PubMed,
Journal Year:
2024,
Volume and Issue:
23, P. 212 - 263
Published: Jan. 1, 2024
Niosomes
are
drug
delivery
systems
with
widespread
applications
in
pharmaceutical
research
and
the
cosmetic
industry.
vesicles
of
one
or
more
bilayers
made
non-ionic
surfactants,
cholesterol,
charge
inducers.
Because
their
bilayer
characteristics,
similar
to
liposomes,
niosomes
can
be
loaded
lipophilic
hydrophilic
cargos.
Therefore,
they
stable
cheaper
preparation
than
liposomes.
They
classified
into
four
categories
according
sizes
structures,
namely
small
unilamellar
(SUVs),
large
(LUVs,),
multilamellar
(MLVs),
multivesicular
(MVVs).
There
many
methods
for
niosome
preparation,
such
as
thin-film
hydration,
solvent
injection,
heating
method.
The
current
study
focuses
on
pharmacological
effects
natural
chemical
anti-inflammatory
compounds
kinds
literature
during
past
decade.
We
found
that
most
was
carried
out
load
agents
like
non-steroidal
drugs
(NSAIDs)
vesicles.
studies
revealed
could
improve
agents'
physicochemical
properties,
including
solubility,
cellular
uptake,
stability,
encapsulation,
release
liberation,
efficiency,
oral
bioavailability
topical
absorption.
See
also
graphical
abstract(Fig.
1).
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(20), P. 13862 - 13899
Published: Jan. 1, 2024
The
emergence
and
spread
of
antibiotic-resistant
(AR)
bacterial
strains
biofilm-associated
diseases
have
heightened
concerns
about
exploring
alternative
bactericidal
methods.
WHO
estimates
that
at
least
700
000
deaths
yearly
are
attributable
to
antimicrobial
resistance,
number
could
increase
10
million
annual
by
2050
if
appropriate
measures
not
taken.
Therefore,
the
increasing
threat
AR
bacteria
biofilm-related
infections
has
created
an
urgent
demand
for
scientific
research
identify
novel
therapies.
Nanomaterials
(NMs)
emerged
as
a
promising
due
their
unique
physicochemical
properties,
ongoing
holds
great
promise
developing
effective
NMs-based
treatments
viral
infections.
This
review
aims
provide
in-depth
analysis
NMs
based
mechanisms
combat
infections,
particularly
those
caused
acquired
antibiotic
resistance.
Furthermore,
this
examines
design
features
attributes
can
be
optimized
enhance
efficacy
agents.
In
addition,
plant-based
alternatives
traditional
antibiotics
treating
multidrug-resistant
reduced
toxicity
compared
other
NMs.
potential
plant
mediated
preventing
is
also
discussed.
Overall,
emphasizes
importance
understanding
properties
development
strategies
against
bacteria.
