Journal of Advances in Medicine and Medical Research,
Journal Year:
2023,
Volume and Issue:
35(20), P. 43 - 49
Published: Aug. 19, 2023
Background:
Epigenetic
analyzes
associated
with
maternal
and
child
nutrition
are
the
subject
of
several
studies
due
to
their
crucial
role
in
fetal
development.
Significant
changes
diet
during
gestational
period
or
even
puerperium
can
lead
metabolic
diseases
neuropsychiatric
disorders.
Aims:
The
present
study
sought
carry
out
a
systematic
review
such
interactions
pre-
post-pregnancy
periods.
Study
Design:
Systematic
review.
Methodology:
Bibliographic
research
was
used
as
method
data
were
obtained
from
VHL
information
portal
2017
2021.
Original
articles
published
last
6
years,
related
nutritional
impacts
on
epigenetic
mechanisms,
whether
women
postpartum
newborns,
included
this
study.
In
newborns.
Results:
Nine
that
met
selection
criteria
topic
selected.
Conclusion:
Based
study,
it
possible
understand
relationship
between
expression
order
promote
area
facilitate
understanding
various
genomic
origin.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(21), P. 3781 - 3781
Published: Nov. 4, 2024
Background/Objectives:
Metabolic
Syndrome
(MetS)
is
an
increasingly
widespread
public
health
problem
worldwide.
MetS
associated
with
a
cafeteria
diet
characterized
by
high
fat
and
simple
carbohydrates.
A
significantly
affects
serum
glucose,
creatine,
urea,
triglyceride,
cholesterol
parameters
such
as
ALT,
AST
ALP.
Due
to
its
epigenetic
effects,
vitamin
D
important
in
controlling
minimizing
findings
subsequent
generations.
Methods:
In
this
study,
the
effect
of
weekly
0.3
mL
(1.000
IU/week)
intervention
on
was
investigated
parental
rats
developing
high-fructose
their
offspring.
Offspring
receiving
not
supplementation
were
divided
into
four
different
groups
exposed
for
eight
weeks.
Results:
It
shown
that
group
had
lower
total
cholesterol,
ALP,
ALT
levels
(p
<
0.05).
Serum
AST,
body
weights
HDL
higher
offspring
However,
initial
values
parent
than
supplemented
parents.
Conclusions:
conclusion,
it
found
improved
rats,
positively
affected
despite
inadequate
diet,
some
affecting
pathways
born
mothers.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(24), P. 4292 - 4292
Published: Dec. 12, 2024
Background/Objectives:
Inflammatory
bowel
disease
(IBD)
is
a
chronic
gastrointestinal
disorder
with
debilitating
symptoms
and
multifactorial
etiology.
Nutritional
factors
during
adult
life
have
been
implicated
in
IBD
pathogenesis.
In
addition,
there
growing
evidence
that
maternal
early-life
diet
may
be
associated
intestinal
inflammation
colitis
severity.
The
aim
of
the
current
review
was
to
detect
critically
appraise
all
regarding
role
on
inflammation.
Methods:
We
performed
thorough
search
literature
across
two
databases
(Pubmed,
ScienceDirect)
using
variety
relevant
terms.
Results:
A
total
23
studies,
16
experimental
7
clinical,
met
inclusion
criteria
were
included
this
review.
Experimental
studies
reveal
high-fat
high-protein
diets
gestation
neonatal
induce
gut
dysbiosis,
amplify
inflammation,
exacerbate
colitis.
nutritional
affect
offspring’s
microbiota
composition
health.
Human
concluded
quality
intake
fish
vegetables
food
fortified
vitamin
D
early
infancy
significantly
decreased
risk.
However,
human
data
are
limited,
larger
investigations
needed
further
clarify
complex
associations
between
specific
compounds
Conclusions:
Dietary
pregnancy
involved
pathogenesis,
exerting
either
an
exacerbating
or
protective
effect.
Improving
pregnant
women’s
dietary
habits
could
cost-effective
strategy
reduce
future
burden.
Epigenetic
mechanisms
can
influence
genes
at
the
transcriptional
and
post-transcriptional
levels
and/or
translational
post-translational
level.
The
fundamental
molecular
that
mediate
epigenetic
modulation
are
DNA
methylation,
histone
posttranslational
modification,
non-coding
RNA
regulation.
modifications
directly
cause
disease,
such
as
Beckwith
Weidemann
syndrome,
an
imprinting
disorder
caused
by
abnormal
methylation.
Environmental
exposures
lifestyle
behaviors,
from
prenatal
period
on,
seem
to
be
origin
of
diseases
diabetes,
cardiovascular
diseases,
obesity,
cancer.
Maternal
malnutrition
along
with
low-protein
diets
pre-implantation
late
lactation,
is
associated
onset
metabolic
in
adult
offspring,
which
mediated
modifications.
Recent
data
suggest
physical
fitness
might
exceed
its
beneficial
effect
beyond
individual
impact
offspring
health
through
trans-generational
Journal of Advances in Medicine and Medical Research,
Journal Year:
2023,
Volume and Issue:
35(20), P. 43 - 49
Published: Aug. 19, 2023
Background:
Epigenetic
analyzes
associated
with
maternal
and
child
nutrition
are
the
subject
of
several
studies
due
to
their
crucial
role
in
fetal
development.
Significant
changes
diet
during
gestational
period
or
even
puerperium
can
lead
metabolic
diseases
neuropsychiatric
disorders.
Aims:
The
present
study
sought
carry
out
a
systematic
review
such
interactions
pre-
post-pregnancy
periods.
Study
Design:
Systematic
review.
Methodology:
Bibliographic
research
was
used
as
method
data
were
obtained
from
VHL
information
portal
2017
2021.
Original
articles
published
last
6
years,
related
nutritional
impacts
on
epigenetic
mechanisms,
whether
women
postpartum
newborns,
included
this
study.
In
newborns.
Results:
Nine
that
met
selection
criteria
topic
selected.
Conclusion:
Based
study,
it
possible
understand
relationship
between
expression
order
promote
area
facilitate
understanding
various
genomic
origin.
