Updates in clinical dermatology, Journal Year: 2022, Volume and Issue: unknown, P. 191 - 202
Published: Jan. 1, 2022
Language: Английский
Journal of Cutaneous Medicine and Surgery, Journal Year: 2022, Volume and Issue: 26(5), P. 512 - 513
Published: May 19, 2022
Language: Английский
Citations
2
Zeitschrift für Rheumatologie, Journal Year: 2022, Volume and Issue: 81(7), P. 577 - 586
Published: July 19, 2022
Citations
2
Case Reports in Dermatological Medicine, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 5
Published: Nov. 18, 2022
Granuloma annulare (GA) is a benign skin disease that has four clinical variants including localized, generalized, perforating, and subcutaneous GA. The most common type localized GA, followed by generalized Generalized GA was defined as at least 10 widespread annular plagues frequently on the trunk, face, neck, extremities. diagnosis made histopathology. difficult to treat. Case Presentation. We presented Thai woman with nonscaly papules plaques trunk all A biopsy revealed lesion compatible granuloma annulare. She partially resolved 2-month course of oral griseofluvin 500 mg daily. Discussion. regression response griseofulvin consistent inflammatory nature, which identified IFN-gamma upregulated in GA.Griseofulvin safe few side effects cost effectiveness. Further studies are needed better understand immunology pathogenesis
Language: Английский
Citations
1
rheuma plus, Journal Year: 2023, Volume and Issue: 22(4), P. 210 - 219
Published: March 10, 2023
Citations
0
Nepal Journal of Dermatology Venereology & Leprology, Journal Year: 2023, Volume and Issue: 21(1), P. 10 - 13
Published: March 31, 2023
Introduction: The COVID-19 pandemic created a nation-wide lockdown with hospital services resorting only to the emergency sections. Dermatology out-patient was closed majority of being deferred for later date or through online platform. Here, we try find whether Nepalese dermatologists were contributing sciences research. Methods: A Google Scholar search using certain key words publications done by dermatologist during year 2020-2021 described as period. Similar conducted 2018-2019 same time frame called pre-pandemic. All analyzed appropriate statistical methods. Results: total 197 retrieved period compared 106 published articles in non-pandemic Among publications, 81 (41.11%) PubMed indexed journal 40 (37.73%) out earlier However, increase number not statistically significant. Conclusion: An interest among academic noted This might be due proper use and closure department.
Language: Английский
Citations
0
Indian Journal of Drugs in Dermatology, Journal Year: 2023, Volume and Issue: 9(1), P. 40 - 40
Published: Jan. 1, 2023
Language: Английский
Citations
0
Cureus, Journal Year: 2023, Volume and Issue: unknown
Published: Oct. 24, 2023
Granuloma annulare (GA) is characterized by palisading granuloma, which histopathologically distinguished histiocytes arrayed in a palisade configuration encircling insoluble entities associated with degenerated collagen fibrils. The present case demonstrated multiple cutaneous papules showing granuloma patient SLE. A 39-year-old woman has been taking oral prednisolone daily, hydroxychloroquine sulfate, and belimumab for systemic lupus erythematosus (SLE). few appeared on the lateral side of left arm gradually increased around both sides. Physical examination found firm skin-colored ranging diameter from 2 to 3 mm forearms. Some had umbilicated tops. Histopathological showed fibers mucin deposition surrounded histiocyte infiltrates dermis. These findings are characteristic granuloma. There several GA variants, such as generalized, subcutaneous, perforating GA. We considered possibilities mechanisms underlying histological changes; atypical generalized dermatofibroma, vasculitis. made final diagnosis papular context
Language: Английский
Citations
0
Acta Dermato Venereologica, Journal Year: 2023, Volume and Issue: 103, P. adv18855 - adv18855
Published: Dec. 20, 2023
Abstract is missing (Short communication)
Language: Английский
