Selective molecular characterization of organic aerosols using in situ laser desorption ionization mass spectrometry DOI

Daohe Yuan,

Yulin Qi, Chao Ma

et al.

Rapid Communications in Mass Spectrometry, Journal Year: 2024, Volume and Issue: 38(16)

Published: June 18, 2024

Rationale The sources and chemical compositions of organic aerosol (OA) exert a significant influence on both regional global atmospheric conditions, thereby having far‐reaching implications environmental chemistry. However, existing mass spectrometry (MS) methods have limitations in characterizing the detailed composition OA due to selective ionization as well fractionation during cold‐water extraction solid‐phase (SPE). Methods A comprehensive MS study was conducted using samples collected dusty, clean, polluted days. To supplement data obtained from electrospray (ESI), strategy for analyzing OAs quartz fiber filter directly utilizing laser desorption (LDI) employed. Additionally, ESI method explore suitable approaches determining various Results In situ LDI has advantages significantly reducing sample volume, simplifying preparation, overcoming problem overestimating sulfur‐containing compounds usually encountered ESI. It is characterization highly unsaturated hydrophobic aerosols, such brown carbon‐type with low volatility high stability, which supplementary Conclusions Compared other methods, helps provide complementary description molecular OAs, especially day samples. This may contribute more analysis elusive atmosphere.

Language: Английский

Toxicity of airborne nanoparticles: Facts and challenges DOI Creative Commons
José Portugal, Carmen Bedia, Fúlvio Amato

et al.

Environment International, Journal Year: 2024, Volume and Issue: 190, P. 108889 - 108889

Published: July 18, 2024

Air pollution is one of the most severe environmental health hazards, and airborne nanoparticles (diameter <100 nm) are considered particularly hazardous to human health. They produced by various sources such as internal combustion engines, wood biomass burning, fuel natural gas combustion, their origin, among other parameters, determines intrinsic toxicity for reasons that not yet fully understood. Many constituents toxic or at least hazardous, including polycyclic aromatic hydrocarbons (PAHs) heavy metal compounds, in addition gaseous pollutants present aerosol fraction, NOx, SO2, ozone. All these compounds can cause oxidative stress, mitochondrial damage, inflammation lungs tissues, cellular organelles. Epidemiological investigations concluded may affect respiratory, cardiovascular, nervous systems. Moreover, particulate matter has been linked an increased risk lung cancer, a carcinogenic effect related DNA but inflammatory response pollutants, which release cytokines promotes proliferation pre-existing mutated cancer cells. The mechanisms behind be investigated experimentally using cell cultures animal models. Methods gathering have explored, standardized protocols needed ensure samples accurately represent chemical mixtures environment. Toxic studied models, designing realistic exposure settings challenging. air–liquid interface (ALI) system directly exposes cells, mimicking particle inhalation into lungs. Continuous research monitoring essential understanding effects developing active strategies mitigate risks

Language: Английский

Citations

23
Variation of PM2.5 Redox Potential and Toxicity During Monsoon in Delhi, India DOI Creative Commons
Chunlin Li, Haseeb Hakkim, Vinayak Sinha

et al.

ACS ES&T Air, Journal Year: 2024, Volume and Issue: 1(4), P. 316 - 329

Published: Feb. 22, 2024

This study investigates daily variations in redox potential of water- and organic-soluble PM2.5 during Delhi's monsoon season, offering insights into its chemical composition, cytotoxicity, oxidative threat to various lung conditions. samples, categorized by pollution levels, showed an average intrinsic (OPmDTT) 27.5 pmol min–1 μg–1, OH• generation 51.1 antioxidant capacity (AOC) both gallic acid trolox equivalency 62.5 35.3 respectively. Water-soluble redox-active compounds (RACs) contributed approximately 67% the potential. The polar-phase distribution RACs can be modified atmospheric photochemistry precipitation. Biomass burning emerged as a pivotal source, with polluted samples exhibiting higher cytotoxicity stress A549 cells. All impaired cellular respiration, reducing oxygen consumption rates Intrinsic OPmDTT were influenced fluid variants, such exogenous nicotine endogenous inflammatory protein. provides comprehensive perspective on toxicity Delhi, India distinct periods also points out importance considering population disparities individual health status assessing impacts.

Language: Английский

Citations

4
Diurnal variations of biogenic volatile organic compounds and their role in secondary pollutant formation in the Huai Hong Khrai subtropical forest, Thailand DOI
Sarunpron Khruengsai,

Kan-Amon Phalangrit,

Teerapong Sripahco

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: 372, P. 126044 - 126044

Published: March 11, 2025

Language: Английский

Citations

0
Exposure to Endotoxin Oxidized by Atmospheric Ozone Greatly Enhances Anemia DOI
Huaying Liu,

Qisong Xing,

Chenyu Zhu

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

Endotoxin (lipopolysaccharide, LPS), widely distributed in the atmospheric environment with strong immunogenicity, is an important biological component of ambient particulate matter. However, whether LPS participates chemistry and how its health impacts change relevant processes are poorly understood. In this study, we employed rat model to investigate impact ozone oxidation on toxicity used Fourier transform infrared spectroscopy high-resolution electrospray mass spectrometry study underlying reaction mechanisms. The results show that can be oxidized by resulting reactant greatly enhanced inflammatory anemia a 177% capacity increase despite minor influence immunogenicity. contrast control, rats exposed were observed release characteristic exhaled biomarkers, indicating formed indeed altered effects LPS. Mechanistic investigation reveals hydroxyl group key toxic part LPS, kdo2-lipid A, cause dysregulation iron homeostasis rats, which mechanism LPS-enhanced anemia. Unfortunately, these chemical structure changes cannot detected conventional analysis method. This highlights when need broadly consider involvement bioaerosol chemistry.

