Mountains of research: Where and whom high‐altitude physiology has overlooked DOI Creative Commons
Joshua C. Tremblay

The Journal of Physiology, Journal Year: 2023, Volume and Issue: 602(21), P. 5409 - 5417

Published: Dec. 8, 2023

Abstract High altitude is a natural setting in which to study human acclimatization and adaptation. Here, I identify where whom high‐altitude physiology research has occurred. There been mismatch between countries with large populations vs . conducted. From 1970 2020, 83% of took place just seven countries: Nepal, China, USA, Peru, India, Bolivia Italy. Collectively, these account for only 35% the global population living above 2500 m. Furthermore, predominantly studied low‐altitude residents visiting high female participants are under‐represented. Accordingly, included not necessarily proportional representation residents. discuss how this influences our understanding Finally, highlight past initiatives increase diversity research. By identifying broad gaps research, propose exciting, inclusive opportunities physiology. image

Language: Английский

Consumption of Mixed Indigenous Vegetables: A solution to low hemoglobin levels among pregnant women in Babati, Tanzania DOI Open Access

Zacharia Malley,

Elingarami Sauli, Haikael Martin

et al.

Current Research in Nutrition and Food Science Journal, Journal Year: 2025, Volume and Issue: 13(1), P. 494 - 507

Published: March 25, 2025

Pregnancy-related anemia is a critical health issue affecting larger number of pregnant women in Tanzania affected. The study examined the impact consuming locally grown indigeneous vegetables on iron intake and prevention. utilized cross-sectional design to investigate indigenous prevention among 340 Babati District, Tanzania. Participants were recruited from antenatal care services at four facilities within district. Dietary assessments conducted evaluate food consumption patterns Diversity Scores (DDS).were calculated determine variety groups consumed. Indigenous analyzed for iron, vitamin C, phytate content assess their nutritional composition. Statistical analyses included Chi2 (χ2) tests Spearman rank correlations relationships between socio-demographic factors, dietary practices, prevalence. prevalence was 45%, with significant association maternal age (P < 0.04, χ2 = 6.43), as older (36–49 years) less likely be anemic compared younger (≤35 years). Marital status also correlated 4.1), married showing lower diversity limited, only 55.6% participants five or more (DDS ≥ 5). vegetables, such sweet potato leaves amaranth combined lemon juice, showed high C (43.2 ± 0.26 mg/g), enhancing absorption. Hygiene practices like hand washing after toilet use associated reduced risk 0.0022, 9.352). This highlights importance diversity, good hygiene reducing rural Tanzania, emphasizing need nutrition education improved access iron-rich foods.

Language: Английский

Citations

0
High altitude marathon physiology changes DOI Open Access

Medha Oak,

Ajit Oak,

Bageshree Oak

et al.

International Journal of Advances in Medicine, Journal Year: 2025, Volume and Issue: 12(3), P. 333 - 339

Published: April 24, 2025

High-altitude marathons present unique physiological challenges due to environmental factors such as reduced oxygen availability, decreased atmospheric pressure, and extreme temperature fluctuations. These conditions impose significant stress on the human body, requiring acute chronic adaptations maintain performance. Acute responses include increased ventilation, elevated heart rate, enhanced delivery mechanisms, while involve hematological changes erythropoiesis, cardiovascular remodeling, skeletal muscle adaptations. Despite these adaptations, high-altitude can substantially impact athletic performance, reducing aerobic capacity increasing risk of hypoxia-induced fatigue. Effective training acclimatization strategies, altitude camps pre-acclimatization protocols, are critical for optimizing performance minimizing risks illnesses, including mountain sickness (AMS), pulmonary edema (HAPE), cerebral (HACE). Furthermore, genetic predispositions, observed in native populations, may influence an athlete's ability adapt environments. This review explores interplay between challenges, marathons. It highlights current strategies preparation, potential medical risks, future research opportunities understanding demands endurance events. Insights from this study aim guide athletes, coaches, professionals training, safety during

Language: Английский

Citations

0
Impact of menopause on responses to hypoxia and incidence of acute mountain sickness DOI Creative Commons
Tom Citherlet, Antoine Raberin, Giorgio Manferdelli

et al.

European Journal of Applied Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Language: Английский

Citations

0
The menstrual cycle minimally affects cardiorespiratory function and body balance control in trained women during acute hypobaric hypoxia exposure (4000 m) DOI Creative Commons
Cristina Rotllan,

Jan Hagenaers,

M Colls

et al.

European Journal of Applied Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 30, 2025

Language: Английский

Citations

0
Sex-Specific Cardiac Adaptation to Chronic Hypoxia in High-Altitude Dwellers: Quantitative Insights from 3.0T Cardiovascular Magnetic Resonance DOI Open Access

Ya Shen,

Jianjun Zhang,

Chunyang Cai

et al.

Open Journal of Medical Imaging, Journal Year: 2025, Volume and Issue: 15(02), P. 79 - 88

Published: Jan. 1, 2025

Language: Английский

Citations

0
Combined effects of normobaric hypoxia and cold on respiratory system responses to high‐intensity exercise DOI Creative Commons
Alexa Callovini, Alessandro Fornasiero, Aldo Savoldelli

et al.

