Distinctive But Not Exceptional: The Risks of Psychedelic Ethical Exceptionalism
The American Journal of Bioethics,
Journal Year:
2025,
Volume and Issue:
25(1), P. 16 - 28
Published: Jan. 2, 2025
When
used
clinically,
psychedelics
may
appear
unusual
or
even
unique
when
compared
to
more
familiar
long-standing
medical
interventions,
prompting
some
suggest
that
the
ethical
issues
raised
likewise
be
exceptional.
If
is
correct,
then
perhaps
should
treated
differently
from
other
substances:
for
example,
by
being
subjected
different
evidentiary
standards.
Alternatively,
it
have
in
common
with
various
existing
interventions
than
first
meets
eye.
We
argue
favor
of
latter
position,
drawing
on
parallels
earlier
debates
around
genetic
exceptionalism
bioethics.
there
are
risks
adopting
a
stance
"psychedelic
exceptionalism,"
and
propose
consistent
rules
standards
applied
across
all
relevant
areas
clinical
medicine.
Importantly,
this
does
not
preclude
possibility
changes
made;
but
if
so,
justified
appealing
alleged
uniqueness
psychedelics.
Language: Английский
Exploring factors associated with the intensity of a mystical experience following naturalistic psychedelic use: A retrospective survey
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 111300 - 111300
Published: Feb. 1, 2025
Language: Английский
Race and Gender Differences in the Moderating Relationship of Psychedelics on Stigma and Distress
Psychedelic Medicine,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 22, 2025
Language: Английский
Minorities’ diminished psychedelic returns: Depression, suicide, distress, and serious mental illness
Drug Science Policy and Law,
Journal Year:
2025,
Volume and Issue:
11
Published: April 1, 2025
Although
there
is
growing
support
for
the
protective
effects
of
psychedelics
on
mental
health,
recent
evidence
finds
racial
and
ethnic
minorities
gain
fewer
benefits.
This
paper
aims
to
test
whether
disparate
health
outcomes
associated
with
psychedelic
use
extend
across
multiple
groups,
including
non-Hispanic
Whites,
Blacks,
Asians,
Hispanics.
In
order
understand
relationship
between
race/ethnicity,
psychedelics,
this
study
draws
from
National
Survey
Drug
Use
Health
(NSDUH)
data
2005
2019,
a
sample
size
596,187
individuals.
The
examines
association
various
(such
as
MDMA,
Psilocybin,
DMT,
Ayahuasca,
Peyote/Mescaline,
LSD)
one
measure
Lifetime
Classic
Psychedelics
(LCPU)
measures,
depression,
suicidal
ideation,
suicide
planning,
attempts,
psychological
distress,
serious
illness.
Additionally,
analysis
compares
A
series
nested
logistic
ordinary
least
square
regression
models
are
used
in
analysis,
conducted
using
Stata
18.
results
reveal
significant
variation
outcomes.
Most
notably,
more
instances
where
better
among
Whites
compared
minority
populations.
Moreover,
not
only
associations
Black,
Hispanic,
Asian
individuals,
but
also
just
many
worse
particularly
Black
Language: Английский
Association between lifetime hallucinogen use and psychological distress varies by sexual identity in a nationally representative sample
Journal of Psychopharmacology,
Journal Year:
2024,
Volume and Issue:
38(10), P. 861 - 872
Published: Sept. 23, 2024
Background:
Clinical
trials
demonstrate
that
psychedelic-assisted
therapy
can
improve
mental
health
outcomes;
however,
few
studies
have
recruited
sexually
diverse
samples
or
reported
information
on
sexual
identity.
Aims:
The
purpose
of
this
analysis
was
to
examine
the
relationship
between
hallucinogen
use
and
outcomes
with
respect
Methods:
We
conducted
a
cross-sectional
using
data
from
2021
National
Survey
Drug
Use
Health
psychological
distress.
Results:
In
sample
representative
253,824,662
U.S.
adults,
majority
heterosexual
(92%),
aged
50–64
(25%),
women
(51%),
non-Hispanic
White
(62%),
college
educated
(31%),
had
an
annual
household
income
$75,000
higher
(39%).
no
lifetime
(82%)
past
month
severe
distress
(93%).
