Profiling of Various Dry Cannabis Sativa From Aceh, Indonesia Based on Cannabinoids Compound Characteristics
Abstract
Background
Cannabis,
which
is
a
narcotic
plant,
refers
to
the
leaves,
flowers,
stems,
and
seeds.
Cannabis
used
globally
for
its
psychoactive
properties
with
2.5%
of
world's
population
consuming
it
for.
In
Indonesia,
plant
classified
as
Class
1
prevalence
use
reaching
41.4%.
Aceh
one
largest
cannabis
producing
regions
in
due
favorable
geographical
climatic
conditions.
Despite
illegal
status,
contains
valuable
phytocannabinoid
compounds
potentially
important
medical
applications.
Previous
studies
have
shown
correlation
between
compound
profile
origin.
This
study
aims
develop
classification
method
based
on
cannabinoids
profiles
dried
samples
taken
from
five
(Aceh
Besar,
Tengah,
Bireuen,
Lhokseumawe,
Pidie
Jaya),
by
microscopy,
raman
spectrophotometry,
GC-MS,
parametric
statistical
analysis
assist
authorities
tracing
source
law
enforcement
forensic
purposes.
Results
In
this
study,
sativa
Aceh,
was
tested
Raman
spectroscopy
GC-MS
produce
informative
cannabinoid
profiling.
The
results
obtained
10
quantified
(Δ9-THC,
CBD,
THCV,
CBL,
CBTC,
Methoxy-THC,
CBC,
CBG,
Δ9-THCH,
CBN).
showed
Δ9-THC
had
highest
overall
content
indicated
most
clustering
profile.
Among
various
regions,
Besar
content.
Statistical
data
found
(1)
revealed
responsible
cultivars
clusters,
(2)
variation
among
chemical
result
growing
environment,
(3)
facilitated
prediction
helping
categorize
unknown
origin
profiles.
Conclusion
Raman
proven
reliable
efficient
methods
classifying
Indonesia.
findings
help
reveal
location
specimens.
All
contained
major
constituent.
comes
AB
influence
environmental
factors.
Parametric
test
concluded
that
there
no
significant
effect
geog
raphical
related
relatively
close
distance
range
samples.
Additionally,
comparing
these
other
analytical
techniques
will
support
defined
models
improve
their
application
science,
particularly
drug
quality
assessment.
Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown
Published: April 2, 2025
Language: Английский