Gestational Exposure to Black Phosphorus Nanoparticles Induces Placental Trophoblast Dysfunction by Triggering Reactive Oxygen Species-Regulated Mitophagy DOI
Changqing Zhang, Xiao Li,

Zhenya Fang

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

As a type of two-dimensional nanomaterial, black phosphorus (BP) has attracted considerable interest for applications in various fields. Despite its advantages, including biodegradability and biocompatibility, recent studies have shown that BP exhibits cytotoxicity different types cells. However, no investigated the effects exposure during pregnancy. Herein, we first effect gestational to nanoparticles (BPNPs) mouse model. Our findings indicated BPNPs restricted fetal growth hindered placental development. In HTR8/SVneo trophoblast cells, inhibited cell proliferation, migration, invasion caused apoptosis dose-dependent manner. Furthermore, induced intracellular reactive oxygen species (ROS) overproduction extensive mitochondrial damage. We further demonstrated promoted mitophagy via PINK1/Parkin signaling pathway. Parkin siRNA knockdown rescued BPNPs-induced dysfunction, while ROS inhibition attenuated by reducing Finally, treatment with mdivi-1, inhibitor, mitigated membrane potential reduction, excessive mtROS production, resulting dysfunction. vivo model investigation application mdivi-1 ameliorated embryonic resorption alleviating summary, impairs inducing dysfunction through ROS-regulated, PINK1/Parkin-dependent mitophagy.

Language: Английский

Interfacial engineered biomass-derived G/VMT-PCNCs networks as high-performance proton-conducting humidity sensors DOI
Lirong Tang, Jim‐Wei Wu,

Zhiyi Cao

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 356, P. 123404 - 123404

Published: Feb. 14, 2025

Language: Английский

Citations

0
Flexible and Wearable Electrochemical Sensors for Health and Safety Monitoring DOI
Dan Tao,

Chun Xie,

Nicole Jaffrézic‐Renault

et al.

Talanta, Journal Year: 2025, Volume and Issue: 291, P. 127863 - 127863

Published: March 1, 2025

Language: Английский

Citations

0
Self-adhesive Crystal-enhanced multilayer nanofilm piezoelectric sensor for motion monitoring DOI
KeWei Song, Ze Zhang,

Kayo Hirose

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161150 - 161150

Published: March 1, 2025

Language: Английский

Citations

0
Harnessing the Versatility and Precision of Room-Temperature Multiferroics for Dual-Mode Nanocomposite Hydrogel Biosensor DOI

Rabi Ibrahim Saleh,

Ji Hun Park, Cholong Choi

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Integration of Bio-Enzyme-Treated Super-Wood and AIE-Based Nonwoven Fabric for Efficient Evaporating the Wastewater with High Concentration of Ammonia Nitrogen DOI Creative Commons
Qian Ding,

Bingqi Jin,

Yong‐Fei Zheng

et al.

Nano-Micro Letters, Journal Year: 2025, Volume and Issue: 17(1)

Published: March 10, 2025

Abstract The treatment of ammonia nitrogen wastewater (ANW) has garnered significant attention due to the ecology, and even biology is under increasing threat from over discharge ANW. Conventional ANW methods often encounter challenges such as complex processes, high costs secondary pollution. Considerable progress been made in employing solar-induced evaporators for treatment. However, there remain notable barriers transitioning fundamental research practical applications, including insufficient evaporation rates inadequate resistance biofouling. Herein, we propose a novel evaporator, which comprises bio-enzyme-treated wood aerogel that serves water pumping storage layer, cost-effective multi-walled carbon nanotubes coated hydrophobic/hydrophilic fibrous nonwoven mat functioning photothermal aggregation-induced emission (AIE) molecules incorporated anti-biofouling agent. resultant bioinspired evaporator demonstrates rate 12.83 kg m −2 h −1 when treating simulated containing 30 wt% NH 4 Cl 1.0 sun illumination. AIE-doped exhibits remarkable photodynamic antibacterial activity against mildew bacteria, ensuring outstanding biofouling extended periods When enhanced by natural wind irradiation, achieves an impressive exceeding 20 . This advancement represents promising viable approach effective removal wastewater.

