Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes DOI Creative Commons

Andrej Vikartovský,

Natália Košútová, Lenka Lorencová

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Herein, the basic properties, composition, and isolation methods for separation of exosomes are described, since they can be a rich source disease biomarkers. Then an introduction to MXenes, novel class 2D nanomaterials with interesting properties applicable in numerous fields including biosensing is provided. Also, aptamers described as alternative antibodies robust biorecognition analytes interest. The final part article gives examples which these three key components integrated sensitive and/or electrochemical detection exosomes. conclusion provides summary initial achievements also outlook future discoveries exosome aptasensing using advanced nanomaterials, i.e., MXenes. MXenes have promising affinity‐based biosensing, being hydrophilic surface functional groups. In addition, free plasmons present used covalent grafting elements diazonium moieties. This especially approach immobilization DNA/RNA aptamers, readily modified by

Language: Английский

Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes DOI Creative Commons

Andrej Vikartovský,

Natália Košútová, Lenka Lorencová

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Herein, the basic properties, composition, and isolation methods for separation of exosomes are described, since they can be a rich source disease biomarkers. Then an introduction to MXenes, novel class 2D nanomaterials with interesting properties applicable in numerous fields including biosensing is provided. Also, aptamers described as alternative antibodies robust biorecognition analytes interest. The final part article gives examples which these three key components integrated sensitive and/or electrochemical detection exosomes. conclusion provides summary initial achievements also outlook future discoveries exosome aptasensing using advanced nanomaterials, i.e., MXenes. MXenes have promising affinity‐based biosensing, being hydrophilic surface functional groups. In addition, free plasmons present used covalent grafting elements diazonium moieties. This especially approach immobilization DNA/RNA aptamers, readily modified by

Language: Английский

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