaptability across different therapeutic settings. By integrating acceptance, compassion-based strategies, not only alleviate suffering but also enhance overall well-being. synthesizes current research, clinical methodologies, intervention offering comprehensive framework incorporating into treatment approaches The findings emphasize importance shifting from elimination values-driven living, providing holistic sustainable approach mental health.

Language: Английский

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Music mindfulness acutely modulates autonomic activity and improves psychological state in anxiety and depression

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 8, 2025

Anxiety and depression reduce autonomic system activity, as measured by Heart Rate Variability (HRV), exacerbate cardiac morbidity. Both music mindfulness have been shown to increase HRV, clinical approaches incorporating these interventions show promise effective treatments for symptoms of anxiety depression. Music mindfulness, which combines listening with activities, may provide unique synergistic therapeutic benefits stress management. However, date, no studies evaluated the physiological mechanisms underlying a community-based paradigm. We used wearable technology record electrocardiography electroencephalography signals from participants moderate during also assessed impact our session on participant's psychological state. found that sessions acutely enhanced multiple measures HRV altered EEG power spectral density across various frequency bands in frontotemporal electrodes. live virtual reduced participants' state consciousness; however, only fostered social connection. Additionally, effects varied based self-reported sex. Overall, findings demonstrate effectively engages neural mechanisms, contribute treatment symptoms.

Language: Английский

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Can Psychedelic Use Benefit Meditation Practice? Examining Individual, Psychedelic, and Meditation-Related Factors

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 28, 2024

Abstract Introduction Meditation practice and psychedelic use have attracted increasing attention in the public sphere scientific research. Both methods induce non-ordinary states of consciousness that may significant therapeutic benefits. Thus, there is growing interest potential synergies between meditation with some research suggesting psychedelics benefit practice. The present study examined individual, psychedelic-related, meditation-related factors to determine under what conditions meditators perceive as beneficial for their Method Participants ( N = 863) who had reported a regular (at least 3 times per week during last 12 months) were included study. To accommodate large number variables, machine learning (i.e., elastic net, random forest) was used analyze data. Results Most participants n 634, 73.5%) found positive influence on quality meditation. Twenty-eight variables showed zero-order associations perceived benefits even following correction. Elastic net best performance (R 2 .266) identify most important features. Across 53 model greater psychedelics, intention setting use, agreeableness, exposure N,N-Dimethyltryptamine (N,N-DMT) likely be associated perception results consistent across several different approaches Shapley values, feature ablation). Discussion suggest practice, with: 1) regularity 2) intentions 3) having an agreeable personality, 4) N,N-DMT being predictors perceiving beneficial. Longitudinal designs randomized trials manipulating are needed establish causality.

Language: Английский

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Enhancing Subjective Well-Being in Taiwanese University Students Through an Eight-Week Mindfulness-Based Program: A Pilot Study

Behavioral Sciences, Journal Year: 2024, Volume and Issue: 14(11), P. 980 - 980

Published: Oct. 22, 2024

While mindfulness has demonstrated extensive benefits across diverse populations, research on its integration as a formal course and effects subjective well-being (SWB), particularly among Taiwanese university students, remains limited. This pilot study examined changes in SWB 85 students (61 males, 24 females) following an 8-week Mindfulness-Based Cognitive Therapy for Life (MBCT-L) course. Participants included 38 lower-grade (pre-internship) 47 senior (post-internship) students. was measured using the 29-item Oxford Happiness Questionnaire (OHQ), rated 6-point Likert scale, administered before after intervention. Results revealed significant increase students' overall scores from 3.69 to 3.92 post-intervention. Although females initially exhibited higher baseline compared no sex differences were observed Score discrepancies between pre- post-test stages varied internship status, indicating differential impacts of MBCT-L distinct demographic groups. Additionally, this validated reliability short version OHQ (8 items) use similar contexts. By conducting provides valuable empirical evidence, contributing cross-cultural understanding mindfulness-based interventions their SWB.

Language: Английский

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Psilocybin with Acceptance and Commitment Therapy (ACT) for the Treatment of Social Anxiety Disorder (SAD)

Published: March 1, 2024

Social Anxiety Disorder (SAD) is a debilitating mental health condition characterized by an overwhelming fear and anxiety of social rejection that can lead to chronic patterns behavioral avoidance. Despite the existence traditional efficacious treatments, significant number individuals either do not respond treatment or experience recurrence symptoms over extended periods, spanning 10-12 years. Acceptance Commitment Therapy (ACT), form acceptance-based therapy considered part "third wave" cognitive therapies, has shown promising results in early studies, comparable those Cognitive Behavioral (CBT) first-line for SAD. When combined with Psychedelic-Assisted Psychotherapy (PAP), ACT may offer viable alternative. This combination potential improve therapeutic outcomes addressing underlying emotional perpetuate SAD through biopsychosocial approach. paper examines theoretical basis, practical considerations, challenges associated this innovative

Language: Английский

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Development of a Digital Intervention for Psychedelic Preparation (DIPP): a theory- and person-centred approach

Published: Nov. 22, 2023

Psychedelic substances induce profound alterations in consciousness. Careful preparation is therefore essential to limit adverse reactions, enhance therapeutic benefits, and maintain user safety. This paper describes the development of a self-directed, digital intervention for psychedelic preparation. Drawing on elements from UK Medical Research Council (MRC) framework developing complex interventions, design was informed by four-factor model preparedness, using person-centred approach. Our mixed-methods investigation consisted two studies. The first involved interviews with 19 participants who had previously attended ‘high-dose’ psilocybin retreat, systematically exploring their behaviours perspectives proposed intervention. second study engaged 28 attendees an ongoing retreat co-design workshops, refining protocol insights initial interviews. outcome co-produced 21-day course (Digital Intervention Preparation (DIPP)), that organised into four modules: Knowledge-Expectation, Psychophysical-Readiness, Safety-Planning, Intention-Preparation. Fundamental components include daily meditation practice, supplementary exercises tied weekly modules, mood tracking. DIPP provides comprehensive scalable solution aligning broader shift towards mental health interventions.

Language: Английский

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