Journal of Clinical Medicine,
Journal Year:
2023,
Volume and Issue:
13(1), P. 3 - 3
Published: Dec. 19, 2023
The
progressive
aging
and
comorbidities
of
the
population
have
led
to
an
increase
in
number
patients
with
polypharmacy
attended
emergency
department.
Drug-related
problems
(DRPs)
become
a
major
cause
admission
these
units,
as
well
high
rate
short-term
readmissions.
Anticoagulants,
antibiotics,
antidiabetics,
opioids
been
shown
be
most
common
drugs
involved
this
issue.
Inappropriate
has
pointed
out
one
causes
visits.
Different
ways
conducting
chronic
medication
reviews
at
discharge,
primary
care
coordination,
phone
contact
discharge
reduce
new
hospitalizations
room
visits
due
DRPs,
they
are
key
elements
for
improving
quality
provided
by
services.
Drug Safety,
Journal Year:
2024,
Volume and Issue:
47(9), P. 829 - 839
Published: June 17, 2024
In
2022,
the
network
refreshed
its
purpose
to
encompass
larger
scope
of
safe
and
appropriate
use
medications
for
Canadians
all
ages
hence
was
renamed
Canadian
Medication
Appropriateness
Deprescribing
Network
(CADeN).In
2023,
CADeN,
with
expanded
scope,
united
key
players
once
more
build
a
structured,
pan-Canadian
movement
promote
medication
appropriateness
people
ages.This
event
funded
by,
held
in
partnership
with,
Health
Canada.
Attendance
Goals
National
Meeting
AttendanceThe
CADeN
2023
on
8
9
November
Montreal,
QC,
Canada,
hosting
101
attendees.Attendees
included
public
members,
community
leaders,
healthcare
providers,
organization
leaders
appropriateness,
researchers,
trainees,
policy
makers
from
10
13
provinces
territories,
along
international
experts
invited
USA
Australia.Among
government
representatives
attending
were
members
Drug
Agency
Transition
Office
(CDATO).The
Government
Canada
launched
CDATO
spring
2021,
work
provinces,
stakeholders
vision,
mandate,
plan
establish
(CDA)
that
would
improve
pharmaceutical
system
coordination
support
related
work.This
supported
by
Budget
2019
investment
$35
million
CAD
over
4
years
[20].As
primary
stakeholder
CDATO,
working
partner
Meeting.Members
encouraged
host
consultations
attendees
help
guide
development
CDA
strategy
supporting
prescribing
Canada.The
aimed
incorporate
principles
equity,
diversity,
inclusion
among
scientific
organizing
committee,
keynote
speakers,
presenters,
representation
early
career
as
well
voices
lived
experience.
AIDS,
Journal Year:
2024,
Volume and Issue:
38(13), P. 1819 - 1828
Published: June 20, 2024
This
study
aims
to
estimate
the
extent
which
anticholinergic
and
sedative
burden
is
associated
with
cognitive
ability
self-reported
difficulties
(SCD)
in
middle-aged
older
adults
living
HIV.
AIDS,
Journal Year:
2023,
Volume and Issue:
38(4), P. 509 - 519
Published: Dec. 1, 2023
Objective:
This
study
aimed
to
estimate
the
strength
of
association
between
anticholinergic/sedative
burden
and
concurrent
physical
frailty
in
people
aging
with
HIV.
Design:
cross-sectional
analysis
examined
baseline
data
from
824
adults
a
mean
age
53
enrolled
Positive
Brain
Health
Now
study.
Methods:
Anticholinergic
medications
were
identified
using
four
methods:
Cognitive
Burden
(ACB)
Scale,
Risk
Scale
(ARS),
Drug
(ADS),
anticholinergic
list
Sedative
Catalog
(ACSBC).
Sedatives
Load
Model
(SLM)
sedative
ACSBC.
Physical
was
assessed
modified
Fried
Frailty
Phenotype
(FFP)
based
on
self-report
items.
Multivariable
logistic
regression
models,
adjusted
for
sociodemographic
factors,
lifestyle
considerations,
HIV-related
variables,
comorbidities,
co-medication
use,
used
odds
ratios
(ORs).
Results:
demonstrated
associations
across
various
total
(OR
range:
1.22–1.32;
95%
confidence
interval
(CI)
1.03–1.66),
1.18–1.24;
CI
1.02–1.45),
high
2.12–2.74;
1.03–6.19),
1.94–2.18;
CI:
1.01–4.34).
Conclusion:
The
burdens
may
represent
modifiable
risk
factors
Future
studies
should
evaluate
effects
reducing
outcomes
explore
prognostic
value
diverse
scoring
methods.
Therapeutic Advances in Drug Safety,
Journal Year:
2024,
Volume and Issue:
15
Published: Jan. 1, 2024
Numerous
studies
report
that
anticholinergic
burden
(ACB)
has
been
linked
with
several
health
consequences,
including
increased
hospital
admissions,
prolonged
hospitalization,
and
physical
cognitive
impairment.
However,
low-
middle-income
settings,
as
well
younger
individuals,
are
underrepresented.