Language: Английский

Citations

0
Key Toxicity Enhancement Effect of Aqueous-Phase Secondary Formation: Insights from Hourly Measurements during Haze Events DOI

Feiyan Cao,

Yingjun Chen,

Yong Han

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 138139 - 138139

Published: April 1, 2025

Language: Английский

Citations

0
Sources of organic gases and aerosol particles and their roles in nighttime particle growth at a rural forested site in southwest Germany DOI Creative Commons
Junwei Song, Harald Saathoff, Feng Jiang

et al.

Atmospheric chemistry and physics, Journal Year: 2024, Volume and Issue: 24(11), P. 6699 - 6717

Published: June 10, 2024

Abstract. The composition, sources and chemical transformation of volatile organic compounds (VOCs) aerosol (OA) particles were investigated during July–August 2021 at a rural forested site in southwest Germany, 10 km north the city Karlsruhe. VOCs semi-volatile OA measured with proton-transfer-reaction mass spectrometer coupled to CHemical Analysis aeRosols ONline particle inlet (CHARON–PTR-MS). CHARON-measured accounted for 62 ± 18 % on average total (4.2 2.8 µg m−3) concurrently an (AMS). concentrations ranged from 7.6 88.9 ppb 31.2 13.4 ppb. Positive matrix factorization (PMF) was used identify major source factors particles. Three types oxygenated VOC (OVOC), namely aromatic OVOCs, biogenic OVOCs aged contributed 11 9 %, 37 29 21 concentrations, respectively. results AMS–PMF indicated substantial contributions mass. secondary (SOA) determined by CHARON–PMF analysis, SOA (5 7 %), daytime (17 17 %) nighttime (28 consistently showed high Nighttime growth observed regularly this area, which mainly attributed nitrates formed oxidation monoterpenes sesquiterpenes. This study presents sources, real-time transformations particles, formation characteristics central European areas.

Language: Английский

Citations

2
The chemical composition of secondary organic aerosols regulates transcriptomic and metabolomic signaling in an epithelial-endothelial in vitro coculture DOI Creative Commons
Svenja Offer, Sebastiano Di Bucchianico, Hendryk Czech

et al.

Particle and Fibre Toxicology, Journal Year: 2024, Volume and Issue: 21(1)

Published: Sept. 19, 2024

Language: Английский

Citations

1
Airborne ultrafine particle concentrations and brain cancer incidence in Canada’s two largest cities DOI Creative Commons
Marshall Lloyd, Toyib Olaniyan,

Arman Ganji

et al.

Environment International, Journal Year: 2024, Volume and Issue: unknown, P. 109088 - 109088

Published: Oct. 1, 2024

Language: Английский

Citations

1
Aqueous phase photolysis of 4-nitrocatechol: Reaction kinetics, evolutions of chemical composition, light absorption and oxidation potential DOI

Ruoyuan Lei,

Sha Yu,

Haifeng Meng

et al.

Atmospheric Environment, Journal Year: 2024, Volume and Issue: unknown, P. 120981 - 120981

Published: Dec. 1, 2024

Language: Английский

Citations

1
Sources of organic gases and aerosol particles and their roles in nighttime particle growth at a rural forested site in southwest Germany DOI Creative Commons
Junwei Song, Harald Saathoff, Feng Jiang

et al.

Published: Nov. 29, 2023

Abstract. The composition, sources and chemical transformation of volatile organic compounds (VOCs) aerosol (OA) particles were investigated during July–August 2021 at a rural forested site in southwest Germany. VOCs semi-volatile OA measured with proton-transfer-reaction mass spectrometer coupled particle inlet (CHARON-PTR-MS). CHARON-measured accounted on average for 63 ± 18 % the total (4.2 2.8 μg m-3) concurrently by an (AMS). concentrations ranged from 7.6 to 88.9 ppb 31.2 13.4 ppb. Positive matrix factorization (PMF) was used identify major source factors OA. Three oxygenated VOC (OVOC), namely aromatic-OVOCs, biogenic-OVOCs aged-OVOCs contributed 11 9 %, 37 29 21 concentrations, respectively. results AMS-PMF indicated substantial contributions mass. Consistently, three secondary (SOA) determined CHARON-PMF analysis, aromatic-SOA (5 7 %), daytime-biogenic SOA (17 17 nighttime-biogenic (28 showed high Nighttime growth observed regularly this area, which mainly attributed nitrates formed oxidation monoterpenes sesquiterpenes. This study presents sources, real-time transformations OA, nighttime formation characteristic central European areas.

Language: Английский

Citations

2