Neurotherapeutics, Journal Year: 2023, Volume and Issue: 20(4), P. 911 - 913
Published: July 1, 2023
Language: Английский
Microorganisms, Journal Year: 2024, Volume and Issue: 12(4), P. 821 - 821
Published: April 18, 2024
Sex and gender are fundamental health determinants their role as modifiers of treatment response is increasingly recognized. Norepinephrine a cornerstone septic shock management its use based on the highest level evidence compared to dopamine. The related 2021 Surviving Sepsis Campaign (SCC) recommendation presumably applicable both females males; however, sex- gender-based analysis lacking, thus not allowing generalizable conclusions. This paper was aimed at exploring whether gender-disaggregated data available in supporting this recommendation. For all studies underpinning it, four pairs authors, including woman man, extracted concerning sex gender, according Gender Equity Research guidelines. Nine manuscripts were included with an overall population 2126 patients, which 43.2% females. No performed never reported. In conclusion, present manuscript highlighted that clinical underlying SCC NE administration have neglected likely response, missing opportunity gender-specific
Language: Английский
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0
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 73 - 81
Published: July 4, 2024
Language: Английский
Citations
0
Social Science & Medicine, Journal Year: 2024, Volume and Issue: 361, P. 117341 - 117341
Published: Sept. 14, 2024
Language: Английский
Citations
0
Journal of Alzheimer s Disease, Journal Year: 2024, Volume and Issue: 102(1), P. 110 - 118
Published: Oct. 17, 2024
Women comprise approximately two-thirds of Alzheimer's disease cases.
Language: Английский
Citations
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PLoS ONE, Journal Year: 2024, Volume and Issue: 19(11), P. e0313625 - e0313625
Published: Nov. 18, 2024
Background Researchers have increasingly recognized the importance of structural and social determinants health (SSDOH) as key drivers a multitude diseases outcomes. The Multi-Ethnic Study Atherosclerosis (MESA) is an ongoing, longitudinal cohort study subclinical cardiovascular disease (CVD) that has followed geographically racially/ethnically diverse participants starting in 2000. Since its inception, MESA incorporated numerous SSDOH assessments instruments to relation CVD aging In this paper, we describe data available MESA, systematically review published papers using were focused on provide roadmap for future SSDOH-related studies. Methods findings team reviewed all (n = 2,125) through January 23, 2023. Two individuals titles, abstracts, full text determine final number 431) at least one variable exposure, outcome, or stratifying/effect modifier main interest (discrepancies resolved by third individual). Fifty-seven percent racialized/ethnic groups other macrosocial/structural factors (e.g., segregation), 16% individual-level inequalities (e.g. income), 14% built environment walking destinations), 10% context neighborhood socioeconomic status), 34% stressors discrimination, air pollution), 4% support/integration participation). Forty-seven (11%) combined with cohorts cross-cohort comparisons replication/validation validating algorithms). Conclusions Overall, made significant contributions field literature, 20% SSDOH. Future studies would benefit recently added instruments/data early life educational quality), linking biomarkers underlying causal mechanisms outcomes, focusing intersectionality, understudied (i.e., support, context), outcomes sleep, respiratory health, cognition/dementia).
Language: Английский
Citations
0
Neurotherapeutics, Journal Year: 2023, Volume and Issue: 20(4), P. 911 - 913
Published: July 1, 2023
Language: Английский
Citations
0