Choline Kinase Alpha Regulates Autophagy-associated Exosome Release to Promote Glioma Cell Progression DOI Creative Commons

J Li,

Yang Zhao, Xiao Wu

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 746, P. 151269 - 151269

Published: Dec. 31, 2024

Language: Английский

Extracellular vesicles in uveal melanoma - biological roles and diagnostic value DOI Creative Commons
Ornella Urzì, Roger Olofsson Bagge, Rossella Crescitelli

et al.

Cancer Letters, Journal Year: 2025, Volume and Issue: unknown, P. 217531 - 217531

Published: Feb. 1, 2025

Language: Английский

Citations

0
Neutrophil- and Endothelial Cell-Derived Extracellular Microvesicles Are Promising Putative Biomarkers for Breast Cancer Diagnosis DOI Creative Commons

Thayse Batista Moreira,

Marina Malheiros Araújo Silvestrini,

Ana Luiza de Freitas Magalhães Gomes

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 587 - 587

Published: Feb. 27, 2025

Introduction: Breast cancer (BC) is a disease that affects about 2.2 million people worldwide. The prognosis and treatment of these patients depend on clinical histopathologic staging, in which more aggressive cancers need less conservative therapeutic approach. Previous studies showed with BC have an increased frequency systemic microvesicles (MVs) are associated invasion, progression, metastasis, can be used liquid biopsy to predict the response individualized treatment. Objective: This study proposes development minimally invasive diagnostic panel follow-up biomarkers as complementary method screen patients. Methods: quantification circulating MVs 48 healthy women 100 who attended Mário Penna Institute between 2019 2022 was performed by flow cytometry. In addition, were analyzed before 6, 12, 24 months post-treatment. Machine learning approaches employed determine performance identify propose classifier algorithms. Results: Patients had neutrophil- endothelial cell-derived than controls After treatment, all MV populations decreased compared pre-treatment, but leukocyte- erythrocyte-derived at 12 after decreasing again months. Conclusions: Performance analyses machine pointed out from neutrophils cells best candidates for biomarkers. Neutrophil- putative screening tests diagnosis.

Language: Английский

Citations

0
Multiplex Detection of Biomarkers Empowered by Nanomaterials DOI Creative Commons
Zongbo Li, Mingquan Guo, Wenwan Zhong

et al.

Precision Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

Citations

0
Choline Kinase Alpha Regulates Autophagy-associated Exosome Release to Promote Glioma Cell Progression DOI Creative Commons

J Li,

Yang Zhao, Xiao Wu

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 746, P. 151269 - 151269

Published: Dec. 31, 2024

Language: Английский

Citations

0