
International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 6059 - 6083
Published: May 1, 2025
Breast cancer remains the leading cause of female mortality worldwide, necessitating innovative and multifaceted approaches to address its various subtypes. Nanotechnology has attracted considerable attention due nanoscale dimensions, diverse carrier types, suitability for hydrophobic drug delivery, capacity controlled targeted administration. Nano-sized particles have become prevalent carriers therapeutic agents targeting breast cancer, thanks their reproducible synthesis adjustable properties, including size, shape, surface characteristics. In addition, certain nanoparticles can enhance effects synergistically. However, immune system often detects removes these nanoparticles, limiting efficacy. As a promising alternative, cell membrane-based delivery systems gained biocompatibility specificity. These membrane-coated are derived from sources, blood cells, stem cells. Leveraging unique properties membranes enables precise tumors associated biomarkers. Inspired by natural structures, disguise in bloodstream, enhancing retention time vivo improving tumor targeting. Consequently, membrane-derived (CMDNPs) been investigated potential applications diagnostics, photothermal therapy (PTT), vaccine development. This review comprehensively explores limitations clinical against cancer.
Language: Английский