Yellow Fever in Non-Human Primates: A Veterinary Guide from a One Health Perspective DOI Creative Commons
Remco A. Nederlof, Tommaso Virgilio,

Hendrickus J. J. Stemkens

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 339 - 339

Published: April 6, 2025

Yellow fever (YF) causes severe morbidity and mortality in Africa South America. It is an arthropod-borne viral disease endemic to tropical regions of virus (YFV) transmitted by mosquitoes frequently affects both non-human primates (NHPs) humans. Neotropical (NTPs) are generally more severely afflicted YFV than African primates. Asian appear not be susceptible this disease. Susceptibility varies among NTP species: asymptomatic infections described some species, whereas epizootic events others. The genus Alouatta (howler monkeys) considered the most NTPs. Epizootic resulting death thousands NTPs have been recorded recent history. As a result, poses threat survival species. In cases, found dead without showing prior clinical signs. cases where signs observed, they mostly non-specific. Due their high susceptibility, used as epidemiological predictors for human YF outbreaks. infection may diagnosed means isolation, reverse transcription polymerase chain reaction, serology, histopathology, or immunohistochemistry. Animals that survive develop neutralizing antibodies YFV. Currently, no specific treatment available. Sustained control strategies must rely on surveillance accurate diagnostics allow early detection outbreaks rapid implementation measures. Prophylaxis should based One Health perspective recognizes intricate interplay between health, primate environment. Vaccines available, with 17DD vaccine effectively preventing However, mitigation continue vector control, preferably using eco-friendly methods. Climate change activities, impact local ecology, assumed increase risk transmission next decades.

Language: Английский

Seroprevalence of Chikungunya and O'nyong‐nyong Viruses in Senegal, West Africa DOI Creative Commons
Prince Baffour Tonto, Mouhamad Sy, Ibrahima Ndiaye

et al.

Journal of Medical Virology, Journal Year: 2025, Volume and Issue: 97(3)

Published: March 1, 2025

ABSTRACT Arthritogenic alphaviruses such as chikungunya (CHIKV) and o'nyong‐nyong (ONNV) viruses have shown capacity to cause widespread epidemics, with recurrent sporadic outbreaks occurring throughout sub‐Saharan Africa. We analyzed the seroprevalence for CHIKV ONNV in 470 non‐febrile subjects from three regions Senegal (Sindia, 2018; Thies, Kedougou, 2022/2023) using retrospective samples. assessed presence of anti‐CHIKV IgG neutralizing antibody titers against via enzyme‐linked immunosorbent assay (ELISA) microneutralization tests, respectively, determined risk factors exposure by binary logistic regression. The overall alphavirus based on an virus like particle (VLP) ELISA was 38.5%, rates varying geographically: Kedougou (48.6%), Thies (31.9%), Sindia (14.9%). Neutralizing revealed 7.4% 9.8%, significant variations region age group. Cross‐reactivity analysis showed that 82.9% cases exhibited a response ONNV, while 71.7% cross‐neutralized CHIKV. Residents had significantly higher odds infection (aOR, 3.147; 95% CI: 1.164–8.510) more likely 3.888; 1.319–11.466). Furthermore, older (> 40 years) factor both 2.094; 0.846–5.185) 2.745; 1.212–6.216). Our study confirms co‐circulation Senegal, highlighting their geographic demographic distribution. These findings underscore need continued surveillance, testing, tailored public health strategies mitigate impact Senegal.

Language: Английский

Citations

1
Wolbachia: A Bacterial Weapon Against Dengue Fever- A Narrative Review of Risk Factors for Dengue Fever Outbreaks DOI Creative Commons

Sepehr Safaei,

Mozhgan Derakhshan-sefidi,

Ali Karimi

et al.

New Microbes and New Infections, Journal Year: 2025, Volume and Issue: unknown, P. 101578 - 101578

Published: March 1, 2025

Arboviruses constitute the largest known group of viruses and are responsible for various infections that impose significant socioeconomic burdens worldwide, particularly due to their link with insect-borne diseases. The increasing incidence dengue fever in non-endemic regions underscores urgent need innovative strategies combat this public health threat. Wolbachia, a bacterium, presents promising biological control method against mosquito vectors, offering novel approach managing fever. We systematically investigated biomedical databases (PubMed, Web Science, Google Scholar, Science Direct, Embase) using "AND" as Boolean operator keywords such "dengue fever," virus," "risk factors," "Wolbachia," "outbreak." prioritized articles offered insights into risk factors contributing outbreak provided an overview Wolbachia's characteristics functions disease management, considering studies published until December 25, 2024. Field experiments have shown introducing Wolbachia-infected mosquitoes can effectively reduce populations lower transmission rates, signifying its potential practical controlling disease.

Language: Английский

Citations

0
Patterns of Insect Distribution in Fruit Trees of South Romania and Their Role as Bacterial Vectors DOI Creative Commons

Dana S. Copoiu,

Paris Lavín, Corina Iţcuş

et al.

Diversity, Journal Year: 2025, Volume and Issue: 17(4), P. 295 - 295

Published: April 20, 2025

This study is the first investigation of tree–insect–bacteria interactions in southern Romania, documenting distribution 19 insect species across various fruit trees and their insect-associated bacterial diversity. Insect were identified through DNA barcoding, while communities Anthomyia, Botanophila, Drosophila, Scaptomyza insects analyzed via 16S rRNA gene sequencing. diversity varied apple, cherry, plum, peach, quince trees, with most showing tree-specific distribution, except for Drosophila melanogaster, which was found on all tree species. Its presence primarily influenced by development stages rather than temperature changes. comprised 51 genera four phyla, predominantly Pseudomonadota Bacillota, that species, suggesting potential role these flies as vectors. Several pathogenic biomarkers within microbiomes, involvement disease transmission, particularly affecting apple cherry trees. also provides report seven being microbiome characterization dipteran associated regional

Language: Английский

Citations

0
Yellow Fever in Non-Human Primates: A Veterinary Guide from a One Health Perspective DOI Creative Commons
Remco A. Nederlof, Tommaso Virgilio,

Hendrickus J. J. Stemkens

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 339 - 339

Published: April 6, 2025

Yellow fever (YF) causes severe morbidity and mortality in Africa South America. It is an arthropod-borne viral disease endemic to tropical regions of virus (YFV) transmitted by mosquitoes frequently affects both non-human primates (NHPs) humans. Neotropical (NTPs) are generally more severely afflicted YFV than African primates. Asian appear not be susceptible this disease. Susceptibility varies among NTP species: asymptomatic infections described some species, whereas epizootic events others. The genus Alouatta (howler monkeys) considered the most NTPs. Epizootic resulting death thousands NTPs have been recorded recent history. As a result, poses threat survival species. In cases, found dead without showing prior clinical signs. cases where signs observed, they mostly non-specific. Due their high susceptibility, used as epidemiological predictors for human YF outbreaks. infection may diagnosed means isolation, reverse transcription polymerase chain reaction, serology, histopathology, or immunohistochemistry. Animals that survive develop neutralizing antibodies YFV. Currently, no specific treatment available. Sustained control strategies must rely on surveillance accurate diagnostics allow early detection outbreaks rapid implementation measures. Prophylaxis should based One Health perspective recognizes intricate interplay between health, primate environment. Vaccines available, with 17DD vaccine effectively preventing However, mitigation continue vector control, preferably using eco-friendly methods. Climate change activities, impact local ecology, assumed increase risk transmission next decades.

Language: Английский

Citations

0