Journal of Oncology Pharmacy Practice,
Journal Year:
2023,
Volume and Issue:
unknown
Published: July 27, 2023
Autoimmune
side
effects
can
be
detected
during
the
use
of
BRAF/MEK
inhibitor.
Although
its
frequency,
mechanism
and
importance
are
not
known
exactly,
there
cases
reported
in
literature.We
report
a
case
drug-induced
vitiligo
patient
with
metastatic
conjunctival
malignant
melanoma
who
was
treated
inhibition
therapy.In
case,
controlled
topical
treatments.
Follow-up
process
has
been
continuing
no
progression
on
month
12
current
treatment.Although
ICI-related
autoimmune
have
described
more
frequently,
may
also
occur
secondary
to
BRAK/MEK
inhibition.
This
points
out
that
cutaneous
toxicity
is
manageable
delay
treatment
thanks
collaboration
dermatologists
oncologists.
Journal of Plastic Surgery and Hand Surgery,
Journal Year:
2021,
Volume and Issue:
55(6), P. 380 - 387
Published: March 26, 2021
Plantar
reconstruction
is
a
complex
procedure
due
to
the
paucity
of
tissue
around
foot.
Tissues
used
for
should
provide
similar
properties,
which
can
be
accomplished
by
using
ultra-thin
flaps.
Validated
functional
scales
may
essential
information
regarding
patients'
evolution.Information
concerning
series
12
cases
plantar
free
flaps
was
gathered
retrospectively
authors.
Data
from
preoperative
scores
in
Lower
Extremity
Functional
Scale
and
American
Orthopaedic
Foot
Ankle
Society
scale
were
obtained
clinical
records;
these
compared
postoperative
assigned
prospectively
during
follow-up.
Differences
determined
Student's
t-test
paired
samples.
Objective
measurements
evolution
(ulceration,
footwear
usage,
sensation),
as
well
patient
satisfaction,
also
explored.The
mean
follow-up
duration
16.5
(range
24)
months.
The
modified
39.1
60.2,
p
=
0.004;
42.2
53.4,
0.012.
No
showed
ulceration.
Protective
sensation
achieved
75%
patients,
10
out
could
use
regular
footwear.
All
patients
reported
satisfaction
with
surgical
procedure.Ultra-thin
foot
are
related
improvement
scales,
high
rates
limited
range
complications.
Our Dermatology Online,
Journal Year:
2021,
Volume and Issue:
12(e), P. 1 - 3
Published: Jan. 28, 2021
We
report
an
observation
of
a
good
prognosis
ungual
melanoma
showed
up
10
years
after
the
onset
generalized
vitiligo.
It’s
66ans
old
male,
with
history
rapidly
progressing
vulgar
vitiligo
earlier.
The
patient
has
been
referred
to
us
for
management
nail
melanoma,
retained
on
clinical
and
histological
data,
extended
70%
Body
Surface
Area.
assessment
locoregional
distant
extension
was
without
abnormalities.
Several
authors
have
reported
association
other
autoimmune
disorders,
non-melanoma
skin
cancers,
or
as
part
particular
syndrome.
ungueal
rarely
in
literature.
Across
this
observation,
we
illustrate
that
cutaneous
is
not
rare
may
be
factor
prognosis.
Journal of Oncology Pharmacy Practice,
Journal Year:
2023,
Volume and Issue:
unknown
Published: July 27, 2023
Autoimmune
side
effects
can
be
detected
during
the
use
of
BRAF/MEK
inhibitor.
Although
its
frequency,
mechanism
and
importance
are
not
known
exactly,
there
cases
reported
in
literature.We
report
a
case
drug-induced
vitiligo
patient
with
metastatic
conjunctival
malignant
melanoma
who
was
treated
inhibition
therapy.In
case,
controlled
topical
treatments.
Follow-up
process
has
been
continuing
no
progression
on
month
12
current
treatment.Although
ICI-related
autoimmune
have
described
more
frequently,
may
also
occur
secondary
to
BRAK/MEK
inhibition.
This
points
out
that
cutaneous
toxicity
is
manageable
delay
treatment
thanks
collaboration
dermatologists
oncologists.
