Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes

NEJM Evidence, Journal Year: 2024, Volume and Issue: 3(3)

Published: Feb. 27, 2024

BACKGROUND: E-cigarettes are promoted as less harmful than cigarettes. There has not been a direct comparison of health effects e-cigarettes or dual use (concurrently using and cigarettes) with those cigarettes in the general population. METHODS: Studies PubMed, EMBASE, Web Science, PsychINFO published through October 1, 2023, were pooled random-effects meta-analysis if five more studies identified disease outcome. We assessed risk bias Risk Of Bias In Non-randomized Exposure certainty Grading Recommendations, Assessment, Development, Evaluations. Outcomes fewer summarized but pooled. RESULTS: 124 odds ratios (94 cross-sectional 30 longitudinal) from 107 studies. Pooled for current e-cigarette versus cigarette different cardiovascular (odds ratio, 0.81; 95% confidence interval, 0.58 to 1.14), stroke (0.73; 0.47 1.13), metabolic dysfunction (0.99; 0.91 1.09) lower asthma (0.84; 0.74 0.95), chronic obstructive pulmonary (0.53; 0.38 0.74), oral (0.87; 0.76 1.00). increased all outcomes (range, 1.20 1.41). compared nonuse either product (e-cigarette range, 1.24 1.47; use, 1.49 3.29). All included having low bias. Results generally sensitive study characteristics. Limited other suggest that is associated additional diseases. CONCLUSIONS: need reassess assumption provides substantial harm reduction across cigarette-caused diseases, particularly accounting use.

Language: Английский

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IgE-Mediated Allergy and Asymptomatic Sensitization to Cannabis Allergens—Review of Current Knowledge and Presentation of Six Cases

Medicina, Journal Year: 2024, Volume and Issue: 60(6), P. 954 - 954

Published: June 8, 2024

Cannabis allergy is a relatively new phenomenon described in the 1970s. Its increased frequency has been observed over last years due to increasing therapeutic and recreational use of cannabis-based products. Sensitization possibly leading symptoms can occur not only through smoking cannabis, but also ingestion, inhalation pollen, or direct contact. The severity varies from benign pruritus anaphylaxis. There scant information available support clinicians throughout entire process, starting diagnosis ending treatment. In this review, we present six cases patients whom molecular vitro testing revealed sensitization cannabis extract and/or cannabis-derived nsLTP molecules (Can s 3). Based on these cases, raise important questions regarding topic. article discusses current proposals highlights importance further research asymptomatic allergens, which may be ascertained some percentage population.

Language: Английский

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Co-Use of Tobacco Products and Cannabis Is Associated with Absenteeism and Lower Grades in California High School Students

The Journal of Pediatrics, Journal Year: 2024, Volume and Issue: 268, P. 113935 - 113935

Published: Feb. 1, 2024

AbstractObjectiveTo examine the association between co-use of commercial tobacco product (hereafter referred to as tobacco) and cannabis with educational outcomes among high school students.Study designWe analyzed student data from 2021-2022 California Healthy Kids Survey (n=287,653). Current (past-month) or ever use was categorized co-use, only cannabis, neither. Two self-reported were examined: absenteeism grades. Adjusted logistic linear regression models used tobacco/cannabis grades, respectively. Estimates adjusted for individual, peer, covariates, clustering within schools.ResultsCurrent more than double (3.7% vs. 1.7%) similar (3.7%). Almost 18% students reported absenteeism. Compared who neither substance, current had higher odds (adjusted OR 1.41, 95% confidence interval [CI]: 1.33, 1.49) lower grades (β= -0.87, CI: -0.92, -0.82). using alone, also a significant elevated OR=1.19, 1.10, 1.29) -0.39, -0.46, -0.32). Similar results found cannabis.ConclusionsCalifornia youth most likely have Comprehensive efforts prevent reduce substance may improve outcomes. Abstract To students. We schools. cannabis.

Language: Английский

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Immigration status-related exclusive e-cigarette use and cannabis use and their dual use disparities associated with mental health disorder symptoms

Drug and Alcohol Dependence, Journal Year: 2024, Volume and Issue: 255, P. 111083 - 111083

Published: Jan. 6, 2024

E-cigarette and cannabis use has been linked to various health risks, including respiratory cardiovascular conditions. Yet, extant knowledge about the risk factors for exclusive dual of e-cigarettes is limited, especially among immigrants. We examined e-cigarette their associated with mental disorders immigrants U.S.-born.

Language: Английский

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