
Pharmacological Research, Journal Year: 2024, Volume and Issue: unknown, P. 107533 - 107533
Published: Nov. 1, 2024
Language: Английский
Pharmacological Research, Journal Year: 2024, Volume and Issue: unknown, P. 107533 - 107533
Published: Nov. 1, 2024
Language: Английский
Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126541 - 126541
Published: Nov. 1, 2024
Language: Английский
Citations
4Published: Jan. 1, 2024
Language: Английский
Citations
0Bioscience Reports, Journal Year: 2024, Volume and Issue: 44(9)
Published: Sept. 1, 2024
Abstract Myelination of axons is a key determinant fast action potential propagation, axonal health and circuit function. Previously considered static structure, it now clear that myelin dynamically regulated in response to neuronal activity the central nervous system (CNS). However, how activity-dependent signals are conveyed oligodendrocytes remains unclear. Here, we review mechanisms by which neurons could communicate changing levels myelin, with focus on accumulating body evidence support vesicular signalling directly onto sheaths. We discuss recent vivo findings fusion neurotransmitter vesicles from non-synaptic sites, modulation this regulates stability growth also consider sense respond axon-derived initiate remodelling, relevance these adaptations for propose represents an important underappreciated mode communication can transmit activity-regulated myelinating and, potentially, more broadly other cell types CNS.
Language: Английский
Citations
0Advanced Drug Delivery Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 115473 - 115473
Published: Nov. 1, 2024
Language: Английский
Citations
0Pharmacological Research, Journal Year: 2024, Volume and Issue: unknown, P. 107533 - 107533
Published: Nov. 1, 2024
Language: Английский
Citations
0