Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 372, P. 386 - 402
Published: June 25, 2024
Language: Английский
Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 372, P. 386 - 402
Published: June 25, 2024
Language: Английский
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: March 18, 2025
Language: Английский
Citations
0PeerJ, Journal Year: 2025, Volume and Issue: 13, P. e19332 - e19332
Published: April 24, 2025
Tumors pose a serious threat to global public health and are usually treated from two aspects: tumor cells microenvironment. Compared with traditional chemotherapy drugs, Chinese medicine (TCM) monomers have advantages in treatment, such as multiple targets, levels synergistic intervention. However, most TCM active ingredients disadvantages poor water solubility stability, which restrict their clinical application. Nano drug delivery systems the functions of improving bioavailability anti-tumor ingredients, enhancing tissue targeting, achieving controlled release, inhibiting multidrug resistance. free monomers, they higher therapeutic effects fewer side effects. This article summarizes five commonly used monomer nanocarriers, including lipid nanomaterials, exosomes, polymer micelles, carbon nanotubes, dendrimers, explains mechanisms after combining TCM, cell proliferation metastasis, regulating microenvironment, etc . At same time, potential nano combined radiotherapy immunotherapy is discussed, well current problems toxicity, long-term complex amplification process, future development directions, aiming provide reference for promoting application ingredients.
Language: Английский
Citations
0Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 179, P. 207 - 219
Published: March 20, 2024
Language: Английский
Citations
3Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: April 1, 2024
Ultrasound-enabled nanomedicine leverages ultrasound to amplify the capabilities of engineered nanosystems, paving way for innovative diagnostic and therapeutic breakthroughs in conventional nanomedicine. As a burgeoning discipline, past overviews have sometimes offered fragmented perspective, lacking comprehensive view. This review presents systematic exploration latest advancements ultrasound-enabled nanomedicine, with particular emphasis on oncology. Covered topics include molecular imaging tumors, separation tumor markers, penetration through physiological barriers, perforation cell membranes, targeted drug release activation strategies, an array sonotherapies oncological treatments. We delve into research framework each topic, foundational design their associated mechanisms. Moreover, we highlight recent pivotal aimed at deepening reader's understanding this intricate domain. underscores integration theories within aspiring ignite advanced theoretical insights introduce paradigms. In conclusion, outline current challenges prospective directions. An enhanced focus these areas will expedite advancement
Language: Английский
Citations
3Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 372, P. 386 - 402
Published: June 25, 2024
Language: Английский
Citations
3