International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(9), P. 4858 - 4858
Published: April 29, 2024
Melatonin
and
sericin
exhibit
antioxidant
properties
may
be
useful
in
topical
wound
healing
patches
by
maintaining
redox
balance,
cell
integrity,
regulating
the
inflammatory
response.
In
human
skin,
melatonin
suppresses
damage
caused
ultraviolet
radiation
(UVR)
which
involves
numerous
mechanisms
associated
with
reactive
oxygen
species/reactive
nitrogen
species
(ROS/RNS)
generation
enhancing
apoptosis.
Sericin
is
a
protein
mainly
composed
of
glycine,
serine,
aspartic
acid,
threonine
amino
acids
removed
from
silkworm
cocoon
(particularly
Bombyx
mori
other
species).
It
interest
because
its
biodegradability,
anti-oxidative,
anti-bacterial
properties.
inhibits
tyrosinase
activity
promotes
proliferation
that
can
supportive
melanoma
treatment.
recent
years,
containing
individually
have
attracted
significant
attention
scientific
community.
this
review,
we
summarize
state
innovation
such
during
2021–2023.
To
date,
melatonin/sericin-polymer
for
application
post-operational
treatment
has
been
only
sparingly
investigated
it
an
imperative
to
consider
these
materials
as
promising
approach
targeting
skin
tissue
engineering
or
regenerative
dermatology.
Journal of Biomedical Materials Research Part B Applied Biomaterials,
Journal Year:
2024,
Volume and Issue:
112(1)
Published: Jan. 1, 2024
Abstract
Hyaluronic
acid
(HA)
and
chitosan
(CS),
as
natural
biomaterials,
display
excellent
biocompatibility
stimulate
the
growth
proliferation
of
fibroblasts.
Furthermore,
nylon
6
(N6)
is
a
low‐cost
polymer
with
good
compatibility
human
tissues
high
mechanical
stability.
In
this
study,
HA
CS
were
applied
to
modify
N6
nanofibrous
mat
(N6/HA/CS)
for
potential
wound
dressing.
N6/HA/CS
composite
mats
developed
using
simple
one‐step
electrospinning
technique
at
different
concentrations
1,
2,
3
wt%.
The
results
demonstrated
that
incorporating
into
resulted
in
increased
hydrophilicity,
well
favorable
physical
properties.
addition,
minimum
inhibitory
concentration
(MIC)
optical
density
techniques
used
determine
antibacterial
properties
mats,
composites
could
markedly
inhibit
Gram‐positive
bacteria
Staphylococcus
aureus
Gram‐negative
Escherichia
coli
.
Because
its
superior
properties,
substantial
antimicrobial
effects,
hydrophilic
surface,
2
wt%
(N6/HA/CS2)
was
chosen
most
suitable
mat.
swelling,
porosity,
gel
content,
vitro
degradation
studies
imply
N6/HA/CS2
has
proper
moisture
retention
biodegradability.
discovered
be
nontoxic
L929
fibroblast
cells
even
improve
cell
proliferation.
Based
on
findings,
research
offers
rapid
method
creating
material
utilized
prospective
dressings
clinical
environments.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(8), P. 1852 - 1852
Published: April 12, 2023
Konjac
glucomannan
(KGM)
is
a
naturally
occurring
macromolecular
polysaccharide
that
exhibits
remarkable
film–forming
and
gel–forming
properties,
high
degree
of
biocompatibility
biodegradability.
The
helical
structure
KGM
maintained
by
the
acetyl
group,
which
plays
crucial
role
in
preserving
its
structural
integrity.
Various
degradation
methods,
including
topological
structure,
can
enhance
stability
improve
biological
activity.
Recent
research
has
focused
on
modifying
to
utilizing
multi–scale
simulation,
mechanical
experiments,
biosensor
research.
This
review
presents
comprehensive
overview
properties
KGM,
recent
advancements
non–alkali
thermally
irreversible
gel
research,
applications
biomedical
materials
related
areas
Additionally,
this
outlines
prospects
for
future
providing
valuable
ideas
follow–up
experiments.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(8), P. 10785 - 10794
Published: Feb. 15, 2024
Food
packaging
detection
devices
have
attracted
attention
to
optimize
storage
situations
and
reduce
food
spoilage.
However,
low-cost
highly
sensitive
multifunctional
sensors
for
detecting
both
freshness
pressure
are
still
lacking.
In
this
study,
a
sensor
was
developed
consisting
of
MXene
coated
alcohol-soluble
polyurethane
fiber
network
(MXene/APU)
composite
biohydrogel
films
made
konjac
glucomannan,
chitosan,
blueberry
anthocyanin
(KCB).
Based
on
the
sensitivity
MXene/APU
color
changes
KCB
in
response
pH
values,
can
detect
internal
package
bulging,
external
squeezing,
deterioration.
The
shows
1.16
kPa–1,
time
200
ms,
wide
strain
range
1092%,
stability
over
multiple
loops.
could
human
motion
identify
surface
morphologies.
excellent
performance
attributed
porous
structure
large
specific
area
microfiber
networks,
conductivity
nanosheets,
protective
effect
conductive
membrane.
Besides,
microfluidic
blow-spinning
method
used
prepare
networks
showed
advantages
low
energy
consumption
high
production
efficiency.
loaded
pH,
realized
spoilage
containing
protein.
This
study
provides
new
sensing
device
greater
understanding
optimization
application
related
devices.
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 10, 2025
Abstract
The
development
of
3D‐printable
and
injectable
biocompatible
hydrogels
with
robust
mechanical
adhesive
properties
useful
for
biomedical
applications
remains
a
great
challenge.
Herein,
stepwise‐triggered
dual
reversible/irreversible
covalent
linkages
are
engineered
between
two
functionalized
polymers,
glycidyl
methacrylate‐modified
polyvinyl
alcohol
(PVA‐GMA)
oxidized
sodium
alginate
tailed
3‐aminophenylboronic
acid
(OSA‐PBA),
allowing
the
availability
PVA‐GMA/OSA‐PBA
(PGOP)
versatile
functions.
PGOP
have
excellent
injectability,
processability,
strength
(39.5
±
2.3
kPa),
self‐healing,
elasticity
toughness
(80%
compressive
strain
at
84.5
kPa
stress),
bioadhesion
(34.2
2.7
to
fresh
pig
skin,
vs
7.3–15.38
commercial
fibrin
glue
adhesives),
degradability,
antibacterial
property,
biocompatibility
(265%
cell
survival
fibroblasts
co‐culture
5
d).
With
these
merits,
pregel
can
be
applied
as
3D‐printing
construct
materials
produce
diverse
3D
hierarchical
architectures
high
shape
fidelity,
good
properties,
active
materials‐laden
capacity.
mouse
liver
hemorrhage
model
full‐thickness
skin
defect
demonstrate
that
hemostatic
ability
accelerated
wound
healing
Therefore,
this
work
provides
hydrogel
adhesives
favorable
various
such
tissue
engineering
healing.
