Hybrid 3D Bioprinting of Sustainable Biomaterials for Advanced Multiscale Tissue Engineering
Xuejiao Ma,
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Mingqi Xu,
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Xiaolin Cui
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et al.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 27, 2025
Abstract
3D
printing
has
greatly
improved
the
precision
of
cell
and
biomaterial
placement,
enabling
accurate
reproduction
tissue
models
with
sustainable
potential.
Various
techniques,
including
inkjet
printing,
extrusion‐based
vat
photopolymerization,
offer
unique
advantages
but
often
fail
to
replicate
full
complexity
native
tissues
because
material
scalability
limitations.
Hybrid
bioprinting,
combining
multiple
techniques
in
a
single
process,
shown
great
potential
creating
complex
multifunctional
capabilities,
ranging
from
patient‐specific
implant
fabrication
full‐scale
organ
development.
It
capitalizes
on
strengths
integration
sustainable,
renewable
biomaterials
at
varying
resolutions,
nano
microscale.
This
approach
addresses
both
biological
environmental
responsibility
by
minimizing
waste
enhancing
sustainability
engineering
processes.
Despite
progress,
substantial
gap
remains
between
current
technologies
bioengineering
requirements.
A
deep
understanding
hybrid
its
underlying
mechanisms
is
crucial.
Herein,
this
review
summarizes
discusses
recent
advancements
systems
for
fabricating
multiscale
hierarchical
models,
focusing
challenges
field.
aims
insights
identify
key
requirements
advancing
technology
toward
developing
functional,
biomimetic
constructs.
Language: Английский
BDM editors pick the most memorable moments of 2024
Bio-Design and Manufacturing,
Journal Year:
2025,
Volume and Issue:
8(1), P. 166 - 168
Published: Jan. 1, 2025
Language: Английский
Biomaterials and emerging technologies for tissue engineering and in vitro models
Bio-Design and Manufacturing,
Journal Year:
2024,
Volume and Issue:
7(3), P. 237 - 239
Published: May 1, 2024
The
latest
advances
in
the
field
of
biomaterials
have
opened
new
avenues
for
scientific
breakthroughs
tissue
engineering
which
greatly
contributed
successful
translation
products
into
market/clinics.Biomaterials
are
easily
processed
to
become
similar
natural
extracellular
matrix,
making
them
ideal
temporary
supports
mimicking
three-dimensional
(3D)
microenvironment
required
maintaining
adequate
cell/tissue
functions
both
vitro
and
vivo
[1].The
integration
functionalized
with
emerging
technologies
such
as
microfluidics
3D
printing
brings
a
myriad
advantages
manufacturing
complex
designs
broad
applications
regenerative
medicine,
tissue/disease
models
(Fig.
1).The
special
issue
gathers
two
excellent
reviews
five
original
works
dealing
design
functionalization
biomaterials,
advanced
manufacturing,
models.The
recent
progresses
Israel
summarized.Moreover,
developments
related
biodesign
strategies
(nano)
particular
hydrogels/bioinks
semicrystalline
polymers
enhancing
controlling
cell
functions,
also
provided.An
overview
cellular
interplay
microphysiological
disease
focus
on
microbiota-gut-brain
axis
is
presented.Finally,
Language: Английский
Biofabrication and biomanufacturing in Ireland and the UK
Bio-Design and Manufacturing,
Journal Year:
2024,
Volume and Issue:
7(6), P. 825 - 856
Published: Oct. 23, 2024
摘要
随着我们从第四次工业革命向第五次工业革命的过渡，生物制造领域的兴起正在改变生命科学和医疗保健。3D生物打印、组织工程、定向组装和自组装等先进技术在创建仿生支架、组织类器官、医疗设备和生物系统方面发挥着重要作用。英国和爱尔兰的生物制造领域成为生物科学和医疗保健的关键力量，得益于尖端的研究和发展。这些地区的研究专注于药物输送、体外模型,
类器官,和组织工程的生物功能产品，致力于创新符合伦理标准的医疗保健解决方案，同时支持环保和有效的医疗保健系统。