The secretory Inka cell of the Drosophila larval trachea has a molecular profile similar to that of neurons DOI Creative Commons
Thomas Roeder, Judith Bossen, Xiao Niu

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 1, 2024

Abstract The remarkable architecture of their respiratory system enables the unique metabolic performance that makes insects so successful. We performed single-cell RNAseq analysis larval tracheal Drosophila melanogaster and identified 17 cell populations are part or closely associated with trachea. In addition to several groups epithelial cells different progenitor types, secretory Inka showed unexpected properties. These express almost all molecular elements presynaptic active zone neurotransmitter vesicle release machinery, both characteristic features neurons. Some these essential for function. addition, we could molecularly map types developmental stages. data collected in this work represents a valuable resource future studies focusing on critical organ. most important finding study is have neuron-like properties, which challenges traditional picture distinction between neuronal non-neuronal cells.

Language: Английский

The neuroendocrine and endocrine systems in insect – Historical perspective and overview DOI
Ian Orchard, Angela B. Lange

Molecular and Cellular Endocrinology, Journal Year: 2023, Volume and Issue: 580, P. 112108 - 112108

Published: Nov. 11, 2023

Language: Английский

Citations

11
The secretory Inka cell of the Drosophila larval trachea has a molecular profile similar to that of neurons DOI Creative Commons
Thomas Roeder, Judith Bossen, Xiao Niu

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 1, 2024

Abstract The remarkable architecture of their respiratory system enables the unique metabolic performance that makes insects so successful. We performed single-cell RNAseq analysis larval tracheal Drosophila melanogaster and identified 17 cell populations are part or closely associated with trachea. In addition to several groups epithelial cells different progenitor types, secretory Inka showed unexpected properties. These express almost all molecular elements presynaptic active zone neurotransmitter vesicle release machinery, both characteristic features neurons. Some these essential for function. addition, we could molecularly map types developmental stages. data collected in this work represents a valuable resource future studies focusing on critical organ. most important finding study is have neuron-like properties, which challenges traditional picture distinction between neuronal non-neuronal cells.

Language: Английский

Citations

1