Journal of Natural Remedies,
Journal Year:
2024,
Volume and Issue:
unknown, P. 2713 - 2725
Published: Dec. 31, 2024
Background:
Cannabis
sativa
(CS)
has
been
traditionally
used
for
its
medicinal
properties,
including
antioxidant,
antibacterial,
and
neuroprotective
effects.
However,
potential
anticataleptic
activity
remains
unexplored.
Aim:
This
study
aimed
to
investigate
the
qualitative
phytochemical
analysis,
of
methanolic
seed
extract
(CSCME).
Methods:
The
antioxidant
CSCME
was
evaluated
using
DPPH
radical
scavenging
assay.
Antibacterial
properties
were
assessed
agar
well
diffusion
method.
For
study,
Wistar
albino
rats
(n=30)
divided
into
five
groups:
control,
disease
control
(haloperidol
1mg/kg),
standard
treatment
1mg/kg
+
trihexyphenidyl
two
groups
receiving
haloperidol
with
(10mg/kg
20mg/kg).
Treatments
administered
daily
15
days,
catalepsy
severity
block
metal
bar
methods.
Results:
exhibited
significant
antibacterial
comparable
commercial
drugs.
In
vivo,
results
showed
a
reduction
in
cataleptic
scores
(P<0.05)
compared
control.
Notably,
20mg/kg
group
demonstrated
similar
reductions
as
(P>0.05).
Conclusion:
demonstrates
that
possesses
activities,
suggesting
therapeutic
agent
managing
other
neurological
disorders.
findings
warrant
further
investigation
clinical
applications
CSCME.
Luminescence,
Journal Year:
2025,
Volume and Issue:
40(4)
Published: April 1, 2025
This
work
investigates
the
structural,
photocatalytic,
and
biological
properties
of
Juglans
regia
leaves
extract
mediated
chitosan-modified
TiO2
nanoparticles
(NPs)
NPs.
The
structural
morphological
analysis
conducted
using
X-ray
diffraction,
scanning
electron
microscopy,
transmission
FTIR
revealed
that
synthesizing
NPs
both
chitosan
results
in
lower
particle
size
less
agglomeration
comparison
to
synthesized
only
extract.
photocatalytic
activity
for
degradation
Rhodamine
B
phytomediated
has
a
remarkable
efficacy
95.07%
when
subjected
UV-visible
light.
Further,
have
ability
reduce
E2
estrogen
levels
which
inhibits
growth
breast
cancer
cells
(MCF-7)
was
confirmed
by
yeast
based
XenoScreen
XL
YES
assay,
[3H]
thymidine
incorporation,
apoptosis
gene
expression
(Casp
3
Casp
9)
analysis.
