
Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: March 22, 2025
Monitoring apoptosis in breast cancer cells is crucial for understanding the molecular mechanisms underlying and evaluating therapeutic effects of anticancer drugs. Real-time monitoring p21 mRNA Bax during offers a valuable tool assessing drug efficacy. Tetrahedral DNA frameworks (TDFs) are known their ease synthesis multiple signal outputs. Leveraging these properties, this study developed dual-color probes (DDCPs) real-time cells. In presence mRNA, strand displacement reactions within DDCPs restore Cy5 FAM fluorescence signals, respectively. This strategy consistent with results RT-qPCR studies. Moreover, allow specific investigation apoptotic pathways influenced by different drugs using distinct fluorescent signals pathway differentiation. method holds promise as powerful investigating cells, uncovering associated signaling pathways, screening potential
Language: Английский
Citations
0Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: unknown, P. 126110 - 126110
Published: March 1, 2025
Language: Английский
Citations
0Talanta, Journal Year: 2025, Volume and Issue: unknown, P. 128033 - 128033
Published: March 1, 2025
Language: Английский
Citations
0Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101763 - 101763
Published: April 1, 2025
Language: Английский
Citations
0Talanta, Journal Year: 2024, Volume and Issue: 282, P. 127033 - 127033
Published: Oct. 13, 2024
Language: Английский
Citations
3Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Citations
1