Seminars in Oncology, Journal Year: 2025, Volume and Issue: 52(3), P. 152349 - 152349
Published: May 8, 2025
Language: Английский
Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 296 - 296
Published: Feb. 24, 2025
Melanoma, a highly aggressive form of skin cancer, poses major therapeutic challenge due to its metastatic potential, resistance conventional therapies, and the complexity tumor microenvironment (TME). Materials science nanotechnology advances have led using nanocarriers such as liposomes, dendrimers, polymeric nanoparticles, metallic nanoparticles transformative solutions for precision melanoma therapy. This review summarizes findings from Web Science, PubMed, EMBASE, Scopus, Google Scholar highlights role in overcoming treatment barriers. Nanoparticles facilitate passive active targeting through mechanisms enhanced permeability retention (EPR) effect functionalization with tumor-specific ligands, thereby improving accuracy drug delivery reducing systemic toxicity. Stimuli-responsive systems multi-stage further improve overcome challenges poor penetration resistance. Emerging platforms combine diagnostic imaging delivery, paving way personalized medicine. However, there are still issues scalability, biocompatibility, regulatory compliance. comprehensive potential integrating genetics proteomics, scalable, patient-specific therapies. These interdisciplinary innovations promise redefine provide safer, more effective, accessible treatments. Continued research is essential bridge gap between evidence-based scientific clinical applications.
Language: Английский
Citations
1
International Journal of Scientific Research in Science and Technology, Journal Year: 2025, Volume and Issue: 12(1), P. 161 - 173
Published: Jan. 26, 2025
Iron oxide nanoparticles (IONPs) have emerged as a transformative tool in oncology, offering unprecedented opportunities for early cancer diagnosis and effective treatment. These exhibit unique physicochemical properties, including superparamagnetism, biocompatibility, large surface area-to-volume ratio. properties make them particularly suitable applications such high-resolution imaging, targeted drug delivery, hyperthermia therapy. Additionally, their ability to be functionalized with various biomolecules enables precision targeting of cancerous tissues, further enhancing efficacy. This article delves into the cutting-edge advancements utilization IONPs, examines multifunctional roles addresses challenges clinical translation, outlines future directions research application this dynamic field.
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142136 - 142136
Published: March 1, 2025
Language: Английский
Citations
0
Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 833 - 833
Published: March 21, 2025
Polymeric nanoparticles (PNPs) represent a groundbreaking advancement in targeted drug delivery, offering significant benefits over conventional systems. This includes their versatility, biocompatibility, and ability to encapsulate diverse therapeutic agents provide controlled release, improving efficacy while minimizing side effects. The polymers used PNP formulations are critical, as they influence the nanoparticles' physicochemical properties such size, shape, surface charge, drug-loading capacity. Recent developments polymer chemistry nanotechnology have led creation of smart PNPs that can respond specific stimuli, enabling precise release environments. review explores mechanisms innovations polymeric formulations, fabrication characterization techniques enhance delivery Additionally, it discusses challenges future directions field, highlighting potential for personalized medicine role artificial intelligence optimizing nanoparticle design. By examining relationship between characteristics performance, aims promote innovative strategies modern medicine. Despite promise polymer-based systems, toxicity, stability, scalability, regulatory compliance must be addressed. Future research should focus on rigorous testing, clear risk communication, sustainable practices support clinical translation commercial viability. Overall, integration these elements is crucial advancing applications.
Language: Английский
Citations
0
Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)
Published: May 8, 2025
Cancer remains one of the deadliest diseases globally, significantly impacting patients' quality life. Addressing rising incidence cancer deaths necessitates innovative approaches such as nanomedicine and artificial intelligence (AI). The convergence AI represents a transformative frontier in healthcare, promising unprecedented advancements diagnosis, treatment, patient management. This narrative review explores distinct applications oncology, alongside their synergistic potential. Nanomedicine leverages nanoparticles for targeted drug delivery, enhancing therapeutic efficacy while minimizing adverse effects. Concurrently, algorithms facilitate early detection, personalized treatment planning, predictive analytics, thereby optimizing clinical outcomes. Emerging integrations these technologies could transform care by facilitating precise, personalized, adaptive strategies. synthesizes current research, highlights individual applications, discusses emerging oncology. goal is to provide comprehensive understanding how cutting-edge can collaboratively improve prognosis.
Language: Английский
Citations
0
Seminars in Oncology, Journal Year: 2025, Volume and Issue: 52(3), P. 152349 - 152349
Published: May 8, 2025
Language: Английский
Citations
0