Graphene-Based Photodynamic Therapy and Overcoming Cancer Resistance Mechanisms: A Comprehensive Review DOI Creative Commons
Hanna Dilenko, Kateřina Tománková, Lucie Válková

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 5637 - 5680

Published: June 1, 2024

Abstract: Photodynamic therapy (PDT) is a non-invasive that has made significant progress in treating different diseases, including cancer, by utilizing new nanotechnology products such as graphene and its derivatives. Graphene-based materials have large surface area photothermal effects thereby making them suitable candidates for PDT or photo-active drug carriers. The remarkable photophysical properties of derivates facilitate the efficient generation reactive oxygen species (ROS) upon light irradiation, which destroys cancer cells. Surface functionalization can also enhance their biocompatibility anticancer activity. paper delves into distinct roles played graphene-based photosensitizers (PS) carriers while at same time considers how these could be used to circumvent resistance. This will provide readers with an extensive discussion various pathways contributing inefficiency. Consequently, this comprehensive review underscores vital derivatives may play emerging strategies treatment other medical purposes. With better comprehension current state research existing challenges, integration holds great promise developing targeted, effective, personalized treatments. Keywords: quantum dots, oxide, research, photosensitizers, delivery

Language: Английский

2D material-based sensing devices: an update DOI Creative Commons
Jahan Zeb Hassan, Ali Raza, Zaheer Ud Din Babar

et al.

Journal of Materials Chemistry A, Journal Year: 2023, Volume and Issue: 11(12), P. 6016 - 6063

Published: Jan. 1, 2023

2D structures have numerous attributes that make them effective for the fabrication of sensing devices. The aim this review is to provide an update on recent developments in field sensor devices made from atomically thin materials.

Language: Английский

Citations

63

Review on Healthcare Biosensing Nanomaterials DOI
Alok Tripathi, José Bonilla‐Cruz

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(7), P. 5042 - 5074

Published: March 31, 2023

Fast technological progress has sped up the growth of telemedicine, mobile e-health services, and healthcare monitoring, which, nowadays, are technologies in high demand medical field analytical sensing. Biosensing device design promoted forefront research topics wherein new sensing have been developed. In this regard, nanomaterials had a crucial role novel biosensors based on emerged as detective tools for several biomolecules. Most remarkably sensitive selective to detect cancer biomarkers, toxins foods, drugs, pathogenic microorganisms, cholesterol, pesticides, nucleic acids, glucose, heavy-metal contaminations, other bioanalytes under different platforms at extraordinarily low concentrations (nanomolar, picomolar, or femtomolar). A comprehensive review used biosensing is offered herein. Specifically, offers point view, highlighting covering exhaustively kinds (<500 nm) human diseases through biosensing. sense, we organize them into organic, inorganic, carbon-based, thus offering guide selecting best nanomaterial specific detection. Further, it provides roadmap real-time utilization commercial scale. Also, addresses some aspects use applications The discussed paper highlights immense potential implement nanocomposites initial examination point-of-care testing.

Language: Английский

Citations

56

Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin DOI
Guangli Li,

Xuan Wan,

Yonghui Xia

et al.

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(18), P. 17040 - 17052

Published: Sept. 6, 2023

The excessive use of levofloxacin (LEV) can lead to significant environmental pollution, while also damaging human health. accurate detection its concentration is therefore essential protect both the environment and Herein, we report simple synthesis α-zirconium phosphate supported on nitrogen-doped graphene nanosheets (α-ZrP/NG) application in voltammetric determination trace LEV real samples. surface morphology, microstructure, electrochemical properties α-ZrP/NG were investigated by microscopic spectroscopic techniques. analytical parameters, including accumulation potential, time, loading volume, buffer pH, optimized improve electrocatalytic sensing performance α-ZrP/NG. Owing synergetic interaction between α-ZrP NG, proposed sensor exhibited an excellent activity for electrical oxidation LEV. In range 0.01–5.0 μM, anodic peak current increased linearly with increase concentration, limit was 2.6 nmol L–1. Finally, levels wastewater, serum, milk, eye drop samples determined using system combined a glassy carbon electrode give satisfactory recoveries (98.48–103.2%), indicating that prepared demonstrates promise environmental, food, drug monitoring applications.

Language: Английский

Citations

56

Nanohybrid SERS substrates intended for food supply chain safety DOI
Bingzhi Li, Sijie Liu, Lunjie Huang

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 494, P. 215349 - 215349

Published: July 28, 2023

Language: Английский

Citations

53

Enzyme-responsive microneedle patch for bacterial infection and accelerated healing of diabetic wounds DOI
Shizhou Wu,

Boquan Qin,

Xiaofang Tang

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 466, P. 143126 - 143126

Published: April 30, 2023

Language: Английский

Citations

49

A facile and efficient voltammetric sensor for marbofloxacin detection based on zirconium-based metal-organic framework UiO-66/nitrogen-doped graphene nanocomposite DOI
Tianyu Wang, Yonghui Xia,

Xuan Wan

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 201, P. 110673 - 110673

Published: May 1, 2024

Language: Английский

Citations

42

Recent developments on graphene oxide and its composite materials: From fundamentals to applications in biodiesel synthesis, adsorption, photocatalysis, supercapacitors, sensors and antimicrobial activity DOI Creative Commons

Nituraj Mushahary,

Angita Sarkar,

Fungbili Basumatary

et al.

Results in Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: 15, P. 100225 - 100225

Published: May 1, 2024

Graphene oxide (GO), a 2-dimensional (2-D) monolayer of graphite, has drawn lot importance due to its accessibility and material compatibility. It can be produced by mechanically stirring or sonicating graphite exfoliate it into layered sheets. Due high stability, 2-D planar structure, huge surface area, easy chemical adaptation via functionalities, efficient loading with many biomolecules, optical, electrical, mechanical capabilities, GO derivatives are quickly emerging as the most intensely studied carbon-based materials in number fields. In this review, we provided thorough overview GO, synthesis pristine GO-based composites well their applications field biodiesel synthesis, adsorption, photodegradation, electrochemical along biological significance antimicrobial efficiency. Owing distinctive features, garnered interest realm catalyst. The process transesterification using supported catalyst is highlighted herein. Similarly, adsorption photodegradation several organic dyes effluents also discussed article. Finally, derived relation attractive trends highlighting future scope commercial implications.

Language: Английский

Citations

23

Terahertz Plasmonic Biosensor Leveraging Ag-Au-Graphene Heterostructures for Quantitative Hemoglobin Analysis with Machine Learning Algorithms for Performance Optimization DOI
Jacob Wekalao,

Ngaira Mandela,

Costable Lefu

et al.

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 4, 2024

Language: Английский

Citations

19

Development of a High-Sensitivity Graphene-Metal Nanocomposite Metasurfaces Biosensor with Machine Learning Integration for Rapid Detection of Waterborne Pathogens with Behaviour Prediction Leveraging Stacking Ensemble Regressor DOI
Jacob Wekalao

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Language: Английский

Citations

14

Design of a High-Performance Surface Plasmon Resonance Sensor for Precise Detection of Alcoholic Compounds in Forensic and Medical Applications DOI
Jacob Wekalao, Shobhit K. Patel, Ammar Armghan

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Language: Английский

Citations

14