METTL14-mediated lncRNA NEAT1 promotes asthma progression by regulating the miR-302a-3p/March5 axis DOI
Yifei Wu, Qing Ye, Dandan Chen

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 158, P. 114850 - 114850

Published: May 12, 2025

Language: Английский

Therapeutic applications and potential biological barriers of nano-delivery systems in common gastrointestinal disorders: a comprehensive review DOI Creative Commons
Guoliang Zheng, Bao Zhang, Hou‐Yong Yu

et al.

Advanced Composites and Hybrid Materials, Journal Year: 2025, Volume and Issue: 8(2)

Published: April 1, 2025

Language: Английский

Citations

3
Microencapsulation of Deer Oil in Soy Protein Isolate–Chitosan Complex Coacervate—Preparation, Characterization, and Simulated Digestion DOI Creative Commons
Hongyan Li, Ying Zong, Weijia Chen

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(2), P. 181 - 181

Published: Jan. 9, 2025

Deer oil (DO) is a potentially beneficial functional oil; however, its sensitivity to environmental factors (e.g., oxygen and heat), difficulty in transport, unfavorable taste hinder practical use. In this study, DO was encapsulated through the cohesive action of soy protein isolate (SPI) chitosan (CS). The optimal preparation conditions yielded microcapsules with DO's highest encapsulation efficiency (EE) (85.28 ± 1.308%) at an SPI/CS mixing ratio 6:1 core-to-wall 1:2 pH 6. Fluorescence scanning electron microscopy were utilized examine microcapsules' structure, showing intact surfaces effective droplets composite coalescence. Through Fourier transform infrared spectroscopy (FTIR), electrostatic interplay between SPI CS verified during merging process. At room temperature, resisted core oxidation by reducing gas permeation. vitro simulated digestion results indicated achieved slow sustained release intestinal tract. This study further expands application scope deer promotes development preparations foods.

Language: Английский

Citations

0
Qiangji Decoction mitigates neuronal damage, synaptic and mitochondrial dysfunction in SAMP8 mice through the regulation of ROCK2/Drp1-mediated mitochondrial dynamics DOI

Bixuan Lai,

Dan Wu, Qiang Xiao

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119424 - 119424

Published: Jan. 1, 2025

Language: Английский

Citations

0
Longan Aril polysaccharides ameliorate cognitive impairment in AD mice via restoration of the immune phagocytosis of microglia DOI
Han Zhang,

F.H. Tra Bi,

Peng Zhao

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: 343, P. 119464 - 119464

Published: Feb. 8, 2025

Language: Английский

Citations

0
Cranberry Extract Ameliorates Diabetic Cognitive Impairment in Rats Via LncRNA GAS-5 Downregulation and Pyroptosis Pathway Inhibition DOI Creative Commons
Mariam A. Abo-Saif, Amany E. Ragab, Iman M. Talaat

et al.

Journal of Neuroimmune Pharmacology, Journal Year: 2025, Volume and Issue: 20(1)

Published: April 21, 2025

Abstract The pathophysiology of diabetes-induced brain injury involves pyroptosis, an inflammatory programmed cell death. This study aimed to investigate the potential protective effect cranberry extract (CE) against injury. Type 1 diabetes was induced by intraperitoneal injection streptozotocin in rats. Brain tissue samples were investigated for biochemical determination reduced glutathione (GSH), superoxide dismutase (SOD), and malondialdehyde (MDA), quantitative RT-PCR gene expression glial cell-derived neurotrophic factor (GDNF), lncRNA GAS-5, pyroptosis markers. ELISA used determine caspase-1 level immunohistochemical staining assessing IL-1β. Prophylactic dosing CE diabetic rats improved cognitive behavior significantly suppressed MDA concentration, genes (gasdermin D caspase 1), GAS-5. In addition, elevated GSH SOD activity, GDNF markedly IL-1β positive stained cells score brain. Phytochemical characterization FT-IR UPLC-PDA-MS/MS revealed cyanidin arabinoside, procyanidins, quercetin, isorhamnetin as key components. protects dysfunction targeting redox-related signaling pathways inducing anti-inflammatory effect. LncRNA GAS-5 downregulation pathway inhibition may contribute its beneficial effects, suggesting therapeutic potential.

Language: Английский

Citations

0
Physicochemical characterization and evaluation of the antioxidant potential of water-soluble polysaccharides from red microalgae, Rhodomonas salina DOI Creative Commons

Farjana Akter,

Lakshmi Krishnan, Gemma Mestres

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143417 - 143417

Published: April 1, 2025

Language: Английский

Citations

0
NOD-like receptor protein 3 inhibitors in St. John's wort and their potential antidepressant effects DOI

Xue-Ge Pan,

Weifeng Yin,

Man-Ni Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 306, P. 141721 - 141721

Published: March 3, 2025

Language: Английский

Citations

0
Immunomodulatory effects of Sanghuangporus flavonoids: Key insights into enhancing immunity and restoring immune function DOI

Xue Liu,

Zhinan Li,

Hongqing Xie

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 153, P. 114474 - 114474

Published: March 21, 2025

Language: Английский

Citations

0
Structure changes of starch complexed with green tea catechin or lemon peel caffeic acid under thermomechanical-assist low moisture and their prebiotics during in vitro digestion and fermentation DOI
Hai He,

Fanrui Liu,

Lei Yang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142676 - 142676

Published: March 1, 2025

Language: Английский

Citations

0
Immune Restoration Mechanism Analysis of Akkermansia PROBIO in Mice Treated with Cyclophosphamide through Re-balancing Microbiota Composition DOI
Junpeng Zhang, Xin Ma, Wenjiao Du

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106450 - 106450

Published: March 1, 2025

Language: Английский

Citations

0