Facile phyto-mediated synthesis of ternary CuO/Mn3O4/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations DOI Creative Commons
Shahira H. EL‐Moslamy, Yousra A. El‐Maradny, Mohamed H. El‐Sayed

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 8, 2025

The phyto-synthesis of ternary CuO/ Mn3O4/ZnO nanocomposite was achieved by the utilization an eco-friendly, straightforward approach that involved extract Nigella sativa seeds. Our appears to include equal amounts CuO, Mn3O4, and ZnO based on atomic percentages. results indicate a robust thermally stable CuO/Mn3O4/ZnO developed in nanosuspensions. nanocomposites showed antimicrobial capabilities against multidrug-resistant human pathogens. highest biofilm reduction viable planktonic populations all pathogens investigated significantly reduced with value 18.5 µg/mL. unique, enhanced, triple-combined properties enabled have strong ability. exhibited anticancer activity A549, MDA, HCT-116, HepG2 cells, selectivity index values ​​ranging from 24.72 41.96. appeared induce selective dose-dependent nuclear condensation cell shrinkage treated cancer inducing apoptosis mechanism combat progression. phytosynthetic triggering apoptotic mechanisms This pathway confirmed affinity for ErbBs VEGF potent antioxidant scavenge ABTS DPPH radicals at EC50 ​​of 236.6 µg/mL 134.8 µg/mL, respectively.

Language: Английский

Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators DOI Creative Commons
Samy Selim, Tarek M. Abdelghany, Mohammed S. Almuhayawi

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 15, 2025

Language: Английский

Citations

1
Green synthesis of trimetallic CuO/Ag/ZnO nanocomposite using Ziziphus spina-christi plant extract: characterization, statistically experimental designs, and antimicrobial assessment DOI Creative Commons
Ayman K. El‐Sawaf, Shahira H. EL‐Moslamy, Elbadawy A. Kamoun

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Aug. 24, 2024

Abstract In this study, Ziziphus spina christi leaves was used to synthesize a trimetallic CuO/Ag/ZnO nanocomposite by simple and green method. Many characterizations e.g. FTIR, UV–vis DRS, SEM–EDX, TEM, XRD, zeta-size analysis, DLS, were confirm green-synthesized nanocomposite. The green, synthesized exhibited spherical dot-like structure, with an average particle size of around 7.11 ± 0.67 nm zeta potential 21.5 mV. An extremely homogeneous distribution signals, including O (79.25%), Cu (13.78%), Zn (4.42%), Ag (2.55%), is evident on the surface green-synthetic nanocomposite, according EDX data. To best our knowledge, first study effectively use industrially produced as potent antimicrobial agent employing different statistically experimental designs. highest yield synthetic (1.65 mg/mL), which enhanced 1.85 5.7 times; respectively, using Taguchi approach in comparison Plackett–Burman strategy basal condition. A variety assays techniques utilized evaluate capabilities at 200 µg/mL concentration against multidrug-resistant human pathogens. After 36-h period, tested reduced planktonic viable counts studied bacteria, Escherichia coli Staphylococcus aureus , showed percentage biofilm reduction (98.06 0.93 97.47 0.65%; respectively).

Language: Английский

Citations

5
Facile synthesis of a new nanocomposite based on Ba(II)-substituted phosphomolybdate anchored on manganese oxide, PMo11Ba@MnO2, for oxygen evolution of water splitting reaction DOI
Mohammad Ali Rezvani,

Hadi Hassani Ardeshiri,

Alborz Babamir Satehi

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114032 - 114032

Published: Jan. 1, 2025

Language: Английский

Citations

0
Facile phyto-mediated synthesis of ternary CuO/Mn3O4/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations DOI Creative Commons
Shahira H. EL‐Moslamy, Yousra A. El‐Maradny, Mohamed H. El‐Sayed

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 8, 2025

The phyto-synthesis of ternary CuO/ Mn3O4/ZnO nanocomposite was achieved by the utilization an eco-friendly, straightforward approach that involved extract Nigella sativa seeds. Our appears to include equal amounts CuO, Mn3O4, and ZnO based on atomic percentages. results indicate a robust thermally stable CuO/Mn3O4/ZnO developed in nanosuspensions. nanocomposites showed antimicrobial capabilities against multidrug-resistant human pathogens. highest biofilm reduction viable planktonic populations all pathogens investigated significantly reduced with value 18.5 µg/mL. unique, enhanced, triple-combined properties enabled have strong ability. exhibited anticancer activity A549, MDA, HCT-116, HepG2 cells, selectivity index values ​​ranging from 24.72 41.96. appeared induce selective dose-dependent nuclear condensation cell shrinkage treated cancer inducing apoptosis mechanism combat progression. phytosynthetic triggering apoptotic mechanisms This pathway confirmed affinity for ErbBs VEGF potent antioxidant scavenge ABTS DPPH radicals at EC50 ​​of 236.6 µg/mL 134.8 µg/mL, respectively.

Language: Английский

Citations

0