Cited by Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Photocontrollable DNA Walker-Based Molecular Circuit for the Tunable Detection of MicroRNA-21 Using Metal–Organic Frameworks as Label-Free Fluorescence Tags DOI

Jiang Xue Dong, Sai Zhang,

Yan Lei Li

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(45), P. 16744 - 16753

Published: Nov. 6, 2023

Tunable detection of microRNA is crucial to meet the desired demand for sample species with varying concentrations in clinical settings. Herein, we present a DNA walker-based molecular circuit miRNA-21 (miR-21) tunable dynamic ranges and sensitivity levels ranging from fM pM. The phosphate-activated fluorescence UiO-66-NH2 metal-organic framework nanoparticles was used as label-free tags due their competitive coordination effect Zr atom, which significantly inhibited ligand-to-metal charge transfer. To achieve performance miR-21, ultraviolet sensitive o-nitrobenzyl induced photocleavable linker, inserted at various sites between loop stem hairpin probe regulate strand displacement reaction. range can be precisely regulated 700- 67,000-fold limits 2.5 36.7 Impressively, Boolean logic tree complex were constructed computation cancer diagnosis blood samples. This intelligent biosensing method presents powerful solution converting systems into actionable healthcare decisions will facilitate early disease diagnosis.

Language: Английский

Citations

Biosupercapacitors with minimized Self-Discharge DOI

Tapan Dey, Asia Dial, Peter R. Corridon

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 470, P. 144101 - 144101

Published: June 15, 2023

Conventional self-charging biosupercapacitor (BSC) systems are derived from electron transfer via two redox polymers that adapt the associated potentials and define open circuit voltage. This process delivers a high-power pulsed output stable cycling performance. BSCs rely on simultaneous mediation in both electrodes. However, Nernstian include glucose dehydrogenase bilirubin oxidase for oxidation O2 reduction bioanode biocathode, respectively. In such systems, charge is stored as difference activity ratio of aOs+3/aOs+2 polymer The gradient BSC abates during discharge. Meanwhile, throughout recharging or process, potential changes electrodes follow Nernst equation, mid-point equilibrium to non-equilibrium states, by reverting Em fully discharged mode. Herein, state-of-the-art with critical features limitations assessed showing capacitor cell integration between polymers, redox-active species, corresponding Faradaic signals enzymatic based potentially limitless source. Thus, using slaughterhouse waste model, intrinsic parameters emphasized, charging/leakage current ratio, bioelectrode at equilibrium, limiting electrode versus capacitance examine its an energy

Language: Английский

Citations

Isothermal strand displacement polymerase reaction (ISDPR)-assisted microchip electrophoresis for highly sensitive detection of cancer associated microRNAs DOI

Jingyi Chen, Jingzi Zhang,

Qihui Xie

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1300, P. 342469 - 342469

Published: March 12, 2024

Language: Английский

Citations

Miniaturized Power-Integrated and Self-Powered Sensor Systems for Advanced Biomedical Applications DOI

Jeongse Yun,

S. Keerthana,

Seung‐Ryong Kwon

et al.

Sensors and Actuators Reports, Journal Year: 2024, Volume and Issue: unknown, P. 100260 - 100260

Published: Nov. 1, 2024

Language: Английский

Citations

Nanomaterials promote the fast development of electrochemical MiRNA biosensors DOI

Ruizhuo Ouyang, Ying Huang, Yuanhui Ma

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(25), P. 17929 - 17944

Published: Jan. 1, 2024

Representation of traditional detection methods and amplification strategies for the miRNA, application different types nanomaterials in electrochemical miRNA biosensors.

Language: Английский

Citations