Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Relationship between multimorbidity, SARS-COV-2 infection and long COVID: a cross-sectional population-based French survey DOI Creative Commons
Tatjana T. Makovski, O. Steichen,

Melissa Rushyizekera

et al.

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 15, 2025

Understanding the risks of COVID-19-related consequences for vulnerable groups such as people with multimorbidity is crucial to better tailor health care and public measures. The main objective this study was explore association between WHO-defined post-COVID condition (PCC), while also considering SARS-COV-2 infection given that a prerequisite PCC. This population-representative cross-sectional conducted in general adult population mainland France 29 August 31 December 2022 (N = 1813). analyses (defined disease count most prevalent dyads/triads) PCC or SAR-COV-2 were adjusted age, sex, socioeconomic variables number infections (for only) using Poisson regression robust variance. had mean age (SD) 53 (± 18.5) years, 53.6% women. likelihood increased but only significant ≥ 4 diseases. Five dyads one triad presented higher risk; almost all included anxiety. count, prevalence ratios (PRs) (95% CI) 1, 2-3 diseases versus 0 1.90 (1.16-3.13), 3.32 (2.07-5.35) 5.65 (3.41-9.38), respectively, 19 26 triad. strongest cardiac rhythm disorder either low back pain (PR (95%CI) 4.17 (2.03-8.53)) anxiety 3.73 (1.98-7.01)). Multimorbidity, frequently combination pain, beyond SARS-CoV-2 underscoring importance implementing strategies prevent manage persistent symptoms groups.

Language: Английский

Citations

0
The role of socio-economic determinants in SARS-CoV-2 health outcomes: systematic review of population-based studies. DOI Open Access
Jinane Ghattas, Tatjana T. Makovski, Stéphanie Monnier-Besnard

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 19, 2024

Introduction: The COVID-19 pandemic has accentuated a health-wealth gradient, reminiscent of patterns observed in previous influenza pandemics. This systematic review, employing population-based approach, aims to delve into the etiological and prognostic roles socio-economic factors on outcomes during pandemic's initial phase. Methods: Our search spanned PubMed, Embase, WHO Global literature, PsycINFO databases from January 2020 April 7, 2021, focusing English peer-reviewed articles. We examined impact determinants SARS-CoV-2 infection, related hospitalization, ICU admission, mechanical ventilation, mortality, range including quality life mental health. Results: resulted 9,701 records after removal duplicates. Out hundred articles that met our review criteria, 67 discussed role factors, 25 addressed role, 8 covered both. Fifty-nine percent studies were United States America Kingdom, highlighting an increased risk infection severity among their Black, Asian, Hispanic populations. Lower-income groups, crowded households, and, higher deprivation associated with incidence severity. Results regarding educational status varied across different waves. Conclusion: Populations groups disadvantaged positions certain ethnic racial backgrounds face poorer outcomes. findings underscore need for incorporating social routine health surveillance monitoring, suggesting avenue targeted interventions.

Language: Английский

Citations

0
The Impact of Comorbidity and Age on the Risk of Hospitalization and Mortality in Patients with Previous COVID-19 Infection—Based on Nationwide Data DOI Open Access
Ken Lund, Jan Nielsen, Simon Kjeldsen

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(21), P. 6522 - 6522

Published: Oct. 30, 2024

: The influence of comorbidity on long-term hospitalization and mortality after COVID-19 in adults (40-59 years) older (≥60 is yet to be explored.

Language: Английский

Citations

0
Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Citations

0