Effects of 630 nm laser on apoptosis, metastasis, invasion and epithelial-to-mesenchymal transition of human lung squamous cell carcinoma H520 cells mediated by hematoporphyrin derivatives DOI
Tingting Liu,

Enhua Zhang,

Shichao Cui

et al.

Lasers in Medical Science, Journal Year: 2024, Volume and Issue: 39(1)

Published: Aug. 30, 2024

Language: Английский

Photodynamic Therapy in Cancer: Insights into Cellular and Molecular Pathways DOI Creative Commons

Vincenzo Papa,

Fabiana Furci, Paola Lucia Minciullo

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(2), P. 69 - 69

Published: Jan. 21, 2025

Photodynamic therapy is a non-ionizing radiation treatment that utilizes photosensitizer in combination with light to produce singlet oxygen. This oxygen induces anti-cancer effects by causing apoptotic, necrotic, or autophagic cell death tumor cells. Currently, photodynamic employed oncology treat various cancers. In the presence of oxygen, this non-invasive approach leads direct death, damage microvasculature, and induction local inflammatory response. These allow be effective treating early-stage tumors, extending survival cases where surgery not feasible, significantly improving quality life. paper, we provide state art on cytomolecular mechanisms associated pathways involved therapy. By integrating these mechanistic insights most recent advancements nanotechnology, phototherapeutic has potential become prevalent option within conventional cancer therapies, enhancing its application precision medicine.

Language: Английский

Citations

2
Hypericin impedes M2 macrophage polarization and protects against Hepatocellular carcinoma DOI

X. Y. Wen,

Xianling Wang, Qing Yao

et al.

Molecular Immunology, Journal Year: 2025, Volume and Issue: 181, P. 160 - 168

Published: March 29, 2025

Language: Английский

Citations

0
Insight into the Role of the miR-584 family in Human Cancers DOI Open Access
Mariantonia Braile, Neila Luciano,

Davide Carlomagno

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7448 - 7448

Published: July 6, 2024

Among the non-coding RNAs, aberrant expression of microRNAs (miRNAs) is well described in oncology field. It clear that altered miRNAs crucial for a variety processes such as proliferation, apoptosis, motility, angiogenesis and metastasis insurgence. Considering these aspects, RNA-based therapies use non-invasive biomarkers early diagnosis are underlined promising opportunities against cancer death. In era precision medicine, significant progress next-generation sequencing (NGS) techniques has broadened knowledge regarding profile tissues blood patients. this scenario, pre-clinical clinical studies suggested members miR-584 family, i.e., miR-584-5p -3p, prominent players development progression. Under some conditions, under-expressed acting tumor suppressors, while other they overexpressed, oncogenes increasing aggressive behavior cells. The aim review to provide comprehensive up-to-date overview on expression, upstream genes, molecular targets signaling pathways influenced by family (i.e., miR-584-3p -5p) various human solid hematological cancers. To achieve goal, 64 articles topic discussed. articles, 55 focused miR-584-5p, it outlined how miRNA could be used future applications potential new therapeutic strategy diagnostic tool.

Language: Английский

Citations

3
Effects of 630 nm laser on apoptosis, metastasis, invasion and epithelial-to-mesenchymal transition of human lung squamous cell carcinoma H520 cells mediated by hematoporphyrin derivatives DOI
Tingting Liu,

Enhua Zhang,

Shichao Cui

et al.

Lasers in Medical Science, Journal Year: 2024, Volume and Issue: 39(1)

Published: Aug. 30, 2024

Language: Английский

Citations

0