Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 69, P. 106636 - 106636
Published: Nov. 30, 2024
Language: Английский
Deleted Journal, Journal Year: 2024, Volume and Issue: 6(8)
Published: July 29, 2024
Abstract Arteriosclerosis (AS) presents a significant global health challenge, demanding innovative therapeutic strategies. This review explores the potential of nanoparticles (NPs) and mesenchymal stem cells (MSCs) as promising modalities for treating AS. NPs enable targeted drug delivery, while MSCs possess immunomodulatory regenerative capabilities. We discuss recent advances in NP-based delivery systems tailored AS treatment highlight MSCs’ roles modulating inflammation promoting vascular repair. Additionally, we examine synergistic effects combining enhanced outcomes. Furthermore, this paper provides insights into targeting endothelial cells, T-cells, macrophages, lipid levels, plaques using MSCs. It also reviews various types metal-based non-metallic utilized therapy. comprehensive overview underscores synergies between cardiovascular disease therapy, emphasizing need further research to fully realize their implications. Graphical
Language: Английский
Citations
13
Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 51(1)
Published: March 14, 2024
Language: Английский
Citations
11
Deleted Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
1
Journal of Essential Oil Research, Journal Year: 2024, Volume and Issue: 36(3), P. 271 - 290
Published: April 9, 2024
Ocimum species, including African basil (Ocimum gratissimum) and Holy sanctum), are valued for their diverse therapeutic properties particularly in the form of essential oils (EOs). This review provides a comprehensive analysis health potentials oils, specifically focusing on basil. It encompasses various aspects, such as isolation methods, phytochemical characterization, bioactivities, bioavailability, future directions. Various studies have highlighted bioactive compounds within these EOs, eugenol, camphor, α-pinene, attributing to wide-ranging benefits. Notably, EOs exhibit potent antimicrobial, antioxidant, anti-inflammatory, antidiabetic, anticancer properties, making them promising candidates alternative medicine pharmaceutical applications. However, rapid absorption poor bioavailability pose challenges, mitigated through nanoencapsulation techniques enhancing efficacy. Future research directions include mechanistic utilizing specialized cell cultures animal models, alongside clinical trials validate reported bioactivities. Optimization delivery systems exploration novel nano-formulations also optimizing complete potential oils. Lastly, efforts enhance EO yield augment bioactivity genetic strategies elicitation been suggested.
Language: Английский
Citations
5
Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)
Published: April 1, 2025
Abstract The agricultural sector plays a crucial role in global food security, yet its heavy reliance on chemical inputs has led to rise emerging contaminants modern agroecosystems. This review critically examines the impacts of these soil health, plant-soil interactions, and productivity. We highlight how xenobiotic compounds from pesticides, herbicides, antibiotics, fertilizers disrupt nutrient cycling microbial communities. Key contaminant classes, including pharmaceuticals, industrial pollutants, were discussed alongside their specific effects ecosystems. Additionally, this also explores innovative bio-based nano-enhanced remediation strategies, such as rhizosphere microbiome management nano-biofertilizers, which show promise mitigating impacts. Despite advancements, challenges persist regulatory frameworks, technology adoption, education. To address theses issues, we propose holistic approach integrating research, policy, stakeholder engagement. Our findings urgent need for sustainable practices that prioritize health ecosystem integrity ensure long-term security. Graphical
Language: Английский
Citations
0
Food and Chemical Toxicology, Journal Year: 2025, Volume and Issue: 202, P. 115483 - 115483
Published: April 29, 2025
Language: Английский
Citations
0
BMC Plant Biology, Journal Year: 2024, Volume and Issue: 24(1)
Published: Aug. 7, 2024
Abstract Background Tobacco mosaic virus (TMV) is a highly infectious plant that affects wide variety of plants and reduces crop yields around the world. Here, we assessed effectiveness using Ammi visnaga aqueous seed extract to synthesize silver nanoparticles (Ag-NPs) their potential combat TMV. Different techniques were used characterize Ag-NPs, such as scanning transmission electron microscopy (SEM, TEM), energy-dispersive X-ray spectroscopy (EDS), fourier transform infrared (FTIR), dynamic light scattering (DLS). Results TEM demonstrated synthesized Ag-NPs had spherical form with an average size 23–30 nm zeta value -15.9 mV, while FTIR revealed various functional groups involved in Ag-NP stability capping. Interestingly, Pre-treatment tobacco (protective treatment) at 100–500 µg/mL significantly suppressed viral symptoms, Post-treatment (curative delayed appearance. Furthermore, protective curative treatments increased chlorophyll b, total flavonoids, soluble carbohydrates, antioxidant enzymes activity (PPO, POX CAT). Simultaneously, application resulted decrease levels oxidative stress markers (H 2 O MDA). The RT-qPCR results volcano plot analysis showed trigger regulate transcription ten defense-related genes ( SbWRKY-1 , SbWRKY-2 JERF-3 GST-1 POD PR-1 PR-2 PR-12 PAL-1 HQT-1 ). heatmap primary gene anthocyanidin production, was consistently most expressed across all throughout study. Analysis co-expression network 9 central among studied genes, followed by . Conclusions Overall, reported antiviral properties and/or curative) biosynthesized against TMV lead us recommend simple, stable, eco-friendly agent developing pest management programs infections.
Language: Английский
Citations
1
ACS Omega, Journal Year: 2024, Volume and Issue: 9(43), P. 43302 - 43318
Published: Oct. 18, 2024
The vast diversity of plants in nature offers a rich reservoir bioactive compounds that have historically played an integral role pharmacotherapy and continue to serve as primary source novel therapeutic agents. Medicinal contain multitude secondary metabolites with pharmacological potential, making them indispensable drug discovery development. These constituents, inherent herbal remedies, exhibit wide range medicinal properties due their complex chemical compositions structural diversity. Despite the clinical application crude plant extracts is often hindered by limitations, such poor bioavailability, low biostability, variable efficacy. issues can diminish impact plant-derived compounds. Nanotechnology presents innovative approach addressing these challenges through development nanoformulations enhance efficacy This review examines both historical recent studies on synthesis characterization compounds, focusing effectiveness treating various diseases. Additionally, it addresses risks associated direct use medicine, explores extraction isolation techniques, reviews research from past five years nanoformulations, applications disease treatment. also trials conducted over last nanoformulated counterparts, providing insights into translation natural therapeutics.
Language: Английский
Citations
1
Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 69, P. 106636 - 106636
Published: Nov. 30, 2024
Language: Английский
Citations
1