Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123142 - 123142
Published: Dec. 16, 2024
Language: Английский
Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 188 - 188
Published: March 8, 2025
Postoperative adhesions are common complications following surgery, often accompanied by pain and inflammation that significantly diminish patients’ quality of life. Moreover, managing postoperative incurs substantial cost, imposing a considerable financial burden on both patients healthcare systems. Traditional anti-adhesion materials confronted with limitations, such as inadequate tissue adherence in moist environment poor degradability, underscoring the urgent need for more effective solutions. Recently, polysaccharide-based hydrogels have received attention their potential preventing adhesions. The not only facilitate wound healing but also effectively reduce inflammation, providing promising approach to This review provides an extensive analysis progress made development therapy. It highlights principal benefits, outlines future research trajectories, addresses ongoing challenges be overcome.
Language: Английский
Citations
0
Small, Journal Year: 2025, Volume and Issue: unknown
Published: March 19, 2025
Abstract Hydrogel microspheres are important in regenerative medicine and tissue engineering, acting as cargos of cells, drugs, growth factors, bio‐inks for 3D printing, medical devices. The antimicrobial anti‐inflammatory characteristics hydrogel good treating injured tissues. However, the biological properties should be modified optimal treatment various body parts with different physiological biochemical environments. In addition, specific preparation methods required to produce customized shapes sizes clinical applications. Herein, advances biomedical applications reviewed. Synthesis precursor solutions, manufacturing methods, strategies enhancing functions these described. involvement bioactive repair is also discussed. This review anticipates fostering more insights into design, production, application biomedicine.
Language: Английский
Citations
0
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 512, P. 162672 - 162672
Published: April 17, 2025
Language: Английский
Citations
0
ChemPlusChem, Journal Year: 2024, Volume and Issue: unknown
Published: June 26, 2024
Supramolecular structures are widespread in living system, which usually spatiotemporally regulated by sophisticated metabolic processes to enable vital biological functions. Inspired tremendous efforts have been made realize spatiotemporal control over the self-assembly of supramolecular materials synthetic scenario coupling chemical reaction with molecular process. In this review, we focused on works related hydrogels that space and time using reaction. Firstly, summarized how spatially controlled can be achieved via reaction-instructed self-assembly, application such a methodology biotherapy was discussed as well. Second, reviewed dynamic dictated networks evolve their properties against time. Third, recent progresses both though reaction-diffusion-coupled approach. Finally, provided perspective further development future.
Language: Английский
Citations
0
Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: 21(6), P. 881 - 904
Published: June 2, 2024
Most therapeutics delivered using short-acting formulations need repeated administration, which can harm patient compliance and raise failure risks related to inconsistent treatment. Injectable long-acting (ILAFs) are controlled/sustained-release fabricated deliver active pharmaceutical ingredients (APIs) extend their half-life over days months. Longer half-lives of ILAFs minimize the necessity for frequent doses, increase compliance, reduce risk side effects from intravenous (IV) infusions. Using ILAF technologies, immediate drug release also be controlled, thereby minimizing potential adverse due high initial blood concentrations.
Language: Английский
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0
Regenerative Therapy, Journal Year: 2024, Volume and Issue: 28, P. 101 - 114
Published: Dec. 6, 2024
Language: Английский
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0
Journal of Biomaterials Applications, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 13, 2024
The Diels-Alder reaction, a classical (4+2) cycloaddition process, holds significant standing within the realms of organic synthesis and polymer chemistry, frequently employed in areas such as pharmaceutical production material science. Recently, hydrogels constructed via reactions have garnered considerable attention from researchers. This review aims to summarize advancements utilizing reaction for hydrogel synthesis, exploring its impact on structural design, functionalization, application domains. Initially, fundamental principles are introduced alongside an examination benefits characteristics fabrication. Subsequently, applications Diels-Alder-generated biomedicine, smart responsive materials, drug delivery systems, among other fields, comprehensively reviewed. Challenges limitations encountered during using this also discussed. Finally, prospective research directions future prospects contemplated.
Language: Английский
Citations
0
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123142 - 123142
Published: Dec. 16, 2024
Language: Английский
Citations
0