Frontiers in Psychiatry,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 20, 2024
Background
Incidence
rates
of
autism,
attention-deficit/hyperactivity
disorder
(ADHD),
and
gender
dysphoria
(GD)
are
rising
not
only
in
the
general
population,
but
particularly
among
children,
adolescents,
young
adults
with
eating
disorders
(EDs).
While
ED
have
risen
during
COVID
pandemic,
trends
co-occurring
ADHD,
GD
yet
to
be
investigated
detail
or
at
scale
by
way
large
electronic
medical
record
data.
Objectives
To
investigate
EDs
years
prior
COVID-19
pandemic.
Methods
We
utilized
a
de-identified
multinational
health
records
database
(TriNetX)
48,558
individuals
aged
5-26
diagnosed
(EDs)
least
twice
between
2017
2022.
The
primary
predictor
variable
differentiated
each
person’s
index
(first)
diagnosis
(2017-2019
vs.
2020-2022).
outcome
was
rate
new
psychiatric
diagnoses
year
following
patient’s
first
diagnosis.
applied
propensity
score-matched
multivariable
logistic
regressions
compare
outcomes
2017-2019
2020-2022.
Results
Our
analysis
included
17,445
(8%
13.5%
1.9%
GD)
31,113
2020-2022
14.6%
3.2%
GD).
After
1:1
score
matching,
17,202
from
cohort
were
matched
peers
mirroring
cohort.
Those
showed
19%
(aOR[95%CI]=1.19[1.07-1.33]),
25%
(aOR=1.25[1.04-1.49]),
36%
(aOR=1.36[1.07-1.74])
increase
odds
for
diagnoses,
respectively,
within
365
days
after
diagnosis,
compared
Discussion
Rates
significantly
higher
post-pandemic
comparison
pre-pandemic
cohort,
even
controlling
baseline
levels
diagnoses.
Such
findings
reveal
critical
gap
our
current
understanding
totality
ways
which
may
impacted
onset
clinical
course
EDs,
adults.
