Synthesis of novel Surfactants from methyl-undecenoate: Properties and Biological activities DOI

Vandana Vemulapalli,

Babi Lakkoju

Journal of the Indian Chemical Society, Journal Year: 2024, Volume and Issue: unknown, P. 101549 - 101549

Published: Dec. 1, 2024

Language: Английский

Fabrication and characterization of algal oil-loaded Pickering emulsion gels stabilized by whey protein isolate/starch complex as an emergency food DOI
Dapeng Yu, Jun Liu, Benzhi Ju

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142782 - 142782

Published: April 1, 2025

Language: Английский

Citations

0

Detecting emerging surfactant pollutants with a highly fluorescent host-guest ensemble DOI

Tejasvi Naik,

Daria V. Berdnikova, Sharmistha Dutta Choudhury

et al.

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 127546 - 127546

Published: April 1, 2025

Language: Английский

Citations

0

Nanobilosome as custom-tailored modality in addressing Alzheimer’s disease: advancements and translational glitches DOI

Biswabhusan Biswal,

Bhabani Sankar Satapathy, Laxmidhar Maharana

et al.

Journal of Dispersion Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 32

Published: April 11, 2025

Language: Английский

Citations

0

State-of-the-art surfactants as biomedical game changers: unlocking their potential in drug delivery, diagnostics, and tissue engineering DOI

Karuppiah Nagaraj,

Subramaniam Kamalesu

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125590 - 125590

Published: April 1, 2025

Language: Английский

Citations

0

Interactions of oral permeation enhancers with lipid membranes in simulated intestinal environments DOI Creative Commons

Nanna Wichmann Larsen,

Serhii Kostrikov, Morten B. Hansen

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 654, P. 123957 - 123957

Published: Feb. 29, 2024

The oral bioavailability of therapeutic peptides is generally low. To increase peptide transport across the gastrointestinal barrier, permeation enhancers are often used. Despite their widespread use, mechanistic knowledge limited. address this, we here investigate interactions six commonly used with lipid membranes in simulated intestinal environments. Specifically, study sodium caprate, dodecyl maltoside, cholate, sulfate, melittin, and penetratin epithelial cell-like model membranes. mimic molecular composition real environment, experiments performed two drugs salmon calcitonin desB30 insulin fasted-state fluid. Besides providing a comparison membrane studied enhancers, our results demonstrate that as well intestinal-fluid components may substantially change activity enhancers. This highlights importance testing enhancement realistic physiological environments carefully choosing enhancer for each individual drug.

Language: Английский

Citations

3

Caffeic Acid Phosphanium Derivatives: Potential Selective Antitumor, Antimicrobial and Antiprotozoal Agents DOI Open Access
Miloš Lukáč,

Lívia Slobodníková,

Martin Mrva

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 1200 - 1200

Published: Jan. 18, 2024

Caffeic acid (CA) is one of the most abundant natural compounds present in plants and has a broad spectrum beneficial pharmacological activities. However, some cases, synthetic derivation original molecules can expand their scope. This study focuses on synthesis caffeic phosphanium derivatives with ambition increasing biological Four salts (CAPs) were synthesized tested for cytotoxic, antibacterial, antifungal, amoebicidal activity vitro, aim identifying best area medicinal use. CAPs exhibited significantly stronger cytotoxic against cell lines (HeLa, HCT116, MDA-MB-231 MCF-7, A2058, PANC-1, Jurkat) comparison to acid. Focusing Jurkat cells (human leukemic T lymphoma), IC50 value ranged from 0.9 8.5 μM while CA was >300 μM. Antimicrobial testing also confirmed higher selected microbes CA, especially Gram-positive bacteria (MIC 13-57 μM) yeast Candida albicans μM). The anti-Acanthamoeba studied two pathogenic Acanthamoeba strains. In case A. lugdunensis, all revealed inhibitory effect (EC50 74-3125 than (>105 µM), quina strain, inhibition observed three 44-291 newly quaternary selective antitumor action appeared be promising antimicrobial agents topical application, as well potential further research.

Language: Английский

Citations

2

Comparative study of greywater treatment using activated carbon and woodchip biochar for surfactant and organic matter removal DOI
Antonio Faggiano, Maria Ricciardi, Oriana Motta

et al.

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: unknown, P. 129861 - 129861

Published: Sept. 1, 2024

Language: Английский

Citations

2

Encapsulation of astaxanthin in OSA-starch based amorphous solid dispersions with HPMCAS-HF/Soluplus® as effective recrystallization inhibitor DOI

Yinglan Li,

Qipeng Wei,

Jianshuo Su

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135421 - 135421

Published: Sept. 1, 2024

Language: Английский

Citations

2

LabrafacTM MC60 is an efficacious intestinal permeation enhancer for macromolecules: Comparisons with Labrasol® ALF in ex vivo and in vivo rat studies DOI Creative Commons
Fiona McCartney, Philippe Caisse, Camille Dumont

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 661, P. 124353 - 124353

Published: June 22, 2024

Labrafac™ MC60 (glycerol monocaprylocaprate) is a lipid-based excipient used in oral formulations as solubiliser. Due to the high proportions of established permeability enhancers, caprylate (C

Language: Английский

Citations

0

Effects of Commonly used Surfactants, Poloxamer 188 and Tween 80, on the Drug Transport Capacity of Intestinal Glucose Transporters DOI
Jiasheng Chen,

Zhenzhen Chen,

Wentao Wang

et al.

AAPS PharmSciTech, Journal Year: 2024, Volume and Issue: 25(6)

Published: July 12, 2024

Language: Английский

Citations

0