Stimuli-responsive biomedical polymeric films for tissue regeneration DOI Open Access
Zili Xu, Junjie Deng, Dan Gao

et al.

Microstructures, Journal Year: 2025, Volume and Issue: 5(3)

Published: April 23, 2025

Tissue damage poses a significant burden on patients’ daily lives and has long driven the search for effective clinical treatments. Recent decades have witnessed development of smart biomedical materials satisfying specific requirements such as irregular shapes dynamic microenvironments at defective sites. Stimuli-responsive polymeric films are well-positioned to play considerable role in exploitation next-generation biomaterials both soft hard tissue regeneration. These can be fabricated through diverse approaches engineered with versatile structures properties. Furthermore, responsive stimuli temperature, water, light, these exhibit well-designed functions shape adaption, controlled drug release, cell adhesion vivo , effectively improving In this work, we review recent advancements stimuli-responsive films, beginning introduction their fabrication methods. Subsequently, mechanisms discussed scrutinized terms structure property variations. An overview applications regeneration, including skin, cardiovascular, nerve, bone is provided. Finally, further discuss benefits limitations practical applications, proposing our expectations perspectives future films.

Language: Английский

Stimuli-responsive biomedical polymeric films for tissue regeneration DOI Open Access
Zili Xu, Junjie Deng, Dan Gao

et al.

Microstructures, Journal Year: 2025, Volume and Issue: 5(3)

Published: April 23, 2025

Tissue damage poses a significant burden on patients’ daily lives and has long driven the search for effective clinical treatments. Recent decades have witnessed development of smart biomedical materials satisfying specific requirements such as irregular shapes dynamic microenvironments at defective sites. Stimuli-responsive polymeric films are well-positioned to play considerable role in exploitation next-generation biomaterials both soft hard tissue regeneration. These can be fabricated through diverse approaches engineered with versatile structures properties. Furthermore, responsive stimuli temperature, water, light, these exhibit well-designed functions shape adaption, controlled drug release, cell adhesion vivo , effectively improving In this work, we review recent advancements stimuli-responsive films, beginning introduction their fabrication methods. Subsequently, mechanisms discussed scrutinized terms structure property variations. An overview applications regeneration, including skin, cardiovascular, nerve, bone is provided. Finally, further discuss benefits limitations practical applications, proposing our expectations perspectives future films.

Language: Английский

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