Citations
0
American Journal of Dermatopathology, Journal Year: 2022, Volume and Issue: 44(8), P. 618 - 620
Published: April 11, 2022
To the Editor: Interstitial granulomatous dermatitis (IGD) is a rare disorder first reported with arthritis.1 Its pathognomonic sign, rope linear prominent cutaneous band on trunk. Subsequent accumulation of cases has shown that IGD rarely shows sign; moreover, its association arthralgia or arthritis not always found, and approximately half have autoantibodies.2 Histologic features comprise collagen degeneration associated dermal band-like infiltrate composed mainly histiocytes.3 Neutrophils eosinophils are also present in infiltrate; however, usually no vasculitis seen.3 In this study, we report case neutrophilic infiltrate. A 60-year-old woman presented 3-year history asymptomatic eruption left lateral trunk, which developed right trunk 1 month before. The patient experienced idiopathic thrombocytopenic purpura (ITP) for 13 years, was well-controlled mg prednisolone every 10 days normal platelet count. physical examination revealed erythematous bands bilateral (Fig. 1). Biopsy performed lesion it reticular mixed inflammatory infiltrates centered hyalinized degenerated bundles histiocytes 2). Dense perivascular lymphocytic surrounded 2A). Alcian blue colloidal iron stains did reveal mucin deposition. No neutrophils, frank vasculitis, granuloma formation identified. Based typical clinical sign histopathologic findings, diagnosed IGD. Although further investigation positive anti-SSA anti–double-stranded DNA autoantibodies, showed symptoms any vascular diseases. became slightly dark reddish because potent topical corticosteroids; nonetheless, remained stable 1.5 years.FIGURE 1.: B, Linear trunk.FIGURE 2.: A, Degenerated were by dense mid deep dermis [hematoxylin–eosin (HE), original magnification ×20]. histiocytes. Neutrophilic recognized (HE, ×200). C D, CD68 staining highlighted an increased number [CD68, (C) ×20, (D) ×200].IGD histopathologically characterized lesions showing interstitial lymphocytes, surrounding foci neutrophils eosinophils.4 Vasculitic changes absent, deposits minimal absent. Coutinho et al4 studied IGD, all mild, moderate, heavy We hesitated to make diagnosis However, manifestation suggested realized occasionally absent Verneuil al3 asserted findings differ according stage at time biopsy. Early-stage show pandermal infiltrate, whereas fully scattered leukocytes.3 This may be end considering lack often confused palisaded (PNGD), exhibits larger basophilic eosinophilic more infiltrates, without leukocytoclastic vasculitis.4 Mucin scant PNGD similar manifestations, including plaques/macules, annular plaques, papules/nodules.2 both diseases.2 Some studies suggest overlapping disease entities continuum based PNGD.2,5 Regarding PNGD, Chu al6 early-stage diffuse diminished older neutrophils. Taken together, abundant early decrease course eventually depleted. been described less than 10% patients autoimmune disorders.2 ITP never as PNGD. Because patient's when developed, possibility coincidental cannot denied. disappear within few weeks, persist over years rest despite various treatments.2 refractory treatment. Refractory absence such long course. Other differential diagnoses annulare (GA) drug eruption. low-power view our similarity pattern, GA denied increase mucin.7 According recent review GA, GA.7 relatively normal-appearing scanning magnification, slight cellularity.7 case, so. caused specific drugs angiotensin-converting enzyme inhibitors, anticonvulsants, antidepressants, antihistamines, anti-tumor necrosis factor agents, beta-blockers, diuretics, herbal medications, immune checkpoint lipid-lowering agents.8 treated gastric-coating agent vitamin D3 preparation, addition, interface reaction detected dermoepidermal junction presence characteristic feature eruption.9
Language: Английский
Citations
0
Therapies, Journal Year: 2022, Volume and Issue: 78(4), P. 457 - 459
Published: Sept. 27, 2022
Language: Английский
Citations
0