Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review
Zeitschrift für Naturforschung C,
Journal Year:
2024,
Volume and Issue:
79(5-6), P. 107 - 124
Published: May 1, 2024
Chitosan
(CT),
a
natural,
cationic,
chemically
stable
molecule,
biocompatible,
biodegradable,
nontoxic,
polysaccharide
derived
from
the
deacetylation
of
chitin,
has
very
uniquely
surfaced
as
material
promise
for
drug
delivery
and
biomedical
applications.
For
oral,
ocular,
cutaneous,
pulmonary,
nose-to-brain
routes,
CT-coated
nanoparticles
(CTCNPs)
have
numerous
advantages,
consisting
improved
controlled
release,
physicochemical
stability,
cell
tissue
interactions,
increased
bioavailability
efficacy
active
ingredient.
CTCNPs
broad
range
therapeutic
properties
including
anticancer,
antiviral,
antifungal,
anti-inflammatory,
antibacterial
properties,
treating
neurological
disorders,
other
diseases.
This
led
to
substantial
research
into
many
potential
uses
CT
vehicle.
also
been
employed
in
wide
processes,
bone
cartilage
regeneration,
ocular
periodontal
heart
wound
healing.
Additionally,
used
cosmeceutical,
bioimaging,
immunization,
gene
transfer
exhibits
number
biological
activities,
which
are
basis
its
remarkable
use
vehicle,
these
activities
covered
detail
this
article.
The
alterations
applied
obtain
necessary
described.
Language: Английский
Revolutionizing Neurological Therapies: The Role of 3D-Printed Microneedles in Precision Brain-Targeted Drug Delivery
Journal of Drug Delivery Science and Technology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106818 - 106818
Published: March 1, 2025
Language: Английский
Nanoparticle-Based Biomarkers for Neurological Disorders
Neelakanta Sarvashiva Kiran,
No information about this author
Chandrashekar Yashaswini,
No information about this author
Ankita Chatterjee
No information about this author
et al.
Nanotechnology in the life sciences,
Journal Year:
2025,
Volume and Issue:
unknown, P. 183 - 202
Published: Jan. 1, 2025
Language: Английский
Phyto-mediated polymeric incorporated silver nano-bio-composite for improved dermal complication management: A review
Min He,
No information about this author
Jun Hu,
No information about this author
J. S. Deng
No information about this author
et al.
Results in Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 102272 - 102272
Published: April 1, 2025
Language: Английский
Demystifying the Role of Neuroinflammatory Mediators as Biomarkers for Diagnosis, Prognosis, and Treatment of Alzheimer’s Disease: A Review
ACS Pharmacology & Translational Science,
Journal Year:
2024,
Volume and Issue:
7(10), P. 2987 - 3003
Published: Sept. 26, 2024
Neuroinflammatory
mediators
play
a
pivotal
role
in
the
pathogenesis
of
Alzheimer's
Disease
(AD),
influencing
its
onset,
progression,
and
severity.
The
precise
mechanisms
behind
AD
are
still
not
fully
understood,
leading
current
treatments
to
focus
mainly
on
managing
symptoms
rather
than
preventing
or
curing
condition.
amyloid
tau
hypotheses
most
widely
accepted
explanations
for
pathology;
however,
they
do
completely
account
neuronal
degeneration
observed
AD.
Growing
evidence
underscores
crucial
neuroinflammation
pathology
neuroinflammatory
hypothesis
presents
promising
new
approach
understanding
driving
This
review
examines
importance
biomarkers
diagnosis,
prognosis,
treatment
It
delves
into
underlying
AD,
highlighting
involvement
various
such
as
cytokines,
chemokines,
ROS.
Additionally,
this
discusses
potential
diagnostic
tools,
prognostic
indicators,
therapeutic
targets
management.
By
intricate
interplay
between
pathology,
aims
help
development
efficient
plans
fight
debilitating
neurological
Furthermore,
it
elaborates
recent
advancements
neuroimaging
techniques
biofluid
analysis
identification
monitoring
patients.
Language: Английский
Nanocrystals: a new herald for the management of Alzheimer’s disease
Journal of Dispersion Science and Technology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 14
Published: Oct. 6, 2024
Alzheimer's
disease
(AD)
impairs
mental
development
and
interrupts
neurocognitive
functions
that
escalate
with
time
leading
to
death.
With
continuous
evolution
in
lifestyle
progression
of
age,
the
prevalence
AD
is
progressively
rising,
a
significant
economic
burden.
Thus,
effective
therapeutic
approaches
are
indeed
necessary
address
this
growing
concern.
Current
treatment
regimens
primarily
help
relieve
symptoms,
nevertheless,
nanotechnology-based
nerve
damage
can
be
regressed
along
reduction
inflammation
improved
brain
delivery.
Researchers
healthcare
professionals
working
diligently
develop
innovative
treatments
interventions
improve
quality
life
for
individuals
affected
by
AD.
This
review
paper
aims
provide
comprehensive
insights
on
pathogenesis,
FDA-approved
treatment,
recent
advancements
drug
therapy,
formulation
an
update
drugs
different
clinical
phases.
The
specifically
highlights
nanocrystals-based
formulations
their
ability
minimize
side
effects,
bioavailability,
pharmacodynamics
pharmacokinetics.
current
also
prospects
role
NCs
enabling
delivery
across
BBB
it
dives
deep
understand
its
potential
carve
out
directions
niche
area
treating
Language: Английский