Sexual
identity
modified
After
stratifying
by
adjusting
for
covariates,
associated
reduced
odds
in
population
(OR
=
0.76,
95%
CI:
0.59,
0.96)
but
not
significant
minority
population.
Conclusion:
found
nationally
sample,
psychedelic
individuals
only.
Future
research
should
investigate
why
protective
groups
given
their
disproportionate
burden
poor
outcomes.
Language: Английский
Race/ethnicity moderates the associations between lifetime psilocybin use and opioid use disorder
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(5), P. e0321461 - e0321461
Published: May 7, 2025
Background:
Opioid
use
disorder
(OUD)
is
a
debilitating
health
condition
that
associated
with
significant
morbidity
and
mortality
in
the
U.S.
While
preliminary
studies
have
demonstrated
psilocybin
lowered
odds
of
OUD,
current
research
this
domain
suffers
from
lack
investigation
into
impact
race/ethnicity
on
association.
Objective:
To
assess
race
ethnicity
association
between
OUD
using
data
National
Survey
Drug
Use
Health
(2002–2019)
(N
=
706,891).
Method:
I
used
survey-weighted
multivariable
logistic
regression
to
test
whether
moderates
OUD.
Subsequently,
stratified
my
sample
by
assessed
associations
for
individual
racial
ethnic
groups
(White,
Black,
Indigenous,
Asian,
Multiracial,
Hispanic).
My
analysis
plan
was
pre-registered.
Results:
Race
significantly
moderated
Furthermore,
when
ethnicity,
only
White
participants
Hispanic
link
(White
aOR:
0.84;
0.68).
For
Multiracial
participants,
did
not
share
Conclusion:
moderate
Future
longitudinal,
experimental,
qualitative
needed
better
understand
pattern
observed
study.
Language: Английский
The Relationships Between Healthcare Access, Gender, and Psychedelics and Their Effects on Distress
Healthcare,
Journal Year:
2025,
Volume and Issue:
13(10), P. 1158 - 1158
Published: May 16, 2025
Background:
Structural
inequalities
in
healthcare
access
may
influence
how
individuals
experience
the
psychological
effects
of
psychedelic
substances,
potentially
limiting
positive
outcomes
among
vulnerable
populations.
Objectives:
This
study
uses
data
from
National
Survey
on
Drug
Use
and
Health
(2008-2019;
N
=
484,732)
to
examine
public
private
health
insurance
moderate
association
between
use
distress.
Methods:
Ordinary
least
squares
(OLS)
regression
models
indicate
that
is
associated
with
lower
distress,
while
higher
Results:
Psychedelic
moderates
these
associations,
reinforcing
protective
pattern
linked
intensifying
distress
those
coverage.
These
patterns
vary
by
gender:
men,
does
not
significantly
alter
type
distress;
women,
however,
psilocybin
lysergic
acid
diethylamide
(LSD)
are
insurance,
but
insurance.
Conclusions:
findings
psychedelics
interact
existing
conditions,
they
do
mitigate
structural
may,
some
cases,
exacerbate
them.
Language: Английский
Religious Social Integration, Psychedelics, and Psychological Distress
Journal of Psychoactive Drugs,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 12
Published: Nov. 7, 2024
Psychedelic
use
has
been
increasingly
accepted
socially
and
legally.
However,
there
is
a
gap
in
understanding
how
religion
can
influence
the
relationship
between
psychedelics
mental
health.
This
study
aims
to
explore
this
by
examining
impact
of
lifetime
classic
psychedelic
(LCPU),
religious
attendance,
salience
on
monthly
psychological
distress,
using
K6
scale.
The
data
for
project
sourced
from
National
Survey
Drug
Use
Health
(NSDUH)
2008
2019,
with
sample
size
458,372.
analysis
utilizes
several
Ordinary
Least
Square
regression
models
conducted
Stata
17.
results
indicate
that
both
are
associated
lower
levels
distress.
While
increased
linked
reduced
effect
weakened
use,
as
higher
distress
among
individuals
who
have
used
psychedelics.
three-way
interaction
reveals
high
attendance
experience
lowest
Language: Английский