IOP Conference Series Earth and Environmental Science,
Journal Year:
2025,
Volume and Issue:
1473(1), P. 012058 - 012058
Published: March 1, 2025
Abstract
Lactobacillus
acidophilus
(L.
acidophilus)
is
commonly
found
in
the
deep
caries.
Calcium
hydroxide,
a
standard
for
direct
pulp
capping,
has
drawbacks
such
as
tunnel
defects.
This
study
investigates
antibacterial
activity
of
chitosan
synthesized
from
Penaeus
monodon
(P.
monodon)
shell
at
various
concentrations
and
deacetylation
degrees
(DD)
against
L.
acidophilus.
Chitosan
P.
natural
resource
Tarakan,
Indonesia
with
DD
81.21%
92.96%
was
prepared,
each
diluted
on
3%;
1.5%;
0.75%;
0.375%;
0.188%;
0.094%;
0.046%;
0.023%.
Antibacterial
examined
by
dilution
method
colony
counting
BHI
agar.
Data
were
analyzed
using
Kruskal-Wallis
Mann-Whitney
tests.
showed
zero
growth
0.375%
to
3%,
while
0.023%
0.188%
performed
(11.25
115
CFU/ml).
Significant
differences
observed,
except
3%
(p<0.05).
0.094%
(10.5
86.5
In
conclusion,
effective
exhibited
pronounced
effectivity
3%.
Increasing
concentration
enhances
activity.
Polymer Engineering and Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 28, 2025
Abstract
This
study
explores
the
fabrication
and
characterization
of
chitosan/gelatin
(CS/G)
bioaerogels
loaded
with
Rambutan
Leaf
Extract
(RLE)
for
antibacterial
biocompatible
applications.
Chitosan
was
initially
extracted
from
shrimp
waste,
achieving
a
yield
16.28%
degree
deacetylation
76.42%.
RLE
via
Soxhlet
extraction
characterized
its
antioxidant
properties.
Bioaerogels
were
prepared
by
integrating
1%–5%
into
CS/G
matrix,
followed
freeze‐drying.
Thermal
analysis
showed
that
RLE‐enhanced
aerogels
exhibited
improved
thermal
stability,
maximum
decomposition
temperature
(T
max
)
shifting
318°C
in
control
to
324°C
5%
sample.
The
porosity
ranged
90%
95%,
while
density
increased
loading
90.7
97.2
mg/cm
3
.
Antibacterial
activity
against
E.
coli
S.
aureus
significantly
enhanced,
inhibition
zones
reaching
17.9
mm
20.8
mm,
respectively,
aerogels.
Cytotoxicity
proliferation
assays
confirmed
excellent
biocompatibility,
cell
viability
exceeding
enhanced
observed
RLE‐loaded
samples.
These
findings
demonstrate
offer
promising
platform
biomedical
cosmetic
applications,
combining
properties,
biocompatibility.
Highlights
successfully
waste
16.28%.
possesses
strong
loading,
maintaining
high
porosity.
Aerogels
mm.
tests
over
90%.
IOP Conference Series Earth and Environmental Science,
Journal Year:
2025,
Volume and Issue:
1473(1), P. 012058 - 012058
Published: March 1, 2025
Abstract
Lactobacillus
acidophilus
(L.
acidophilus)
is
commonly
found
in
the
deep
caries.
Calcium
hydroxide,
a
standard
for
direct
pulp
capping,
has
drawbacks
such
as
tunnel
defects.
This
study
investigates
antibacterial
activity
of
chitosan
synthesized
from
Penaeus
monodon
(P.
monodon)
shell
at
various
concentrations
and
deacetylation
degrees
(DD)
against
L.
acidophilus.
Chitosan
P.
natural
resource
Tarakan,
Indonesia
with
DD
81.21%
92.96%
was
prepared,
each
diluted
on
3%;
1.5%;
0.75%;
0.375%;
0.188%;
0.094%;
0.046%;
0.023%.
Antibacterial
examined
by
dilution
method
colony
counting
BHI
agar.
Data
were
analyzed
using
Kruskal-Wallis
Mann-Whitney
tests.
showed
zero
growth
0.375%
to
3%,
while
0.023%
0.188%
performed
(11.25
115
CFU/ml).
Significant
differences
observed,
except
3%
(p<0.05).
0.094%
(10.5
86.5
In
conclusion,
effective
exhibited
pronounced
effectivity
3%.
Increasing
concentration
enhances
activity.
