Gene Therapy for Cystic Fibrosis: Overcoming Current Limitations and Future Directions
Nadir Ali Wassan,
No information about this author
Asfia Qammar,
No information about this author
Sarah Bürki
No information about this author
et al.
Indus journal of bioscience research.,
Journal Year:
2025,
Volume and Issue:
3(3), P. 133 - 145
Published: March 16, 2025
Cystic
fibrosis
(CF)
is
a
lethal
inherited
disorder
resulting
from
mutations
in
the
CFTR
gene
that
cause
improper
chloride
ion
movement
and
clogging
of
lungs
with
mucus.
While
classic
therapies
have
been
augmented
by
modulators
airway
clearance
techniques,
these
remain
limited
expense,
specificity
for
mutation,
need
lifetime
therapy.
Gene
therapy
has
suggested
as
curative
treatment,
wherein
goal
to
repair
defective
through
techniques
such
CRISPR-Cas9,
viral/non-viral
vectors,
stem
cell-based
This
study
employed
mixed-methods
setting,
integrating
survey-based
assessment
meta-analysis
existing
literature
evaluate
awareness,
perception,
barriers
implementation
among
CF
patients
caregivers
Punjab,
Pakistan.
A
questionnaire
was
given
65
participants,
qualitative
data
analysis
SPSS
established
significant
awareness
gap,
where
socioeconomic
status
education
level
were
major
determinants.
Chi-square
ANOVA
tests
statistically
relationships
between
demographic
variables
acceptance.
Moreover,
found
consistent
trends
current
research
indicating
similar
problems
accessibility,
ethical
concerns,
necessity
improved
delivery
systems.
The
results
reaffirm
further
patient
education,
increased
affordability,
more
clinical
verification
make
therapeutic
reality.
In
general,
underscores
promise
while
encouraging
multidisciplinary
methods
overcome
limitations.
examines
perceptions
cystic
Pakistan,
revealing
low
knowledge
levels
influenced
factors.
Challenges
include
cost,
safety
implications.
Future
efforts
must
integrate
research,
policy
reforms,
advocacy
enhance
therapy’s
feasibility
availability.
Language: Английский
EAFL: Edge-Assisted Federated Learning for real-time disease prediction using privacy-preserving AI
Iran Journal of Computer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 20, 2025
Language: Английский
Responsible AI in Indonesian higher education: A survey in sports education and public health programs
Syahruddin Syahruddin,
No information about this author
Muhammad Saleh,
No information about this author
Mailizar Mailizar
No information about this author
et al.
Social Sciences & Humanities Open,
Journal Year:
2025,
Volume and Issue:
11, P. 101445 - 101445
Published: Jan. 1, 2025
Language: Английский
The Future of Higher Education: Trends, Challenges and Opportunities in AI-Driven Lifelong Learning in Peru
Information,
Journal Year:
2025,
Volume and Issue:
16(3), P. 224 - 224
Published: March 14, 2025
This
study
analyses
future
trends
in
lifelong
learning
the
Peruvian
context.
Using
DeflyCompass
model,
an
artificial
intelligence
tool,
main
affecting
evolution
of
postgraduate
studies
were
identified,
including
impact
generative
AI
on
personalisation
education,
transformation
work
and
growth
Generation
Z
as
key
players
educational
environment.
The
methodology
applied
combines
a
mixed
qualitative
quantitative
approach,
based
opinion
experts—45
participants
from
seven
public/private
universities
Peru—the
technique
semantic
projections,
use
generalist
search
engines
specialised
databases,
other
digital
management
resources
such
Google
Scholar
profile
analysis
online
marketing
campaign
design
tools.
In
particular,
total
150
scientific
papers
300
articles
sources
analysed.
approach
made
it
possible
to
select,
analyse
quantify
higher
education
Peru
assess
their
potential
development
graduate
schools,
specifically
case
Pontificia
Universidad
Católica
de
Perú
(PUCP).
results
highlight
importance
adapting
new
demands,
adoption
AI,
adaptation
personalised
integration
technologies
enhance
personal
professional
students.
It
also
highlights
need
incorporate
strategies
that
address
work,
with
focus
developing
skills
preparing
for
ever-changing
thus
provides
guide
how
adapt
programmes
emerging
trends,
promoting
flexible
technologically
advanced
responds
needs
professionals.
Language: Английский
Bridging Business Strategy and Educational Development: Private Sector Engagement and Value Creation Framework for Sustainable E‐Learning Models in Emerging Markets
Rajia Sultana,
No information about this author
Md. Ariful Haque Chowdhury,
No information about this author
TA Chowdhury
No information about this author
et al.
Business Strategy & Development,
Journal Year:
2025,
Volume and Issue:
8(1)
Published: March 1, 2025
ABSTRACT
As
developing
economies
embrace
digital
transformation
to
bridge
educational
gaps,
the
intersection
of
business
strategy
and
development
offers
significant
opportunities.
This
study
explores
how
private
sector
engagement
in
e‐learning
can
drive
growth
achieve
outcomes
Bangladesh's
higher
education
sector.
Through
mixed‐methods
analysis
780
stakeholders
across
institutions,
we
examine
technology
strategies
create
shared
value
while
addressing
accessibility
challenges
markets.
Our
findings
show
that
well‐structured
implementations
simultaneously
commercial
viability
impact.
Six
critical
success
factors
were
identified:
administrative
infrastructure,
technological
architecture,
content
development,
instructor
capabilities,
learner
characteristics,
social
support.
Infrastructure
partnerships
with
balanced
public–private
investment
sharing
achieved
75%
rates,
collaborations
enhanced
learning
by
35%.
The
highlights
three
mechanisms
supporting
Sustainable
Development
Goals:
innovative
models
balancing
impact,
leveraging
corporate
expertise,
inclusive
stakeholder
frameworks.
Theoretically,
extend
theory
demonstrating
complementary
creation
be
optimized
multiple
groups
implementations.
We
contribute
model
innovation
frameworks
identifying
specific
through
which
sustainable
is
created,
delivered,
captured
market
contexts.
These
insights
are
valuable
for
businesses
entering
emerging
markets
policymakers
creating
enabling
environments
initiatives.
Language: Английский