The Role of Blastocystis spp. in the Etiology of Gastrointestinal and Autoimmune Diseases

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 313 - 313

Published: March 25, 2025

Blastocystis spp. has been linked to gastrointestinal symptoms, yet its pathogenicity remains uncertain. In addition, the roles of virulence factors, pathogenic potential, and host-specific traits associated with symptomatic infections are still not well understood. The growing number immunocompromised patients contributed an increasing prevalence infections, which may be implicated in development various inflammatory diseases, including irritable bowel syndrome (IBS), colorectal cancer, autoimmune disorders such as Hashimoto’s disease ulcerative colitis. However, presence nonspecific symptoms often complicates diagnosis. This study aimed present current data on impact progression explore potential treatment options for infections. A literature review was conducted analyze role pathogenesis specific diseases investigate mechanisms interaction host organism. Advances diagnostic techniques, particularly PCR, allow only detection but also identification subtypes, improving precision. Beyond conventional therapies like metronidazole, there is a emphasis alternative treatments, use medicinal plants probiotics.

Language: Английский

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Blastocystis spp. Infection in Kidney Transplant Recipient

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 341 - 341

Published: April 1, 2025

The Blastocystis sp. is a common enteric parasite found in humans and various animals. spp. infections may be asymptomatic or symptomatic, with gastrointestinal extra-intestinal symptoms, such as diarrhea, nausea, abdominal pain, bloating, vomiting, anorexia. disease leading to symptoms usually observed participants immune deficiency. We report the case of weight loss diarrhea infection 64-year-old renal transplant recipient.

Language: Английский

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Targeted-Amplicon NGS for Blastocystis sp. in Shepherd Dogs of Portugal Discriminates Co-Colonization with Multiple Zoonotic Subtypes

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 325 - 325

Published: April 2, 2025

Research on endoparasites in pet dogs has been growing, but shepherd have largely overlooked. These frequently share close proximity not only with sheep, which are reservoirs of zoonotic subtypes Blastocystis, also their owners. This contact increases the potential for to act as intermediates transmission Blastocystis. To clarify role these this parasite, study investigated presence Blastocystis dogs. Stool samples from Portuguese were analyzed using SYBR-Green-based real-time PCR and melting curve analysis followed by targeted-amplicon NGS mixed infections detection. Our results revealed a 60% occurrence sp. dog stools frequent identification ST1–ST4 ST14. Additionally, we observed subtype diversity within individual dogs, suggesting cross-species between livestock humans.

Language: Английский

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Occurrence and Genotypic Identification of Blastocystis spp. and Enterocytozoon bieneusi in Bamaxiang Pigs in Bama Yao Autonomous County of Guangxi Province, China

Animals, Journal Year: 2024, Volume and Issue: 14(22), P. 3344 - 3344

Published: Nov. 20, 2024

spp. and

Language: Английский

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Epidemiology of Blastocystis in farm animals: a review

Veterinary Parasitology, Journal Year: 2024, Volume and Issue: 334, P. 110382 - 110382

Published: Dec. 25, 2024

Language: Английский

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