The Antimicrobial Efficacy of Sodium Hypochlorite and Chlorhexidine in Gutta-Percha Cone Decontamination: A Systematic Review DOI Open Access
Ruta Aucinaite, Eglė Nedzinskienė, Vytautė Pečiulienė

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(7), P. 1539 - 1539

Published: March 28, 2025

This systematic review aims to compare the efficacy of sodium hypochlorite (NaOCl) and chlorhexidine digluconate (CHX) in decontaminating gutta-percha (GP) cones against endodontic pathogens—Enterococcus faecalis (E. faecalis), Staphylococcus aureus (S. aureus), Candida albicans (C. albicans)—within 0–10 min. A search was conducted six databases (PubMed, Web Science, Cochrane Library, SCIELO, Scopus, LILACS), supplemented by manual searches performed independently three reviewers. No publication year restrictions were applied, only English-language studies included. followed PRISMA statement (Preferred Reporting Items for Systematic Reviews Meta-Analyses). The risk bias assessed using parameters with a modified tool. Out 309 potentially eligible studies, 216 screened title abstract, 32 selected full-text assessments, 7 All had moderate or high bias. majority included showed that higher NaOCl concentrations effectively eliminate E. S. within 1–5 However, data on CHX’s antimicrobial effect C. limited. qualitative analysis suggests remains most effective agent GP decontamination, while CHX additives shows potential fungal species.

Language: Английский

The Antimicrobial Efficacy of Sodium Hypochlorite and Chlorhexidine in Gutta-Percha Cone Decontamination: A Systematic Review DOI Open Access
Ruta Aucinaite, Eglė Nedzinskienė, Vytautė Pečiulienė

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(7), P. 1539 - 1539

Published: March 28, 2025

This systematic review aims to compare the efficacy of sodium hypochlorite (NaOCl) and chlorhexidine digluconate (CHX) in decontaminating gutta-percha (GP) cones against endodontic pathogens—Enterococcus faecalis (E. faecalis), Staphylococcus aureus (S. aureus), Candida albicans (C. albicans)—within 0–10 min. A search was conducted six databases (PubMed, Web Science, Cochrane Library, SCIELO, Scopus, LILACS), supplemented by manual searches performed independently three reviewers. No publication year restrictions were applied, only English-language studies included. followed PRISMA statement (Preferred Reporting Items for Systematic Reviews Meta-Analyses). The risk bias assessed using parameters with a modified tool. Out 309 potentially eligible studies, 216 screened title abstract, 32 selected full-text assessments, 7 All had moderate or high bias. majority included showed that higher NaOCl concentrations effectively eliminate E. S. within 1–5 However, data on CHX’s antimicrobial effect C. limited. qualitative analysis suggests remains most effective agent GP decontamination, while CHX additives shows potential fungal species.

Language: Английский

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