Language: Английский

Citations

0
Metamaterial-Integrated Wearable UWB Antenna with SAR Reduction and Gain Enhancement for Wireless Body Area Sensor Networks (WBASNs): Design and Experimental Verification DOI
Saïd Douhi,

Yassir Houssaini,

Sudipta Das

et al.

Sensors and Actuators A Physical, Journal Year: 2025, Volume and Issue: unknown, P. 116499 - 116499

Published: March 1, 2025

Language: Английский

Citations

0
Biomass Cellulose-Derived Carbon Aerogel Supported Magnetite-Copper Bimetallic Heterogeneous Fenton-like Catalyst Towards the Boosting Redox Cycle of ≡Fe(III)/≡Fe(II) DOI Creative Commons
Qiang Zhao,

Jiawei Yang,

Jiayi Xia

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(8), P. 614 - 614

Published: April 16, 2025

To degrade high-concentration and toxic organic effluents, we developed Fe-Cu active sites loaded on biomass-source carbon aerogel (CA) to produce a low-cost high-efficiency magnetic Fenton-like catalyst for the catalytic oxidative decomposition of pollutants. It exhibits excellent performance in reactions RhB removal at an ultrahigh initial concentration up 1000 ppm. be specific, Fe3O4 Cu nanoparticles are generated situ mesoporous CA support, denoted as Fe3O4-Cu/CA catalyst. Experimentally, factors including dye concentration, dosage, H2O2 pH, temperature, which significantly influence degradation rate RhB, carefully studied. The (1000 ppm) ratio reaches 93.7% within 60 min under low dosage. also shows slight metal leaching (almost 1.4% total Fe 4.0% leached after complete 25 μmol conditions 15 mg 20 mL solution (600 ppm), 200 μL 30 wt% pH 2.5, 40 °C), good activity degrading pollutants, reusability, stability (the is nearly 82.95% 8th cycle reaction). synergistic effect between species plays vital role promoting redox Fe(III)/Fe(II) enhancing generation ·OH. suitable ultrahigh-concentration pollutant practical wastewater treatment applications.

Language: Английский

Citations

0
Harnessing the versatility and precision of room-temperature multiferroics for dual-mode nanocomposite hydrogel biosensor DOI

Rabi Ibrahim Saleh,

Ji Hun Park, Cholong Choi

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162896 - 162896

Published: April 1, 2025

Language: Английский

Citations

0
Gestational Exposure to Black Phosphorus Nanoparticles Induces Placental Trophoblast Dysfunction by Triggering Reactive Oxygen Species-Regulated Mitophagy DOI
Changqing Zhang, Xiao Li,

Zhenya Fang

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

As a type of two-dimensional nanomaterial, black phosphorus (BP) has attracted considerable interest for applications in various fields. Despite its advantages, including biodegradability and biocompatibility, recent studies have shown that BP exhibits cytotoxicity different types cells. However, no investigated the effects exposure during pregnancy. Herein, we first effect gestational to nanoparticles (BPNPs) mouse model. Our findings indicated BPNPs restricted fetal growth hindered placental development. In HTR8/SVneo trophoblast cells, inhibited cell proliferation, migration, invasion caused apoptosis dose-dependent manner. Furthermore, induced intracellular reactive oxygen species (ROS) overproduction extensive mitochondrial damage. We further demonstrated promoted mitophagy via PINK1/Parkin signaling pathway. Parkin siRNA knockdown rescued BPNPs-induced dysfunction, while ROS inhibition attenuated by reducing Finally, treatment with mdivi-1, inhibitor, mitigated membrane potential reduction, excessive mtROS production, resulting dysfunction. vivo model investigation application mdivi-1 ameliorated embryonic resorption alleviating summary, impairs inducing dysfunction through ROS-regulated, PINK1/Parkin-dependent mitophagy.

Language: Английский

Citations

0