Experimental Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: May 11, 2025

Abstract Cold temperatures (<−15°C) increase exercise‐induced bronchoconstriction (EIB), while hypoxic‐induced hyperventilation exacerbates respiratory muscle fatigue for a given exercising task. This study aimed to determine the individual and combined effects of cold normobaric hypoxia on system responses high‐intensity exercise. Fourteen trained male runners (: 64 ± 5 mL/kg/min) randomly performed an incremental cardiopulmonary exercise test (CPET) volitional exhaustion under four environmental conditions: normothermic (18°C) normoxia 20.9%) 13.5%), (−20°C) hypoxia. Ventilatory during lung function (LF), maximal inspiratory (MIP) expiratory (MEP) pressure measurements before after were evaluated. Volume air forcefully exhaled in 1 s (FEV1), FEV1/forced vital capacity (FVC), peak flow, forced flow mid (25–75%) portion FVC, at 50% FVC affected by exposure. No significant pre‐ post‐exercise change MIP MEP was found, independent conditions. Greater LF impairments cold‐normoxia coldhypoxia associated with lowest ventilatory exposure found negatively impact LF, further highlighting relationship between EIB presence blunted response cold. Respiratory strength remained unchanged regardless condition, suggesting no detrimental effect this parameter when intermittent short‐duration exercises are performed. Future studies should investigate cold‐hypoxic longer durations sustained high intensity, accounting differences hypobaric exposures.

Language: Английский

Citations

0
High‐level performances following low altitude training and tapering in warm environments in elite racewalkers DOI Creative Commons
Bastien Krumm,

Brent Vallance,

Louise M. Burke

et al.

European Journal of Sport Science, Journal Year: 2024, Volume and Issue: 24(8), P. 1120 - 1129

Published: July 11, 2024

Abstract Current guidelines for prolonged altitude exposure suggest levels ranging from 2000 to 2500 m optimize an increase in total hemoglobin mass (Hbmass). However, natural low locations (<2000 m) remain popular, highlighting the interest investigate any possible benefit of camps endurance athletes. Ten elite racewalkers (4 women and 6 men) underwent a 4‐week “live high‐train high” (LHTH) camp at 1720 (P I O 2 = 121 mmHg; 20.1°C; 67% relative humidity [RH]), followed by 3‐week tapering phase (20 m; P 150 28.3°C; 53% RH) preparation World Athletics Championships (WC). Venous blood samples were withdrawn weekly during entire observation period. In addition, volumes determined carbon monoxide rebreathing weeks after return sea level. High‐level performances achieved WC (five placings among Top 10 races three all‐time career personal bests). A slight but significant absolute (+1.7%, p 0.03) Hbmass (+2.3%, 0.02) was observed LHTH. as usually LHTH protocols, training distance (+28%, duration (+30%, 0.04) significantly increased compared pre‐LHTH Therefore, although direct causation cannot be inferred, these results that combination load altitudes with subsequent period warm environment is suitable competition‐preparation strategy

Language: Английский

Citations

3
Fitness Level– and Sex-Related Differences in Pulmonary Limitations to Maximal Exercise in Normoxia and Hypoxia DOI Creative Commons
Antoine Raberin, Giorgio Manferdelli,

Forrest Schorderet

et al.

Medicine & Science in Sports & Exercise, Journal Year: 2024, Volume and Issue: unknown

Published: March 25, 2024

Both maximal-intensity exercise and altitude exposure challenge the pulmonary system that may reach its maximal capacities. Expiratory flow limitation (EFL) exercise-induced hypoxemia (EIH) are common in endurance-trained athletes. Furthermore, because of their smaller airways lung size, women, independently fitness level, be more prone to limitations during exercise, particularly when performed hypoxic conditions. The objective this study was investigate impact sex level on normoxia consequences acute hypoxia.

Language: Английский

Citations

2
Women Upward—Sex Differences in Uphill Performance in Speed Climbing, Ski Mountaineering, Trail Running, Cross-Country Skiing, and Cycling DOI
Grégoire P. Millet, Antoine Raberin, Raphaël Faiss

et al.

International Journal of Sports Physiology and Performance, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 10

Published: Jan. 1, 2024

Introduction : Women have generally lower body size and lean- to fat-mass ratio, maximal anaerobic power due a muscle mass, fewer fast-twitch fibers, although they can show higher resistance fatigue or greater metabolic flexibility than men. These factors are well known explain the sex differences in endurance sports such as distance running (10%–12%). Several of these factors—particularly composition skeletal-muscle characteristics—may directly impact vertical displacement uphill performance. However, there is lack sex-difference reports with locomotion. Methods The world-level performance over 10 years (2013–2022) 6 different (speed climbing, race ski mountaineering, kilometer mountain running, cycling, cross-country skiing, ultratrail running) were calculated. Results larger (18%–22%) performed primarily on flat terrains. This may be ratio commonly reported women. In shorter events (eg, sport kilometer, short climb cycling), appear even more pronounced (28%–35%), potentially being explained by additional capacity, composition, upper-body contribution). Conclusion novel analysis elite shows that

Language: Английский

Citations

2
Intermittent Hypoxic Training Increases and Prolongs Exercise Benefits in Adult Untrained Women DOI
Alba Camacho-Cardeñosa, Marta Camacho-Cardeñosa, Johannes Burtscher

et al.

High Altitude Medicine & Biology, Journal Year: 2024, Volume and Issue: unknown

Published: May 8, 2024

Alba Camacho-Cardenosa, Marta Johannes Burtscher, Pedro R. Olivares, Guillermo Olcina, and Javier Brazo-Sayavera. Intermittent hypoxic training increases prolongs exercise benefits in adult untrained women. High Alt Med Biol. 00:00–00, 2024.

Language: Английский

Citations

1