Herbal Cannabis and Depression: A Review of Findings Published over the Last Three Years DOI Creative Commons
József Haller

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 689 - 689

Published: May 27, 2024

Public perception contrasts scientific findings on the depression-related effects of cannabis. However, earlier studies were performed when cannabis was predominantly illegal, its production mostly uncontrolled, and idea medical incipient only. We hypothesized that recent changes in attitudes legislations may have favorably affected research. In addition, publication bias against also decreased. To investigate this hypothesis, we conducted a review research published over last three years. found 156 relevant articles. most cross-sectional studies, depression higher those who consumed than did not. An increase consumption typically followed by an depression, whereas withdrawal from ameliorated cases. Although reduced none these placebo-controlled. clinical same period, placebo and, average effect size larger investigated plausibility antidepressant reviewing molecular pharmacological studies. Taken together, reviewed do not support herbal

Language: Английский

The adverse public health effects of non-medical cannabis legalisation in Canada and the USA DOI Creative Commons
Tesfa Mekonen Yimer,

Eva Hoch,

Benedikt Fischer

et al.

The Lancet Public Health, Journal Year: 2025, Volume and Issue: 10(2), P. e148 - e159

Published: Feb. 1, 2025

SummaryCannabis consumption is legally prohibited in most countries the world. Several are legalising cannabis for adult consumption. It important to monitor public health effects of these policy changes. In this paper, we summarise evidence date on legalisation non-medical use Canada and USA. We describe regulatory models legalisation, changes products pricing, illicit market, use, cannabis-related physical mental harms. discuss challenges assessing outcomes emphasise importance continuous rigorous monitoring adverse inform design policies regulations.

Language: Английский

Citations

1

High potency cannabis use, mental health symptoms and cannabis dependence: Triangulating the evidence DOI Creative Commons
Kat Petrilli, Lindsey A. Hines, Sally Adams

et al.

Addictive Behaviors, Journal Year: 2023, Volume and Issue: 144, P. 107740 - 107740

Published: April 24, 2023

Cannabis potency (concentration of Δ-9-Tetrahydrocannabinol) has been associated with risks adverse mental health outcomes and addiction but no studies have triangulated evidence from self-report objective measures cannabis potency. We hypothesised that users high would higher levels (a) anxiety, (b) depression (c) psychosis-like symptoms (d) dependence than lower cannabis.A cross-sectional study 410 participants donated a sample for analysis THC concentration reported their preference. These two exposure were investigated association dependence, depression, in separate linear/logistic regression models.High preference was slight increased risk after adjusting confounding, the exception use frequency (OR = 1.16, 95% CI 1.04-1.28). No found between dependence. There weak small anxiety. or symptoms.Users who preferred types might be at problematic use. This should considered caution as we not able to triangulate these results an measure More research is needed understand

Language: Английский

Citations

14

An analysis of the cultivation, consumption and composition of home-grown cannabis following decriminalisation in the Australian Capital Territory DOI Creative Commons
Cilla Zhou, Isobel Lavender, Rebecca Gordon

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 4, 2025

The Australian Capital Territory (ACT), a region that includes Australia's capital, Canberra, decriminalised small-scale cannabis cultivation and possession in January 2020. Here, we examined use behaviours, experiences attitudes of current past ACT cultivators. residents (n = 311) who currently cultivate or have previously cultivated completed cross-sectional online survey ('CAN-ACT') provided home-grown for phytocannabinoid analysis (optional). Reasons included preference to self-supply, enjoyment the process avoiding criminal networks. Cannabis intake was median 1 gram on typical day used number plants grown per year 4. Various challenges were identified, most commonly mould, nutrient deficiency spider mites. samples 71) generally exhibited moderate THC content (mean 8.99 ± SEM 0.51% [w/w]) low CBD (< 0.1%). Few exceeded contaminant guidelines heavy metals pesticides. Respondents identified various grey areas legislation might lead inadvertent activity, many (52%) remained anxious about arrest. In general, recent legislative changes appear support community needs. Options further refinement are discussed.

Language: Английский

Citations

0

Adding Nuance to Understanding the Effects of Cannabis Legalization by Using Policy Bundles: A Study of Youth Mental Health DOI Creative Commons

Shazib Altaf,

Daniel J. Mallinson, Mingean Park

et al.

Substance Use & Misuse, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: Feb. 16, 2025

Background Variation in policy design presents a challenge for understanding the positive and negative externalities of cannabis legalization. We offer an advancement on measuring state variation – bundles demonstrate how measure can be used to test effects legalization youth mental health.

Language: Английский

Citations

0

Cannabis use in association with past 30-day suicide ideation and suicide attempt among university students in northern Morocco DOI Creative Commons

Mohjat Belaatar,

Adil Najdi,

Adil El Ammouri

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Abstract Background: Suicide rates continue to rise, especially among young people, and is considered one of the world's leading causes death. Suicidal ideation represents a significant risk factor for mortality, particularly cannabis users. Aim: The primary objective this study evaluate suicide students, those who use cannabis. Methods: In quantitative study, we utilized M.I.N.I. questionnaire gather data on mental disorders, including suicidal risk. was administered students at Abdelmalek Essaâdi University campus in Tetouan, with an average age 21, which 52.56% were female. Along questionnaire, included background that collected socio-demographic information, history psychoactive substance use, family background, early childhood experiences identify factors associated each disorder under investigation. Results: In sample 1191 322 number presenting prevalence 27.03%, 41.7% are Conclusions: line previous studies, can lead thoughts behaviors.

