A new era of cancer immunotherapy: vaccines and miRNAs

Cancer Immunology Immunotherapy, Journal Year: 2025, Volume and Issue: 74(5)

Published: April 1, 2025

Language: Английский

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Emerging Targets in Amyotrophic lateral sclerosis (ALS): The Promise of ATP-Binding Cassette (ABC) transporter Modulation

Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 476, P. 115242 - 115242

Published: Sept. 6, 2024

Language: Английский

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Unveiling Acid-Sensing Ion Channels (ASICs) in Neurodegeneration: Implications for Disease Pathogenesis and Therapeutic Strategies

Current Pharmacology Reports, Journal Year: 2025, Volume and Issue: 11(1)

Published: March 11, 2025

Language: Английский

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Revenge Unraveling the Fortress: Exploring Anticancer Drug Resistance Mechanisms in BC for Enhanced Therapeutic Strategies

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104707 - 104707

Published: March 1, 2025

Language: Английский

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Aquaporin proteins: A promising frontier for therapeutic intervention in cerebral ischemic injury

Cellular Signalling, Journal Year: 2024, Volume and Issue: 124, P. 111452 - 111452

Published: Oct. 5, 2024

Language: Английский

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Pharmacological modulation of Sonic Hedgehog signaling pathways in Angiogenesis: A mechanistic perspective

Developmental Biology, Journal Year: 2023, Volume and Issue: 504, P. 58 - 74

Published: Sept. 20, 2023

Language: Английский

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Essential roles of sensory nerve in maintenance of cornea-phenotype in mice

The Ocular Surface, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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The synergistic link between sonic hedgehog signaling pathway and gut–lung axis: Its influential role toward chronic obstructive pulmonary disease progression

Developmental Dynamics, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Abstract Sonic Hedgehog (SHH) is an evolutionarily conserved signaling pathway essential for embryonic development, tissue homeostasis, and tumorigenesis. Aberrant activation of the SHH induces various types cancer different immune dysregulation. extremely important morphogen during lung as it regulates interaction between epithelial mesenchymal transitions (EMT) in airways. Cigarette smoking triggers EMT activates pathway, which leads to damage development diseases, such COPD, a smoker's disease. also directs gut–lung axis (GLA) formation via epithelial–mesenchymal signaling. The abruption or alteration GLA responsible COPD pathogenesis. In this review, we elucidate overview its inhibitor HHIP, SHH's prominence dysregulation pathogenesis link with clinical features. We provide insights into linked nicotine their influence on

Language: Английский

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Unravelling the role of protein kinase R (PKR) in neurodegenerative disease: a review

Molecular Biology Reports, Journal Year: 2025, Volume and Issue: 52(1)

Published: April 9, 2025

Language: Английский

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Unravelling the role of Interleukin-12 in Neuroinflammatory mechanisms: Pathogenic pathways linking Neuroinflammation to neuropsychiatric disorders

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 156, P. 114654 - 114654

Published: April 27, 2025

Language: Английский

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