Two-pronged strategy: A mitochondria targeting AIE photosensitizer for hydrogen sulfide detection and type I and type II photodynamic therapy DOI

Jizhong Shi,

Manshan Liang,

Yeting Qiu

et al.

Talanta, Journal Year: 2024, Volume and Issue: 282, P. 127074 - 127074

Published: Oct. 18, 2024

Language: Английский

Triggered “On/off” Luminescent Polypeptide Bowl‐Shaped Nanoparticles for Selective Lighting of Tumor Cells DOI Open Access

Yaning Gao,

Yin Wang, Jinhui Jiang

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Abstract Functional polymeric nanoparticles, especially those with anisotropic structures, have shown significant potential and advantages in biomedical applications including detecting, bioimaging, antimicrobial anticancer. Herein, tetraphenylethylene (TPE) azobenzene modified polypeptides of poly(( L ‐glutamic acid) tetraphenylethylene‐ stat ‐( acid)) (P(GATPE 9 ‐ ‐GA 25 )) azobenzene‐ (P(GAAzo 5 29 ) are synthesized, which self‐assemble into bowl‐shaped nanoparticles (BNPs) controlled diameter, opening size fluorescent property individually, or by co‐assembly. Due to the quenching effect azobenzene, fluorescence coassembled BNPs is completely inhibited. Upon incubated under reduction environment, re‐excited owing break azo bonds. Benefiting from high‐level reductase hypoxic liver cancer cells comparing normal cells, quenched exhibit pronounced signal human hepatoma (HepG2) condition, demonstrating high efficiency reduction‐responsive luminescent for selective screening tumor cells. In addition, it also found that a proper promotes cellular uptake even up micron. Overall, this study provides fresh perspective preparation efficient cell screening.

Language: Английский

Citations

4
H2S‐Activated Near‐Infrared Emission Chemiluminescent Probes for Precise Diagnosis of Inflammations and Tumors DOI Creative Commons

Mengke Liang,

Ling’e Zhang, Bo Yu

et al.

Aggregate, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

ABSTRACT Compared to fluorescence imaging, chemiluminescence imaging does not need external excitation light, and hence presents high depth signal‐to‐noise ratio without autofluorescence phototoxicity, making it a promising tool for biological detection analysis. However, the target‐specific activatable near‐infrared emission chemiluminescent probes still be developed precise diagnosis of diseases. In this paper, we synthesized four direct Schaap's chemiluminophores (AINCL, AIFCL, ABTCL, APYCL) by incorporating different electronic acceptors, respectively, studied effect acceptors on optical properties chemiluminophores. To achieve specific hydrogen sulfide (H 2 S)‐related diseases, used H S‐cleavable 2,4‐dinitrophenylsulfonate cage phenol groups in It was demonstrated that endogenous S inflammations tumors could activate effectively with specificity, which provided location nidus allowed us perform surgical resection.

Language: Английский

Citations

2
A coumarin-based near infrared fluorescent probe for the detection of hydrogen sulfide/sulfur dioxide and mitochondrial viscosity DOI
Haiwei Liu,

Mengyao Yuan,

Yanjin Wang

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 418, P. 136243 - 136243

Published: July 4, 2024

Language: Английский

Citations

14
Dual-response fluorescent triphenylamine chemoprobe HN2 for the detection of Cu2+ ions and H2S: Applications in real samples and biological imaging DOI

Ya-Tong Liu,

Qianqian Zhang, Jingyi Li

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 480, P. 143846 - 143846

Published: March 14, 2025

Language: Английский

Citations

0
On-site quantitative measurement of hydrogen sulfide in crop and food samples using a ratiometric near-infrared fluorescent probe coupled with a portable optical data acquisition device DOI
Rumeng Zhang,

Qiwei Zhao,

Yuqing Wang

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113645 - 113645

Published: April 1, 2025

Language: Английский

Citations

0
Microneedle biosensor for real-time monitoring of hydrogen sulfide release from paraventricular nucleus of hypertension rats stimulated by electroacupuncture DOI

Jiameng Pei,

Lina Tang, Chi Jung Kang

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128215 - 128215

Published: April 30, 2025

Language: Английский

Citations

0
Win-win integration: A mitochondria targeted AIE photosensitizer for hypochlorite detection and type I & type II photodynamic therapy DOI

Jiahao Ni,

L.H. Yu, Yixuan Wang

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1320, P. 343035 - 343035

Published: July 28, 2024

Language: Английский

Citations

3
Dual-locked NIR fluorescent probe for detection of GSH and lipid droplets and its bioimaging application in cancer model DOI
Jing-can Qin, F.M. Kong, Dachuan Zhang

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 327, P. 125395 - 125395

Published: Nov. 10, 2024

Language: Английский

Citations

3
Design and characterization of a Near-Infrared Fluorescent Probe SCN for selective detection of Hydrogen Sulfide (H2S) in living systems and food samples DOI
Chen Wang,

Yuran Gui,

Menghuai Wu

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 410, P. 125522 - 125522

Published: July 20, 2024

Language: Английский

Citations

2
A multifunctional probe that responds sequentially to hydrogen sulfide and hypochlorous acid DOI
Feng Li,

Bang-Zhao Zhou,

Shou-Kang Sun

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 111945 - 111945

Published: Oct. 1, 2024

Language: Английский

Citations

1