Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141028 - 141028
Published: Feb. 1, 2025
Language: Английский
Citations
1Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112383 - 112383
Published: March 1, 2025
Language: Английский
Citations
0ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 7, 2025
Injectable hydrogels represent a highly promising approach for localized drug delivery systems (DDSs) in the management of bone-related conditions such as osteoporosis, osteonecrosis, osteoarthritis, osteomyelitis, and osteosarcoma. Their appeal lies their biocompatibility, adjustable mechanical properties, capacity to respond external stimuli, including pH, temperature, light, redox potential, ionic strength, enzymatic activity. These features enable enhanced targeted bioactive agents. This mini-review evaluates synthesis injectable well recent advancements treating range bone disorders, focusing on mechanisms sustained DDSs delivering drugs, nanoparticles, growth factors, cells (e.g., stem cells). Moreover, it highlights clinical studies disease treatment. Additionally, emphasizes potential synergy between hydrogel-based point-of-care technologies, which are anticipated play pivotal role future therapies. have transform treatment by facilitating precise, sustained, minimally invasive therapeutic delivery. Nevertheless, significant challenges, long-term scalability, reproducibility, precise regulation release kinetics, must be addressed unlock fully. Addressing these challenges will not only advance therapy but also open new avenues regenerative medicine personalized healthcare.
Language: Английский
Citations
0Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Citations
0