Online and personalised control of the Depth of hypnosis during induction using fractional order PID DOI Creative Commons
Marcian Mihai, Isabela Birs, Erwin Hegedus

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

The integration of information technology and control engineering has significantly increased in clinical practice research, especially the management drug dosing for general anaesthesia. main focus research is to achieve a personalised Depth Hypnosis based on novel approach. primary objective regulate Bispectral Index by administering Propofol during hypnotic phase A fractional order time delay model proposed replace conventional PK-PD model. This estimated online induction phase. Proportional-Integral-Derivative (PID) controller then individually tuned each patient. closed loop simulation results demonstrate that controllers effectively minimise undershoot short reach desired time-to-target majority patients. analysis indicates capable maintaining BIS signal within safe range. Comparative analyses with similar are provided contextualise this study existing literature. Disturbance rejection tests maintenance performed effectiveness control. adaptation brings, compared previous attempts, allows improved hypnosis

Language: Английский

Online and personalised control of the Depth of hypnosis during induction using fractional order PID DOI Creative Commons
Marcian Mihai, Isabela Birs, Erwin Hegedus

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

The integration of information technology and control engineering has significantly increased in clinical practice research, especially the management drug dosing for general anaesthesia. main focus research is to achieve a personalised Depth Hypnosis based on novel approach. primary objective regulate Bispectral Index by administering Propofol during hypnotic phase A fractional order time delay model proposed replace conventional PK-PD model. This estimated online induction phase. Proportional-Integral-Derivative (PID) controller then individually tuned each patient. closed loop simulation results demonstrate that controllers effectively minimise undershoot short reach desired time-to-target majority patients. analysis indicates capable maintaining BIS signal within safe range. Comparative analyses with similar are provided contextualise this study existing literature. Disturbance rejection tests maintenance performed effectiveness control. adaptation brings, compared previous attempts, allows improved hypnosis

Language: Английский

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