Language: Английский

Citations

0

Persistent Psychosis Associated With Intravenous Ketamine in a Patient Using Cannabis DOI
Rachel M. Pacilio, Jamarie Geller

Journal of Clinical Psychopharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

University of Michigan, Department Psychiatry, Ann Arbor, MI [email protected] Received December 17, 2024; accepted after revision February 22, 2025.

Language: Английский

Citations

0

A Systematic Review of Cannabis and Anxiety: Chicken or Egg? DOI

Lily G. Blyth,

Chris J. Seal, Maryam Sorkhou

et al.

Current Addiction Reports, Journal Year: 2025, Volume and Issue: 12(1)

Published: April 11, 2025

Language: Английский

Citations

0

Detection of Cannabinoids in Oral Fluid Specimens as the Preferred Biological Matrix for a Point-of-Care Biosensor Diagnostic Device DOI Creative Commons
Călin Trif, Dorin Harpaz, Evgeni Eltzov

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(3), P. 126 - 126

Published: Feb. 27, 2024

An increasing number of countries have started to decriminalize or legalize the consumption cannabis for recreational and medical purposes. The active ingredients in cannabis, termed cannabinoids, affect multiple functions human body, including coordination, motor skills, memory, response time external stimuli, even judgment. Cannabinoids are a unique class terpeno-phenolic compounds, with 120 molecules discovered so far. There certain situations when people under influence may be risk themselves public safety. Over past two decades, there has been growing research interest detecting cannabinoids from various biological matrices. is need develop rapid, accurate, reliable method oral fluid as it can reveal recent intake comparison urine specimens, which only show history consumption. Significant improvements continuously made analytical formats technologies, mainly concerning improving their sensitivity, miniaturization, making them more user-friendly. Additionally, sample collection pretreatment extensively studied, specific devices collecting specimens perfected allow rapid effective collection. This review presents findings regarding use preferred matrix cannabinoid detection point-of-care biosensor diagnostic device. A critical presented, discussing articles, well publicly available data companies that manufacture screening devices. Firstly, conventional methods used detect matrices presented. Secondly, using biosensors discussed, emphasizing specimens. current pressing technological challenges highlights gaps where new solutions implemented.

Language: Английский

Citations

2

Cannabis use and its association with psychopathological symptoms in a Swiss adult population: a cross-sectional analysis DOI Creative Commons

Christoph Felix Mosandl,

Lavinia Baltes-Flückiger,

Jens Kronschnabel

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: May 22, 2024

Background As the most commonly used illicit substance, cannabis is gaining global acceptance through increasing legalization efforts. This shift intensifies need for research to guide policymakers and healthcare providers in harm reduction treatment strategies. Nonetheless, relationship between psychopathological symptoms use remains inadequately understood. Methods A sample of regular consumers completed self-reported assessments depression (Patient Health Questionnaire-9), anxiety (General Anxiety Disorder-7), Attention-Deficit/Hyperactivity Disorder (ADHD; Adult ADHD Self-Report Scale V1.1), psychosis (Early Recognition Inventory based on IRAOS) as well previous black-market patterns. Cannabis Use Identification Test Revised (CUDIT-R) was identify disorder (CUD). To understand symptom load related consumption motives, multiple regression models were performed variables predicting frequency quantity. Linear correlation analyses conducted, adjusting relevant covariates (age, gender, education, alcohol, other substance use). Results Three-hundred-sixty users interested a study regulated access Basel, Switzerland examined. In bivariate analysis, correlated with depressive ( r (358) = 0.16, p 0.003) 0.11, 0.034). quantity 0.15, 0.005), 0.14, 0.008), 0.002). However, adjusted only loads significantly associated 0.006 0.034, respectively) 0.037 0.019, respectively). No significant correlations or remained after adjustment. Conclusion correlate increased cohort users, suggesting potential self-medication nonclinical populations. With rising availability worldwide, these results highlight necessity longitudinal studies disentangle complex dynamics mental health symptoms.

Language: Английский

Citations

2

Herbal Cannabis and Depression: A Review of Findings Published over the Last Three Years DOI Open Access
József Haller

Published: April 25, 2024

Public perception contrasts scientific findings on the depression-related effects of cannabis. However, earlier studies were performed when cannabis was predominantly illegal, its production mostly uncontrolled, and idea medical incipient only. We hypothesized that recent changes in attitudes legislations may have favorably affected research. In addition, publication bias against also decreased. To investigate this hypothesis, we conducted a systematic review research published over last three years. found 156 relevant studies. most cross-sectional studies, depression higher those who consumed than did not. An increase consumption typically followed by an depression, whereas withdrawal from ameliorated cases. Albeit reduced none these placebo controlled. clinical same period, average effect size larger investigated plausibility antidepressant reviewing molecular pharmacological Taken together, reviewed do not support herbal

Language: Английский

Citations

1