Sex disparities in outcome of medication-assisted therapy of opioid use disorder: Nationally representative outpatient clinic data
Drug and Alcohol Dependence,
Journal Year:
2025,
Volume and Issue:
267, P. 112535 - 112535
Published: Jan. 5, 2025
Language: Английский
Cannabinoids and the Gastrointestinal Tract
Clinical Gastroenterology and Hepatology,
Journal Year:
2023,
Volume and Issue:
21(13), P. 3217 - 3229
Published: Sept. 9, 2023
Language: Английский
Substance Use Treatment Completion Among Unhoused Young Adults: A Predictive Modeling Approach
Journal of Drug Issues,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 19, 2024
Background:
Unhoused
young
adults
aged
18–24
years
are
at
increased
risk
of
substance
misuse
relative
to
the
general
population
and
experience
unique
barriers
engaging
in
treatment.
This
study
evaluates
predictors
treatment
completion
for
unhoused
receiving
use
Methods:
Predictive
models
were
generated
on
data
from
2020
Treatment
Episode
Data
Set-Discharges.
The
sample
included
discharges
involving
(
N
=
12,273).
Model
performance
was
assessed
by
inspecting
several
evaluative
metrics.
Results:
Overall,
each
model
performed
relatively
well
(AUC:
0.7234–0.7753).
Classification
trained
balanced
predicted
a
higher
proportion
completers.
Models
also
achieved
accuracy
F1
scores
imbalanced
data.
Conclusions:
Findings
reveal
multiple
features
important
accurate
classification
completion,
which
may
be
useful
developing
individualized
interventions
support
clients’
engagement
services.
Language: Английский
Sex disparities in outcome of medication-assisted therapy of opioid use disorder: Nationally representative study
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 26, 2024
Abstract
Question
The
opioid
epidemic
causes
massive
morbidity,
and
males
have
substantially
greater
overdose
mortality
rates
than
females.
It
is
unclear
whether
there
are
sex-related
disparities
at
different
stages
in
the
trajectory
of
use
disorders,
“real
world”
settings.
Goal
To
determine
sex
non-medical
(NMOU)
end
outpatient
medication-assisted
treatment
(MAT),
using
nationally
representative
data.
Design
Observational
epidemiological
study
publicly
funded
MAT
programs
national
“Treatment
episode
data
set-discharges”
(TEDS-D)
for
2019.
Participants
Persons
aged
≥18
their
first
episode,
heroin
or
other
opioids
(N=11,549).
binary
outcome
was
presence/absence
NMOU.
Results
In
univariate
analyses,
had
significantly
higher
odds
NMOU,
compared
to
females
(odds
ratio=1.27;
Chi
2
[df:1]=39.08;
uncorrected
p<0.0001;
p=0.0041
after
Bonferroni
correction).
A
multivariable
logistic
regression
detected
a
male>female
ratio
1.19
(95%CI=1.09-1.29;
p<0.0001),
adjusting
socio-demographic/clinical
variables.
Several
specific
conditions
were
revealed
which
NMOU
(e.g.,
ages
18-29
30-39;
corrected
p=0.012,
if
they
used
by
inhalation;
p=0.0041).
Conclusions
This
indicates
that
MAT,
indicating
more
unfavorable
outcomes.
reveals
socio-demographic
clinical
variables
under
this
disparity
most
prominent.
Highlights
*
outcomes
therapy
large-scale
study,
adult
month
prior
discharge
from
females,
Males
risk
undesirable
several
younger
age
categories,
route
inhalation.
Sex
occur
can
be
examined
potentially
addressed,
with
goal
improving
personalized
approaches
OUD.
Language: Английский
Trends and variations in admissions for cannabis use disorder among pregnant women in United States
Journal of Perinatal Medicine,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 24, 2024
Abstract
Objectives
Cannabis
use
disorder
(CUD)
among
pregnant
women
is
increasing,
yet
limited
information
exists
on
admissions
for
treatment
in
this
population.
This
study
examined
trends
CUD
publicly
funded
U.S.
facilities
from
2000
to
2021.
Methods
Using
the
Treatment
Episode
Data
Set-Admissions,
we
analyzed
33,729
of
with
CUD.
Descriptive
statistics
were
used
assess
patterns
by
race/ethnicity,
age,
and
co-substance
use.
Results
increased
2.7-fold,
2.3
%
6.2
2009,
followed
a
decrease
4.3
2014,
peak
6.7
2018,
decline
3.0
In
2021,
racial/ethnic
disparities
noted,
higher
proportions
White
(48.8
%)
Black
(32.5
non-Hispanic
compared
Hispanic
(9.6
%).
Admissions
decreased
aged
≤20
years
old
(y/o),
but
≥30
y/o
2010
highest
prevalence
those
21–29
y/o.
Co-substance
use,
particularly
narcotics,
stimulants,
depressants,
hallucinogens,
was
prevalent
2017
Conclusions
have
fluctuated
over
two
decades,
variations
race/ethnicity
age.
These
findings
highlight
need
tailored
interventions
ongoing
adaptation
services
Language: Английский
Predictors of Participation in Prenatal Substance Use Assessment, Counseling, and Treatment Among Pregnant Individuals in Prenatal Settings Who Use Cannabis
Journal of Addiction Medicine,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 15, 2024
Objectives
Assessment
and
counseling
are
recommended
for
individuals
with
prenatal
cannabis
use.
We
examined
characteristics
that
predict
substance
use
assessment
among
who
screened
positive
in
settings.
Methods
Electronic
health
record
data
from
Kaiser
Permanente
Northern
California’s
Early
Start
perinatal
screening,
assessment,
program
was
used
to
identify
≥1
pregnancies
Outcomes
included
completion
of
a
those
assessed,
attendance
only
or
Addiction
Medicine
Recovery
Services
(AMRS)
treatment.
Predictors
demographics
past-year
psychiatric
disorder
diagnoses
evaluated
GEE
multinomial
logistic
regression.
Results
The
sample
17,782
20,398
(1/2011–12/2021).
Most
(80.3%)
had
an
assessment.
Individuals
Medicaid,
anxiety,
depression
tobacco
disorders,
compared
without,
higher
odds
greater
parity,
older
age
(≥35)
later
trimesters,
lower
Among
64%
(n
=
10,469)
needing
intervention
based
on
most
(88%)
attended
AMRS
(with
without
Start).
Greater
parity
trimester
associated
odds,
while
Medicaid
counseling.
Nearly
all
diagnosed
disorders
were
Conclusions
A
comprehensive
engaged
pregnant
Opportunities
improve
care
gaps
remain.
Language: Английский