Nanobiotechnology Unveils the Power of Probiotics: A Comprehensive Review on the Synergistic Role of Probiotics and Advanced Nanotechnology in Enhancing Geriatric Health.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

The geriatric population, comprising ages 65 and above, encounters distinct health obstacles because of physiological changes heightened vulnerability to diseases. New technologies are being investigated tackle the intricate requirements this population. Recent advancements in probiotics nanotechnology offer promising strategies enhance by improving nutrient absorption, modulating gut microbiota, delivering targeted therapeutic agents. Probiotics play a crucial role maintaining homeostasis, reducing inflammation, supporting metabolic functions. However, challenges such as limited viability efficacy harsh gastrointestinal conditions hinder their potential. Advanced can overcome these constraints enhancing through nano-encapsulation, controlled delivery, improvement bioavailability. This review explores synergistic potential advanced addressing age-related concerns. It highlights key developments probiotic formulations, nano-based delivery systems, combined impact on health, immunity, neuroprotection. convergence represents novel transformative approach promoting healthy aging, paving way for innovative interventions.

Language: Английский

Bio-inspired Synthesis of Silver and Zinc Oxide Nanoparticles Using Syzygium salicifolium: Unveiling Versatile In Vitro Biomedical and Photocatalytic Applications

Journal of Cluster Science, Journal Year: 2025, Volume and Issue: 36(3)

Published: April 25, 2025

Language: Английский

Appeal of Urolithins from Synthesis to Biological Activities

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Urolithins (Uros), a series of natural polyphenols derived from ellagic acid through gut bacteria metabolism, have gathered significant attention due to their diverse bioactivities such as maintaining mitochondrial health and anti-inflammatory antioxidative effects. However, the ability metabolize Uros varies among individuals. This Review provides comprehensive insight into synthesis, encapsulation Uros, focusing on biotransformation in vivo. We highlight critical role microbiota urolithins, including primary bacterial species Gordonibacter urolithinfaciens, Enterocloster bolteae Enterococcus faecium. Furthermore, therapeutic potential alleviating neurodegenerative diseases, cancer, Duchenne muscular dystrophy is discussed. Finally, several strategies for enhancing solubility bioavailability are summarized. Future research direction includes identifying key genes involved biotransformation, elucidating bioactive mechanisms improving bioavailability. In conclusion, we synthesized biosynthetic pathways properties better utilization management.

Language: Английский